2C-B-PP

2C-B-PP

Clinical data
ATC code	none
Identifiers
IUPAC name 1-(2,5-dimethoxy-4-bromophenyl)piperazine
CAS Number	100939-87-5  Y
PubChem CID	4738744
UNII	9AF4JQU2FM
ChEMBL	ChEMBL348140
Chemical and physical data
Formula	C12H17BrN2O2
Molar mass	301.184 g·mol−1
3D model (JSmol)	Interactive image
SMILES COC1=CC(=C(C=C1N2CCNCC2)OC)Br
InChI InChI=1S/C12H17BrN2O2/c1-16-11-8-10(12(17-2)7-9(11)13)15-5-3-14-4-6-15/h7-8,14H,3-6H2,1-2H3 Key:JLAQUWGWRNMYGA-UHFFFAOYSA-N

2,5-dimethoxy-4-bromophenylpiperazine (2C-B-PP) is a drug of the phenylpiperazine class. It acts as an agonist at serotonin receptors, and in studies on rats substituted for the psychedelic amphetamine derivative DOM with around 1/10 the potency but similar rates of stimulus-appropriate responding at the highest dose. ^{[1] [2] : 867–868}

See also

• 2C-B-aminorex
• 2C-B-BZP
• 3-Chloro-4-fluorophenylpiperazine
• CPD-1
• ORG-12962
• Quipazine
• Substituted piperazine

References

1. Lyon RA, Titeler M, McKenney JD, Magee PS, Glennon RA (May 1986). "Synthesis and evaluation of phenyl- and benzoylpiperazines as potential serotonergic agents". Journal of Medicinal Chemistry. 29 (5): 630–634. doi:10.1021/jm00155a008. PMID   3701781.
2. Trachsel D, Lehmann D, Enzensperger C (2013). Phenethylamine: Von der Struktur zur Funktion. Nachtschatten Verlag AG. ISBN   978-3-03788-700-4.