6-EAPB

6-EAPB
Legal status
Legal status	AU:Analogue of MDMA ; CA: Schedule I ; DE: NpSG (Industrial and scientific use only); UK: Class B ; US: Analogue to a Schedule I/II drug(MDMA);
Identifiers
	IUPAC name 1-(benzofuran-6-yl)-N-ethylpropan-2-amine;
CAS Number	1632539-47-9 ;
ChemSpider	57427400 ;
UNII	LWB2M746C9 ;
Chemical and physical data
Formula	C13H17NO
Molar mass	203.285 g·mol−1
3D model (JSmol)	Interactive image ;
	SMILES CCNC(CC1=CC2=C(C=CO2)C=C1)C;
	InChI InChI=1S/C13H17NO.ClH/c1-3-14-10(2)8-11-4-5-12-6-7-15-13(12)9-11;/h4-7,9-10,14H,3,8H2,1-2H3;1H; Key:MUFUSNCKTVRMLR-UHFFFAOYSA-N;

Last updated November 24, 2025

6-EAPB, also known as 1-(benzofuran-6-yl)-N-ethylpropan-2-amine, is a potentially psychedelic and potentially entactogenic drug of the benzofuran class;^[1] it is structurally related to 6-APB and MDMA.

Pharmacology

Pharmacodynamics

6-EAPB is a potent monoamine reuptake inhibitor.^[2] It shows very low potency as a serotonin 5-HT_2A receptor agonist.^[2]

Society and culture

Legal status

As an N-ethyl derivative of 6-APB, 6-EAPB fell outside the scope of the Temporary Class Drug ban issued by the Home Office on June 10, 2013.^[3] The ACMD has advised that 6-EAPB (and other benzofurans) are moved to Class B,^[4] this came into action on 10 June 2014.^[5]

References

↑ Taschwer M, Hofer MG, Schmid MG (October 2014). "Enantioseparation of benzofurys and other novel psychoactive compounds by CE and sulfobutylether β-cyclodextrin as chiral selector added to the BGE". Electrophoresis. 35 (19): 2793–2799. doi:10.1002/elps.201400164. PMID 24930967. S2CID 2937770.
1 2 Stalberga, D., Kronstrand, R., Schranz, B., van Zijl, N., Karlman, S., Aref, S., ... & Gréen, H. (2025). Comprehensive in vitro profiling of traditional and emerging stimulants at monoamine transporters and the 5HT2A receptor. https://doi.org/10.22541/au.176253891.19158813/v1
↑ "Temporary class drug order on benzofury and NBOMe compounds" . Retrieved 15 June 2015.
↑ "ACMD recommends permanent ban on two "legal highs"" . Retrieved 15 June 2015.
↑ "Ban on NBOMe and benzofurans comes into force" . Retrieved 15 June 2015.

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[1] Taschwer M, Hofer MG, Schmid MG (October 2014). "Enantioseparation of benzofurys and other novel psychoactive compounds by CE and sulfobutylether β-cyclodextrin as chiral selector added to the BGE". Electrophoresis. 35 (19): 2793–2799. doi:10.1002/elps.201400164. PMID 24930967. S2CID 2937770.

[StalbergaKronstrandSchranz2025-2] 1 2 Stalberga, D., Kronstrand, R., Schranz, B., van Zijl, N., Karlman, S., Aref, S., ... & Gréen, H. (2025). Comprehensive in vitro profiling of traditional and emerging stimulants at monoamine transporters and the 5HT2A receptor. https://doi.org/10.22541/au.176253891.19158813/v1

[3] "Temporary class drug order on benzofury and NBOMe compounds" . Retrieved 15 June 2015.

[4] "ACMD recommends permanent ban on two "legal highs"" . Retrieved 15 June 2015.

[5] "Ban on NBOMe and benzofurans comes into force" . Retrieved 15 June 2015.

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