3,3-Diethyl-2-pyrrolidinone

3,3-Diethyl-2-pyrrolidinone

Clinical data
ATC code	none
Identifiers
IUPAC name 3,3-Diethylpyrrolidin-2-one
CAS Number	175698-05-2  N
PubChem CID	9793807
ChemSpider	7969574  Y
UNII	YW6BG9J9SK
ChEBI	CHEBI:180486
ChEMBL	ChEMBL293075  Y
CompTox Dashboard (EPA)	DTXSID60430723
ECHA InfoCard	100.162.031
Chemical and physical data
Formula	C8H15NO
Molar mass	141.214 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCC1(CC)CCNC1=O
InChI InChI=1S/C8H15NO/c1-3-8(4-2)5-6-9-7(8)10/h3-6H2,1-2H3,(H,9,10) Y Key:WYPUMACPRYGQOM-UHFFFAOYSA-N Y
NY  (what is this?)    (verify)

3,3-Diethyl-2-pyrrolidinone (DEABL) is an anticonvulsant drug most closely related to pyrithyldione and gabapentin. ^[1] It was found to extend lifespan in the nematode worms Caenorhabditis elegans . ^[2]

References

1. Hill MW, Reddy PA, Covey DF, Rothman SM (July 1998). "Contribution of subsaturating GABA concentrations to IPSCs in cultured hippocampal neurons". The Journal of Neuroscience. 18 (14): 5103–11. doi:10.1523/JNEUROSCI.18-14-05103.1998. PMC   6793480 . PMID   9651194.
2. Evason K, Huang C, Yamben I, Covey DF, Kornfeld K (January 2005). "Anticonvulsant medications extend worm life-span". Science. 307 (5707): 258–62. Bibcode:2005Sci...307..258E. doi:10.1126/science.1105299. PMID   15653505. S2CID   22154410.