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| Other names | 4-Cyclopropylmethylthio-2,5-dimethoxyphenethylamine; 2,5-Dimethoxy-4-cyclopropylmethylthiophenethylamine |
| Routes of administration | Oral [1] |
| Drug class | Serotonergic psychedelic; Hallucinogen |
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| Duration of action | 10–15 hours [1] |
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| Formula | C14H21NO2S |
| Molar mass | 267.39 g·mol−1 |
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2C-T-8, also known as 4-cyclopropylmethylthio-2,5-dimethoxyphenethylamine, is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin, sometimes used as an entheogen.
In his book PiHKAL , Shulgin lists the dosage range as 30 to 50 mg. [1] 2C-T-8 is generally taken orally and effects typically last 10 to 15 hours. Experiences have varied between insight and creativity at low doses to hypersensitivity and paranoia at higher doses. A "thinking-connection" that is characteristic of the 2C-T group is evident in this chemical in stark contrast to the "pure euphoria" of phenethylamines such as MDMA. [1]
The toxicity of 2C-T-8 is not well documented. 2C-T-8 is somewhat less potent than 2C-T-7, but it may be expected that at higher doses it would display similar toxicity to that of other phenethylamines of the 2C-T family.
There have been no confirmed deaths due to 2C-T-8,[ citation needed ] though this may in part be due to its rarity and limited usage. Of the 2C-T family, there have been a few confirmed deaths due to 2C-T-7, which involved either insufflating large (>30 mg) doses [2] [3] and in one case an unknown oral dose was combined with 200 mg MDMA. [4]
The full name of the chemical is 2,5-dimethoxy-4-cyclopropyl methyl thio phenethylamine. The compound is reported to have a bad taste and smell.[ citation needed ]
2C-T-8 is unscheduled and uncontrolled in the United States, but possession and sales of 2C-T-8 will probably be prosecuted under the Federal Analog Act because of its structural similarities to 2C-T-7. However, 2C-T-8, unlike many other phenethylamines has not been sold by internet retailers. In the wake of Operation Web Tryp in July 2004, the issue of possession and sales of 2C-T-8 and other similar chemicals will probably be resolved in the courtroom as will the fate of this rare but unique psychedelic.[ needs update ]
As of October 31, 2016, 2C-T-8 is a controlled substance (Schedule III) in Canada. [5]