Sec-butomidate

Sec-butomidate

Identifiers
IUPAC name but-2-yl 3-[1-phenylethyl]imidazole-4-carboxylate
PubChem CID	172990294
ChemSpider	129767793
Chemical and physical data
Formula	C16H20N2O2
Molar mass	272.348 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(C1=CN=CN1C(C2=CC=CC=C2)C)OC(C)CC
InChI InChI=1S/C16H20N2O2/c1-4-12(2)20-16(19)15-10-17-11-18(15)13(3)14-8-6-5-7-9-14/h5-13H,4H2,1-3H3 Key:ISSGGUZEEXZEAS-UHFFFAOYSA-N

Sec-butomidate is an anesthetic drug related to etomidate, which has been sold as a designer drug as an active ingredient in e-cigarette liquids marketed under names such as space oil or kpods. It has a sec-butyl ester group in place of the ethyl ester of etomidate. ^{[1] [2] [3] [4]}

References

1. Fan Y, Chen X, Wu H, Ke X, Chen H, Xu Y, et al. (November 2025). "Leveraging mass spectrometry fragmentation patterns for accelerated screening and structural elucidation of new etomidate analogues in suspect samples". Journal of Pharmaceutical and Biomedical Analysis. 265 117023. doi:10.1016/j.jpba.2025.117023. PMID   40532400.
2. Bai S, Qian Z, Chen Y, Liu S, Wang F, Liu F (September 2025). "Traceability of etomidate and its analogs in biological samples using "specific" metabolites". Analytical Methods. 17 (36): 7207–7216. doi:10.1039/D5AY00773A. PMID   40879556.
3. Bai S, Li M, Tang S, Wan S, Wu R, Chen L, et al. (2025). "Drug substitutes - Insights on benefits, risks, detection methods, and management strategies: a systematic review". Frontiers in Psychiatry. 16 1600212. doi: 10.3389/fpsyt.2025.1600212 . PMC   12310920 . PMID   40747264.
4. "Substance details: Sec-Butomidate". UNODC. 2025.