 | |
| Names | |
|---|---|
| Preferred IUPAC name 1-[2-(Diphenylmethoxy)ethyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine | |
| Identifiers | |
| |
3D model (JSmol) | |
| ChEBI | |
| ChEMBL | |
| ChemSpider | |
PubChem CID | |
| UNII | |
CompTox Dashboard (EPA) | |
| |
| |
| Properties | |
| C28H32N2 | |
| Molar mass | 396.578 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
GBR-12783 is a psychostimulant which acts as a selective dopamine reuptake inhibitor. [1]
The Coral Sea is a marginal sea of the South Pacific off the northeast coast of Australia, and classified as an interim Australian bioregion. The Coral Sea extends 2,000 kilometres (1,200 mi) down the Australian northeast coast. The sea was the location for the Battle of the Coral Sea, a major confrontation during World War II between the navies of the Empire of Japan, and the United States and Australia.
Middleweight is a weight class in combat sports.
A dopamine reuptake inhibitor (DRI) is a class of drug which acts as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action of the dopamine transporter (DAT). Reuptake inhibition is achieved when extracellular dopamine not absorbed by the postsynaptic neuron is blocked from re-entering the presynaptic neuron. This results in increased extracellular concentrations of dopamine and increase in dopaminergic neurotransmission.
The 1995 European Athletics Junior Championships was held in Nyíregyháza, Hungary on July 27–30.
The 1977 Summer Universiade, also known as the IX Summer Universiade or World University Games, took place in Sofia, Bulgaria.
Walter J. Koladza Airport,, also known as the Great Barrington Airport, is a privately owned airport in Great Barrington, Massachusetts open to the public. It has a single 2,579 ft runway. The airport is named after Walter J. Koladza, who was a test pilot during World War II, and the owner of the airport for nearly 60 years.
Vanoxerine is a piperazine derivative which is a potent and selective dopamine reuptake inhibitor (DRI). Vanoxerine binds to the target site on the dopamine transporter (DAT) ~ 50 times more strongly than cocaine, but simultaneously inhibits the release of dopamine. This combined effect only slightly elevates dopamine levels, giving vanoxerine only mild stimulant effects. Vanoxerine has also been observed to be a potent blocker of the IKr (hERG) channel. Vanoxerine also binds with nanomolar affinity to the serotonin transporter.
Molesey Boat Club is a rowing club between Molesey Lock and Sunbury Lock on the River Thames in England. The club was founded in 1866 where its boathouse stands with hardstanding next to the Thames Path.
At the 1948 Winter Olympics in St. Moritz, a winter pentathlon competition was held. It was one of two demonstration sports held at these Games.
The FEI European Show Jumping Championships is the European Championship for the equestrian discipline of show jumping. First held in 1957 in Rotterdam, and on an annual basis, it is held every two years, on the years between Olympic Games and World Equestrian Games.
GBR-12935 is a piperazine derivative which is a potent and selective dopamine reuptake inhibitor. It was originally developed in its 3H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labelling of dopamine transporter proteins. This has led to potential clinical uses in the diagnosis of Parkinson's disease, although selective radioligands such as Ioflupane (¹²³I) are now available for this application. GBR-12935 is now widely used in animal research into Parkinson's disease and the dopamine pathways in the brain.
DBL-583 is a selective dopamine reuptake inhibitor of the piperazine chemical class. It is the decanoate ester of a hydroxy vanoxerine. DBL-583 breaks down very slowly in the body, lasting for up to a month after a single injection.
Football 7-a-side at the 2012 Summer Paralympics was held in London at the Olympic Hockey Centre, from 1 September to 9 September. Football 7-a-side is played by athletes with cerebral palsy, a condition characterized by impairment of muscular coordination. 96 footballers are expected to compete for one set of medals.
Ukraine competed at the 2012 Summer Paralympics in London, United Kingdom, from 29 August to 9 September 2012.
GBR-13069 is a psychostimulant and selective dopamine reuptake inhibitor.
GBR-13098 is a psychostimulant and selective dopamine uptake inhibitor.
GBR-13119 is a psychostimulant and dopamine re-uptake inhibitor.
Delanterone (INN), also known as 1α-methylandrosta-4,16-dien-3-one, is a steroidal antiandrogen described as an anti-acne agent which was never marketed. The compound showed poor efficacy as an antiandrogen in vivo in animals, suggestive of low activity or a short terminal half-life, and likely in relation to this was not further developed. It was described and characterized in the literature in 1977.
The Cadet World Championship are international sailing regattas in the Cadet class organized by the International Sailing Federation and the International Cadet Class Association.
Great British Railways (GBR) is a planned state-owned public body that will oversee rail transport in Great Britain from 2023, with the exception of Transport for London, Merseytravel services, and light rail and trams elsewhere in England. It will replace Network Rail as the operator of rail infrastructure across all of Great Britain. It will also control the contracting of passenger train services, the setting of fares and timetables, and the collection of fare revenue, with the exception of non-crossborder services in Scotland and Wales.
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