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| Other names | 4-Bromo-2,5-dimethoxy-N-hydroxyphenethylamine; 2,5-Dimethoxy-4-bromo-N-hydroxyphenethylamine; N-Hydroxy-4-bromo-2,5-dimethoxyphenethylamine; N-Hydroxy-2C-B |
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| Formula | C10H14BrNO3 |
| Molar mass | 276.130 g·mol−1 |
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2C-B-OH, also known as 4-bromo-2,5-dimethoxy-N-hydroxyphenethylamine or as N-hydroxy-2C-B, is a chemical compound of the phenethylamine and 2C families related to the psychedelic drug 2C-B. [1] It is the N-hydroxy derivative of 2C-B and is structurally related to the HOT-x psychedelics like HOT-2 (N-hydroxy-2C-T-2), HOT-7 (N-hydroxy-2C-T-7), and HOT-17 (N-hydroxy-2C-T-17). [2] Unlike the HOT-x drugs however, 2C-B-OH was not included or mentioned by Alexander Shulgin in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved). [2] The HOT-x psychedelics, as well as the MDxx entactogens MDOH (N-hydroxy-MDA) and FLEA (MDMOH; N-hydroxy-MDMA), may act as prodrugs of their N-unsubstituted analogues, for instance HOT-2 into 2C-T-2. [2] The chemical synthesis of 2C-B-OH has been described. [1] The drug was first described in the scientific literature by Leth-Petersen and colleagues in 2016. [1]
