Guanoxan

Last updated
Guanoxan
Guanoxan.png
Clinical data
ATC code
Identifiers
  • 2-(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)guanidine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C10H13N3O2
Molar mass 207.233 g·mol−1
3D model (JSmol)
  • c1ccc2c(c1)OCC(O2)CNC(=N)N
  • InChI=1S/C10H13N3O2/c11-10(12)13-5-7-6-14-8-3-1-2-4-9(8)15-7/h1-4,7H,5-6H2,(H4,11,12,13) X mark.svgN
  • Key:HIUVKVDQFXDZHU-UHFFFAOYSA-N X mark.svgN
 X mark.svgNYes check.svgY  (what is this?)    (verify)

Guanoxan is a sympatholytic drug that was marketed as Envacar by Pfizer in the UK to treat high blood pressure. It was not widely used and was eventually withdrawn from the market due to liver toxicity. [1] [2]

References

  1. ↑ Broadley KJ (1996). Autonomic Pharmacology. CRC Press. p. 276. ISBN   9780748405565.
  2. ↑ Wardell WM, Lasagna L (1975). Regulation and drug development . Washington: American Enterprise Institute for Public Policy Research. p.  65. ISBN   9780844731674.



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