Triflubazam

Triflubazam

Identifiers
IUPAC name 1-methyl-5-phenyl-7-(trifluoromethyl)-1H-1,5-benzodiazepine-2,4(3H,5H)-dione
CAS Number	22365-40-8  Y
PubChem CID	31157
ChemSpider	28907  Y
UNII	80D8H0388T
KEGG	D06231
ChEMBL	ChEMBL2107285
CompTox Dashboard (EPA)	DTXSID40176899
Chemical and physical data
Formula	C17H13F3N2O2
Molar mass	334.298 g·mol−1
3D model (JSmol)	Interactive image
SMILES FC(F)(C1=CC(N(C2=CC=CC=C2)C(CC(N3C)=O)=O)=C3C=C1)F
InChI InChI=1S/C17H13F3N2O2/c1-21-13-8-7-11(17(18,19)20)9-14(13)22(16(24)10-15(21)23)12-5-3-2-4-6-12/h2-9H,10H2,1H3 Y Key:DMNPCIKBNDKNTO-UHFFFAOYSA-N Y
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Triflubazam ^[1] is a drug which is a 1,5-benzodiazepine derivative, related to clobazam. ^[2] It has sedative and anxiolytic effects, with a long half-life and duration of action. ^{[3] [4] [5]}

See also

• Benzodiazepine
• Clobazam
• CP-1414S
• Triflunordazepam

References

1. US 3660381,Karl-Heinz Weber KH, Merz H, K Zeile, Giesemann R, Danneberg P,"5-Aryl-1H-1,5-benzodiazepine-2,4-diones",issued 2 May 1972, assigned to CH Boehringer Sohn AG and Co KG 
2. Lundbeck Institute (2003). "triflubazam". psychotropics.dk. Retrieved 17 November 2010.
3. Itil TM, Akpinar S, Fink M, Polvan N, Huque M, Sungurbey K (March 1976). "Controlled clinical and quantitative EEG studies of triflubazam (ORF 8063) in patients with anxiety syndrome". Current Therapeutic Research, Clinical and Experimental. 19 (3): 307–15. PMID   5248.
4. Csanalosi I, Pereira-Oran J, Case G, et al. (1977). "Triflubazam (ORF 8063), a new benzodiazepine in anxiety neurosis". Current Therapeutic Research. 22: 166–171.
5. Nicholson AN, Stone BM, Clarke CH (October 1977). "Effect of the 1,5-benzodiazepines, clobazam and triflubazam, on sleep in man". British Journal of Clinical Pharmacology. 4 (5): 567–72. doi:10.1111/j.1365-2125.1977.tb00787.x. PMC   1429140 . PMID   20917.