Hexethal

Hexethal

Clinical data
Other names	Sodium 5-ethyl-5-hexylbarbiturate, Ortal, Hebaral
ATC code	none
Legal status
Legal status	CA: Schedule IV
Identifiers
IUPAC name sodium 5-ethyl-5-hexyl-4,6-dioxo-1H-pyrimidin-2-olate
CAS Number	144-00-3  Y
PubChem CID	8941
ChemSpider	8597  Y
UNII	ATA79U054W
CompTox Dashboard (EPA)	DTXSID00162591
Chemical and physical data
Formula	C12H19N2NaO3
Molar mass	262.285 g·mol−1
3D model (JSmol)	Interactive image
SMILES [Na+].O=C1/N=C(/[O-])NC(=O)C1(CCCCCC)CC
InChI InChI=1S/C12H20N2O3.Na/c1-3-5-6-7-8-12(4-2)9(15)13-11(17)14-10(12)16;/h3-8H2,1-2H3,(H2,13,14,15,16,17);/q;+1/p-1 Y Key:HXUAXLUDTCGASZ-UHFFFAOYSA-M Y
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Hexethal (Ortal) is a barbiturate derivative invented in the 1940s. It has sedative, anxiolytic, muscle relaxant, and anticonvulsant properties, and was used primarily as an anaesthetic in veterinary medicine. ^[1]

Hexethal is considered similar in effects to pentobarbital, with a very fast onset of action but short duration of effects.

References

1. Butler TC (October 1950). "The rate of penetration of barbituric acid derivatives into the brain". The Journal of Pharmacology and Experimental Therapeutics. 100 (2): 219–26. PMID   14784958.