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Clinical data | |
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Drug class | Serotonergic and dopaminergic neurotoxin |
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Chemical and physical data | |
Formula | C21H21ClFNO |
Molar mass | 357.85 g·mol−1 |
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HPTP is a monoaminergic neurotoxin related to MPTP. [1] [2] [3] [4] It is the dehydration product of haloperidol. [1] [2] [4] The agent is specifically a dopaminergic and serotonergic neurotoxin. [1] HPTP is a prodrug of HPP+, which mediates its monoaminergic neurotoxicity. [1] [2] [4] This is analogous to how MPP+ mediates the neurotoxicity of MPTP. [1] [2] [4] Other related compounds include RHPTP and RHPP+. [5]
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: CS1 maint: DOI inactive as of November 2024 (link)