Allylescaline

Last updated
Allylescaline
Allylescaline.svg
Allylescaline-3d-sticks.png
Clinical data
Other namesAL; Allylmescaline; 4-Allyloxy-3,5-dimethoxyphenethylamine; 3,5-Dimethoxy-4-allyloxyphenethylamine
Routes of
administration 		Oral [1]
Drug class Serotonin receptor modulator; Serotonergic psychedelic; Hallucinogen
ATC code
  • None
Pharmacokinetic data
Duration of action 8–12 hours [1]
Identifiers
  • {3,5-dimethoxy-4-[(prop-2-en-1-yl)oxy]phenyl}ethan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
Formula C13H19NO3
Molar mass 237.299 g·mol−1
3D model (JSmol)
  • COc1cc(cc(OC)c1OCC=C)CCN
  • InChI=1S/C13H19NO3/c1-4-7-17-13-11(15-2)8-10(5-6-14)9-12(13)16-3/h4,8-9H,1,5-7,14H2,2-3H3 X mark.svgN
  • Key:JNUAYHHGCXYBHX-UHFFFAOYSA-N X mark.svgN
   (verify)

Allylescaline (AL), or allylmescaline, also known as 4-allyloxy-3,5-dimethoxyphenethylamine, is a lesser-known psychedelic drug of the phenethylamine and scaline families. [1] It is closely related in structure to mescaline. [1]

Contents

Use and effects

According to Alexander Shulgin in his book PiHKAL (Phenethylamines I Have Known and Loved), the dose range of allylescaline is 20 to 35 mg and its duration is 8 to 12 hours. [1] Allylescaline produces an entactogenic warmth, an entheogenic effect, and a feeling of flowing energy. [1]

Interactions

Pharmacology

The receptor interactions of allylescaline have been studied. [2]

History

Allylescaline was first synthesized by Otakar Leminger in 1972. [3] The compound was later synthesized by Alexander Shulgin and further described in his 1991 book PiHKAL . [1]

Society and culture

Sweden

Allylescaline is illegal in Sweden as of January 2016. [4]

United States

Allylescaline is not directly scheduled under the Controlled Substances Act. However, due to its structural similarities with mescaline, it could potentially be prosecuted under the Federal Analogue Act if sold for human consumption.

See also

References

  1. 1 2 3 4 5 6 7 AL Entry in PiHKAL
  2. ↑ Jain MK, Gumpper RH, Slocum ST, Schmitz GP, Madsen JS, Tummino TA, Suomivuori CM, Huang XP, Shub L, DiBerto JF, Kim K, DeLeon C, Krumm BE, Fay JF, Keiser M, Hauser AS, Dror RO, Shoichet B, Gloriam DE, Nichols DE, Roth BL (July 2025). "The polypharmacology of psychedelics reveals multiple targets for potential therapeutics" (PDF). Neuron. doi:10.1016/j.neuron.2025.06.012. PMID   40683247.
  3. ↑ Leminger, Otakar (1972). "The Chemistry of Alkoxylated Phenethylamines – Part 2". Chemický Průmysl. 22: 553.
  4. ↑ "31 nya ämnen kan klassas som narkotika eller hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. November 2015.


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