Deschloroetizolam

Deschloroetizolam

Clinical data
Dependence liability	Moderate
Routes of administration	Oral, sublingual, rectal
Legal status
Legal status	DE: NpSG (Industrial and scientific use only) UK: Class C Illegal in Sweden
Identifiers
IUPAC name 4-phenyl-2-ethyl-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
CAS Number	40054-73-7  Y
PubChem CID	827322
ChemSpider	722596
UNII	69HF7J354D
CompTox Dashboard (EPA)	DTXSID901032639
Chemical and physical data
Formula	C17H16N4S
Molar mass	308.40 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCC1=CC2=C(S1)N3C(=NN=C3CN=C2C4=CC=CC=C4)C
InChI InChI=1S/C17H16N4S/c1-3-13-9-14-16(12-7-5-4-6-8-12)18-10-15-20-19-11(2)21(15)17(14)22-13/h4-9H,3,10H2,1-2H3 Key:JIOBORXCOGMHSV-UHFFFAOYSA-N

Deschloroetizolam (also known as Etizolam-2) is a thienotriazolodiazepine that is the dechlorinated analog of the closely related etizolam. ^{[1] [2] [3]} The compound has been sold as a designer drug. ^{[4] [5] [6]}

Legal status

Deschloroetizolam is classified and controlled as a hazardous substance in Sweden as of on October 15, 2015. ^[7]

Deschloroetizolam was made schedule I at the state level in Alabama on July 15, 2024. ^[8]

See also

• Adinazolam
• Clonazolam
• Deschloroclotizolam
• Diclazepam
• Etizolam
• Flubromazepam
• Flubromazolam
• Fluetizolam
• Meclonazepam
• Metizolam
• Nifoxipam
• Pyrazolam

References

1. Weber KH, Bauer A, Langbein A, Daniel H (September 1978). "Heteroaromaten mit anellierten Siebenringen, III. Umwandlung von Thienotriazolooxazepinen in Diazepine". Justus Liebigs Annalen der Chemie (in German). 1978 (8): 1257–1265. doi:10.1002/jlac.197819780806.
2. US 3904641,Nakanishi M, Tahara T, Araki K, Shiroki M,"Triazolothienodiazepine compounds",published 1975-09-09, assigned to Yoshitomi Pharmaceutical Industries, Ltd. 
3. EP 0776892,Hiroshi K, Syuji E, Hideaki S, Minoru M, Kenichi O,"Thienylazole compound and thienotriazolodiazepine compound",published 4 June 1997, assigned to Yoshitomi Pharmaceutical Industries, Ltd. 
4. Pettersson Bergstrand M, Helander A, Hansson T, Beck O (April 2017). "Detectability of designer benzodiazepines in CEDIA, EMIT II Plus, HEIA, and KIMS II immunochemical screening assays". Drug Testing and Analysis. 9 (4): 640–645. doi:10.1002/dta.2003. PMID   27366870.
5. Manchester KR, Maskell PD, Waters L (March 2018). "Experimental versus theoretical log D_7.4 , pK_a and plasma protein binding values for benzodiazepines appearing as new psychoactive substances". Drug Testing and Analysis. 10 (8): 1258–1269. doi:10.1002/dta.2387. PMID   29582576. S2CID   31098917.
6. Manchester KR, Waters L, Haider S, Maskell PD (July 2022). "The blood-to-plasma ratio and predicted GABA_A-binding affinity of designer benzodiazepines". Forensic Toxicology. 40 (2): 349–356. doi:10.1007/s11419-022-00616-y. PMC   9715504 . PMID   36454409. S2CID   247455284.
7. "Nya substanser klassas som narkotika eller hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. 18 August 2015.
8. https://www.alabamapublichealth.gov/blog/assets/controlledsubstanceslist.pdf ^{[ bare URL PDF ]}