2C-T-30

Last updated

2C-T-30
2C-T-30.svg
Clinical data
Other names2C-T-FB; 2C-T-FBu; 4-(4-Fluorobutylthio)-2,5-dimethoxyphenethylamine
Routes of
administration 		Oral [1]
Drug class Serotonin receptor modulator; Serotonin 5-HT2A receptor agonist
ATC code
  • None
Identifiers
  • 2-[4-(4-fluorobutylsulfanyl)-2,5-dimethoxyphenyl]ethanamine
PubChem CID
Chemical and physical data
Formula C14H22FNO2S
Molar mass 287.39 g·mol−1
3D model (JSmol)
  • COC1=CC(=C(C=C1CCN)OC)SCCCCF
  • InChI=1S/C14H22FNO2S/c1-17-12-10-14(19-8-4-3-6-15)13(18-2)9-11(12)5-7-16/h9-10H,3-8,16H2,1-2H3
  • Key:BILSBDMCLLFSAV-UHFFFAOYSA-N

2C-T-30, also known as 2C-T-FB or as 4-(4-fluorobutylthio)-2,5-dimethoxyphenethylamine, is a serotonin receptor modulator of the phenethylamine and 2C families. [1] [2] [3] It is the derivative of 2C-T in which the 4-methylthio group has been replaced with a 4-(4-fluorobutylthio) group. [1] [2] According to Daniel Trachsel, 2C-T-30 was not clearly active at a dose of 6 mg plus 3 mg orally and its duration and effects are unknown. [2] [4] However, it was said that it might have helped increase ability to concentrate on tasks. [2] The drug is a potent partial agonist of the serotonin 5-HT2A receptor and also interacts with other serotonin receptors and targets. [3] [1] The chemical synthesis of 2C-T-30 has been described. [5] 2C-T-30 was first described in the scientific literature by Trachsel in 2003. [5] It is a controlled substance in Canada under phenethylamine blanket-ban language. [6]

Contents

See also

References

  1. 1 2 3 4 Trachsel D, Lehmann D, Enzensperger C (2013). Phenethylamine: von der Struktur zur Funktion [Phenethylamines: From Structure to Function]. Nachtschatten-Science (in German) (1 ed.). Solothurn: Nachtschatten-Verlag. ISBN   978-3-03788-700-4. OCLC   858805226. Archived from the original on 21 August 2025.
  2. 1 2 3 4 Trachsel D (2012). "Fluorine in psychedelic phenethylamines". Drug Testing and Analysis. 4 (7–8): 577–590. doi:10.1002/dta.413. PMID   22374819. Further homologs, 2C-T-19 (41; Ki = 14nM) and 2C-T-30 (42; Ki = 47nM) were tested in radioligand binding assays using [3 H] LSD labelled cloned h5-HT2A receptors, indicating a high affinity of 41 at this binding site. In this case fluorine seemed to decrease affinity slightly by a factor of around three. Virtually nothing is known about their human activities. 2C-T-30 (42) was tested up to 6 + 3 mg which revealed no detectable effects.
  3. 1 2 Luethi D, Trachsel D, Hoener MC, Liechti ME (May 2018). "Monoamine receptor interaction profiles of 4-thio-substituted phenethylamines (2C-T drugs)". Neuropharmacology. 134 (Pt A): 141–148. doi:10.1016/j.neuropharm.2017.07.012. PMID   28720478.
  4. ↑ Luethi D, Liechti ME (October 2018). "Monoamine Transporter and Receptor Interaction Profiles in Vitro Predict Reported Human Doses of Novel Psychoactive Stimulants and Psychedelics". The International Journal of Neuropsychopharmacology. 21 (10): 926–931. doi:10.1093/ijnp/pyy047. PMC   6165951 . PMID   29850881.
  5. 1 2 Trachsel D (2003). "Synthese von neuen (Phenylalkyl)aminen zur Untersuchung von Struktur–Aktivitätsbeziehungen. Mitteilung 2: 4-Thio-substituierte [2-(2,5-Dimethoxyphenyl)ethyl]amine (=2,5-Dimethoxybenzolethanamine)" . Helvetica Chimica Acta. 86 (7): 2610–2619. doi:10.1002/hlca.200390210. ISSN   0018-019X . Retrieved 17 November 2025.
  6. ↑ "Controlled Drugs and Substances Act". Department of Justice Canada. Retrieved 19 January 2026.
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