PARGY-LAD

Last updated
PARGY-LAD
PARGY-LAD.svg
Clinical data
Other namesPARGYLAD; PROPARGYL-LAD; PROPARGYLLAD; 6-Propynyl-6-nor-LSD; N,N-Diethyl-6-propargyl-6-norlysergamide; N,N-Diethyl-6-(prop-2-yn-1-yl)-9,10-didehydroergoline-8β-carboxamide
Routes of
administration 		Oral [1]
Drug class Serotonin receptor modulator; Serotonergic psychedelic; Hallucinogen
Legal status
Legal status
Identifiers
  • (6aR,9R)-N,N-diethyl-7-prop-2-ynyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
Formula C22H25N3O
Molar mass 347.462 g·mol−1
3D model (JSmol)
  • CCN(CC)C(=O)[C@@H]2C=C1c3cccc4[nH]cc(C[C@H]1N(C2)CC#C)c34
  • InChI=1S/C22H25N3O/c1-4-10-25-14-16(22(26)24(5-2)6-3)11-18-17-8-7-9-19-21(17)15(13-23-19)12-20(18)25/h1,7-9,11,13,16,20,23H,5-6,10,12,14H2,2-3H3/t16-,20-/m1/s1 Yes check.svgY
  • Key:BPJKJUFQSNRQCR-OXQOHEQNSA-N Yes check.svgY
   (verify)

PARGY-LAD, also known as 6-propynyl-6-nor-LSD or 6-propargyl-6-nor-LSD, is a psychedelic drug of the lysergamide family related to lysergic acid diethylamide (LSD). [3]

Contents

Use and effects

PARGY-LAD is hallucinogenic similarly to LSD, but is considerably less potent than LSD, with a dose of 160 μg producing only mild effects, and 500 μg required for full activity. [1]

Interactions

History

PARGY-LAD was developed by David E. Nichols and colleagues at Purdue University in the 1980s [3] and is described by Alexander Shulgin in his 1997 book TiHKAL (Tryptamines I Have Known and Loved). [1]

See also

References

  1. 1 2 3 "#51. PRO-LAD". Shulgin A, Shulgin A (September 1997). TiHKAL: The Continuation. Berkeley, California: Transform Press. ISBN   0-9630096-9-9. OCLC   38503252.
  2. ↑ "Arrêté du 20 mai 2021 modifiant l'arrêté du 22 février 1990 fixant la liste des substances classées comme stupéfiants". www.legifrance.gouv.fr (in French). 20 May 2021.
  3. 1 2 Nichols DE, Oberlender R, McKenna DJ (1991). "Stereochemical Aspects of Hallucinogenesis". In Watson RR (ed.). Biochemistry and Physiology of Substance Abuse. Vol. 3. Boca Raton, Fla.: CRC Press. pp. 1–39. ISBN   978-0-8493-4463-3. OCLC   26748320. TABLE 1 Effects of N-(6)-Alkyl Subtituents on LSD-Like Behavior and Serotonin Receptor Affinity in Rats [...]
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