Dapiprazole

Not to be confused with aripiprazole or brexpiprazole.

Dapiprazole

Clinical data
AHFS/Drugs.com	Consumer Drug Information
MedlinePlus	a601043
Pregnancy category	B
Routes of administration	Topical (eye drops)
ATC code	S01EX02 ( WHO )
Legal status
Legal status	In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability	Negligible when administered topically
Identifiers
IUPAC name 3-{2-[4-(2-methylphenyl)piperazin-1-yl]ethyl}-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,5-a]pyridine
CAS Number	72822-12-9  Y
PubChem CID	3033538
IUPHAR/BPS	7155
DrugBank	DB00298  Y
ChemSpider	2298190  Y
UNII	5RNZ8GJO7K
KEGG	D07775  Y
ChEBI	CHEBI:51066  Y
ChEMBL	ChEMBL1201216  N
CompTox Dashboard (EPA)	DTXSID90223140
Chemical and physical data
Formula	C19H27N5
Molar mass	325.460 g·mol−1
3D model (JSmol)	Interactive image
SMILES n1nc(n2c1CCCC2)CCN4CCN(c3ccccc3C)CC4
InChI InChI=1S/C19H27N5/c1-16-6-2-3-7-17(16)23-14-12-22(13-15-23)11-9-19-21-20-18-8-4-5-10-24(18)19/h2-3,6-7H,4-5,8-15H2,1H3 Y Key:RFWZESUMWJKKRN-UHFFFAOYSA-N Y
NY  (what is this?)    (verify)

Dapiprazole (brand name Rev-Eyes) is an alpha-1 blocker. It is used to reverse mydriasis after eye examination. ^[1]

References

1. Doughty MJ, Lyle WM (May 1992). "A review of the clinical pharmacokinetics of pilocarpine, moxisylyte (thymoxamine), and dapiprazole in the reversal of diagnostic pupillary dilation". Optometry and Vision Science. 69 (5): 358–68. doi:10.1097/00006324-199205000-00005. PMID   1350669. S2CID   22781280.