6,7-Dihydroxytryptamine

6,7-Dihydroxytryptamine

Clinical data
Other names	6,7-DHT
Drug class	Serotonergic neurotoxin
Identifiers
IUPAC name 3-(2-aminoethyl)-1H-indole-6,7-diol
CAS Number	50584-06-0
PubChem CID	39719
ChemSpider	36316
CompTox Dashboard (EPA)	DTXSID40964793
Chemical and physical data
Formula	C10H12N2O2
Molar mass	192.218 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1=CC(=C(C2=C1C(=CN2)CCN)O)O
InChI InChI=1S/C10H12N2O2/c11-4-3-6-5-12-9-7(6)1-2-8(13)10(9)14/h1-2,5,12-14H,3-4,11H2 Key:JPQILYNPNMIPHV-UHFFFAOYSA-N

6,7-Dihydroxytryptamine (6,7-DHT) is a serotonergic neurotoxin of the tryptamine family. ^{[1] [2]} It is structurally related to the monoamine neurotransmitter serotonin (5-hydroxytryptamine; 5-HT). ^{[1] [2]}

See also

• 4,5-Dihydroxytryptamine (4,5-DHT)
• 5,6-Dihydroxytryptamine (5,6-DHT)
• 5,7-Dihydroxytryptamine (5,7-DHT)
• 4-Hydroxy-5-methoxytryptamine (4-HO-5-MeO-T)

References

1. Nobin A, Björklund A (June 1978). "Degenerative effects of various neurotoxic indoleamines on central monoamine neurons". Annals of the New York Academy of Sciences. 305 (1): 305–327. Bibcode:1978NYASA.305..305N. doi:10.1111/j.1749-6632.1978.tb31531.x. PMID   360938.
2. Massotti M, Scotti de Carolis A, Longo VG (1974). "Effects of three dihydroxylated derivatives of tryptamine on the behavior and on brain amine content in mice". Pharmacology, Biochemistry, and Behavior. 2 (6): 769–776. doi:10.1016/0091-3057(74)90109-9. PMID   4549398.