5-Ethyl-DMT

5-Ethyl-DMT

Identifiers
IUPAC name 2-(5-Ethyl-1H-indol-3-yl)-N,N-dimethylethanamine
CAS Number	171783-25-8  Y
PubChem CID	10775128
ChemSpider	8950441  Y
ChEMBL	ChEMBL50492  Y
CompTox Dashboard (EPA)	DTXSID30444736
Chemical and physical data
Formula	C14H20N2
Molar mass	216.328 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN(C)CCc1c[nH]c(ccc2CC)c1c2
InChI InChI=1S/C14H20N2/c1-4-11-5-6-14-13(9-11)12(10-15-14)7-8-16(2)3/h5-6,9-10,15H,4,7-8H2,1-3H3 Y Key:ZEHXYLDGQMEYAX-UHFFFAOYSA-N Y
NY  (what is this?)    (verify)

5-Ethyl-N,N-dimethyltryptamine is a tryptamine derivative which acts as an agonist at the 5-HT_1A and 5-HT_1D serotonin receptors, with around 3x selectivity for 5-HT_1D. ^[1]

See also

• 5-Benzyloxytryptamine
• 5-Carboxamidotryptamine
• 5-Ethoxy-DMT
• 5-Methyl-DMT
• Sumatriptan

References

1. Glennon RA, Hong SS, Bondarev M, Law H, Dukat M, Rakhi S, Power P, Fan E, Kinneau D, Kamboj R, Teitler M, Herrick-Davis K, Smith C (January 1996). "Binding of O-alkyl derivatives of serotonin at human 5-HT1D beta receptors". Journal of Medicinal Chemistry. 39 (1): 314–22. doi:10.1021/jm950498t. PMID   8568822.