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Molar mass 209.67538
C02AC04 ( WHO )
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Tolonidine is an antihypertensive. [1] [2] [3]

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Moxonidine chemical compound

Moxonidine (INN) is a new-generation alpha-2/imidazoline receptor agonist antihypertensive drug licensed for the treatment of mild to moderate essential hypertension. It may have a role when thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or have failed to control blood pressure. In addition, it demonstrates favourable effects on parameters of the insulin resistance syndrome, apparently independent of blood pressure reduction. It is manufactured by Solvay Pharmaceuticals under the brand name Physiotens.

Camazepam chemical compound

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Doxefazepam chemical compound

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Econazole chemical compound

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Niaprazine chemical compound

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Zipeprol chemical compound

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Imidazoline receptors are the primary receptors on which clonidine and other imidazolines act. There are three main classes of imidazoline receptor: I1 is involved in inhibition of the sympathetic nervous system to lower blood pressure, I2 has as yet uncertain functions but is implicated in several psychiatric conditions, and I3 regulates insulin secretion.

Arylcyclohexylamine class of chemical compounds

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Caroxazone chemical compound

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Atiprosin chemical compound

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Fostedil chemical compound

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Tiamenidine chemical compound

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Litracen chemical compound

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Lortalamine chemical compound

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Fluperlapine chemical compound

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Valperinol chemical compound

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SL-164 chemical compound

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  1. Cosnier, D.; Duchene-Marullaz, P.; Grimal, J.; Rispat, G.; Streichenberger, G. (1975). "Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (Tolonidine), a new antihypertensive agent. I. Action on blood pressure and heart rate". Arzneimittel-Forschung. 25 (10): 1557–61. PMID   1243037.
  2. Cosnier, D.; Labrid, C.; Rispat, G.; Streichenberger, G. (1975). "Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. II. Action on cardiac contraction, circulatory parameters, autonomic receptors and diuresis". Arzneimittel-Forschung. 25 (11): 1802–6. PMID   1243090.
  3. Cosnier, D.; Hache, J.; Labrid, C.; Streichenberger, G. (1975). "Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. III. Action on the secretions of the digestive tract and on the central nervous system, acute toxicity". Arzneimittel-Forschung. 25 (12): 1926–33. PMID   3186.