Obovatol

Last updated
Obovatol
Obovatol.svg
Names
IUPAC name
5-Prop-2-enyl-3-(4-prop-2-enylphenoxy)benzene-1,2-diol
Identifiers
3D model (JSmol)
ChemSpider
PubChem CID
Properties
C18H18O3
Molar mass 282.339 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Obovatol is a biphenolic anti-inflammatory, anxiolytic, and nootropic isolated from the bark of Magnolia obovata . [1] It is a biphenyl lignan. [2]

Related Research Articles

<i>Magnolia</i> Genus of angiosperms

Magnolia is a large genus of about 210 flowering plant species in the subfamily Magnolioideae of the family Magnoliaceae. It is named after French botanist Pierre Magnol.

<i>Chamaecyparis obtusa</i> Species of plant (cypress tree)

Chamaecyparis obtusa is a species of cypress native to central Japan in East Asia, and widely cultivated in the temperate northern hemisphere for its high quality timber and ornamental qualities, with many cultivars commercially available.

<i>Magnolia officinalis</i>

Magnolia officinalis is a species of Magnolia native to the mountains and valleys of China at altitudes of 300–1500 m.

The lignans are a large group of low molecular weight polyphenols found in plants, particularly seeds, whole grains, and vegetables. The name derives from the Latin word for "wood". Lignans are precursors to phytoestrogens. They may play a role as antifeedants in the defense of seeds and plants against herbivores.

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Arame, sea oak is a species of kelp, of the brown algae, best known for its use in Japanese cuisine.

Honokiol

Honokiol is a lignan isolated from the bark, seed cones, and leaves of trees belonging to the genus Magnolia. It has been identified as one of the chemical compounds in some traditional eastern herbal medicines along with magnolol, 4-O-methylhonokiol, and obovatol.

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Magnolol

Magnolol is an organic compound that is classified as lignan. It is a bioactive compound found in the bark of the Houpu magnolia or in M. grandiflora. The compound exists at the level of a few percent in the bark of species of magnolia, the extracts of which have been used in traditional Chinese and Japanese medicine. In addition to magnolol, related lignans occur in the extracts including honokiol, which is an isomer of magnolol.

<i>Magnolia × wieseneri</i>

Magnolia × wieseneri is a hybrid plant in the genus Magnolia and family Magnoliaceae. A small tree or large shrub with white highly fragrant blooms, it is the progeny of Magnolia sieboldii and Magnolia obovata.

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Enterolactone

Enterolactone is a organic compound classified as an enterolignan. It is formed by the action of intestinal bacteria on plant lignan precursors present in the diet.

Macelignan

Macelignan (Anwulignan) is a lignan. It can be found in Myristica fragrans, the nutmeg.

Gintonin Protein found in [[ginseng]]

Gintonin is a glycolipoprotein fraction isolated from ginseng. The non-saponin ingredient was designated as gintonin, where gin was derived from ginseng, ton from the tonic effects of ginseng, and in from protein. The main component of gintonin is a complex of lysophosphatidic acids (LPA) and ginseng proteins such as Ginseng major latex-like protein151 (GLP151) and ginseng ribonuclease-like storage protein.

4-<i>O</i>-Methylhonokiol

4-O-Methylhonokiol is a neolignan, a type of phenolic compound. It is found in the bark of Magnolia grandiflora and in M. virginiana flowers.

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Pluviatilol

Pluviatilol is lignan. It is a Lindera obtusiloba isolate with anti-allergic activity.

Nyasol

Nyasol, also known as cis-hinokiresinol or as (Z)-hinokiresinol, is a lignan that is found in Anemarrhena asphodeloides. It has estrogenic activity, acting as a selective agonist of the ERβ, and hence is a phytoestrogen. In addition, (-)-nyasol has been found to inhibit the production of eicosanoids and nitric oxide in vitro and shows anti-inflammatory effects.

References

  1. ↑ Choi, DY; Lee, JW; Peng, J; Lee, YJ; Han, JY; Lee, YH; Choi, IS; Han, SB; Jung, JK; Lee, WS; Lee, SH; Kwon, BM; Oh, KW; Hong, JT (2012). "Obovatol improves cognitive functions in animal models for Alzheimer's disease". Journal of Neurochemistry. 120 (6): 1048–59. doi: 10.1111/j.1471-4159.2011.07642.x . PMID   22212065. S2CID   25896721.
  2. ↑ Obovatol and obovatal, novel biphenyl ether lignans from the leaves of Magnolia obovata Thunb. K Ito, T Iida, K Ichino, M Tsunezuka and M Hattori, … and Pharmaceutical Bulletin, 1982
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