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Formula C12H16F3NS
Molar mass 263.32 g·mol−1
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Chirality Racemic mixture
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Tiflorex, formerly known as flutiorex, is a stimulant amphetamine. Its most pronounced effect is in suppression of appetite; it has little effect on pulse rate, sleep, or mood. [1] It was found to be twice as potent an anorectic as fenfluramine. [2]

SL 72.340-d was cited to be 4x the anorectant potency of fenfluramine (ED50=1.4 mg/kg vs 5.6 mg/kg). [3]

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  1. Silverstone T, Fincham J, Plumley J (April 1979). "An evaluation of the anorectic activity in man of a sustained release formulation of tiflorex". British Journal of Clinical Pharmacology. 7 (4): 353–6. doi:10.1111/j.1365-2125.1979.tb00945.x. PMC   1429648 . PMID   444355.
  2. Giudicelli JF, Richer C, Berdeaux A (February 1976). "Preliminary assessment of flutiorex, a new anorectic drug, in man". British Journal of Clinical Pharmacology. 3 (1): 113–21. doi:10.1111/j.1365-2125.1976.tb00578.x. PMC   1428817 . PMID   788737.
  3. Stuart S (2013-09-11). Abstracts: Sixth International Congress of Pharmacology. ISBN   9781483152530.