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Routes of administration | Oral |
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Formula | C23H28N2O3 |
Molar mass | 380.488 g·mol−1 |
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Bopindolol (INN) is a beta blocker. It is an ester which acts as a prodrug for its active metabolite 4-(3-t-butylamino-2-hydroxypropoxy)-2-methylindole. [1]
Analysis of variance (ANOVA) is a collection of statistical models and their associated estimation procedures used to analyze the differences among means. ANOVA was developed by the statistician Ronald Fisher. ANOVA is based on the law of total variance, where the observed variance in a particular variable is partitioned into components attributable to different sources of variation. In its simplest form, ANOVA provides a statistical test of whether two or more population means are equal, and therefore generalizes the t-test beyond two means. In other words, the ANOVA is used to test the difference between two or more means.
In condensed matter physics, a Bose–Einstein condensate (BEC) is a state of matter that is typically formed when a gas of bosons at very low densities is cooled to temperatures very close to absolute zero. Under such conditions, a large fraction of bosons occupy the lowest quantum state, at which point microscopic quantum mechanical phenomena, particularly wavefunction interference, become apparent macroscopically. A BEC is formed by cooling a gas of extremely low density to ultra-low temperatures.
Gorillas are herbivorous, predominantly ground-dwelling great apes that inhabit the tropical forests of equatorial Africa. The genus Gorilla is divided into two species: the eastern gorilla and the western gorilla, and either four or five subspecies. The DNA of gorillas is highly similar to that of humans, from 95 to 99% depending on what is included, and they are the next closest living relatives to humans after chimpanzees and bonobos.
Paleontology, also spelled palaeontology or palæontology, is the scientific study of life that existed prior to, and sometimes including, the start of the Holocene epoch. It includes the study of fossils to classify organisms and study their interactions with each other and their environments. Paleontological observations have been documented as far back as the 5th century BC. The science became established in the 18th century as a result of Georges Cuvier's work on comparative anatomy, and developed rapidly in the 19th century. The term has been used since 1822 formed from Greek παλαιός, ὄν, and λόγος.
The Solar System is the gravitationally bound system of the Sun and the objects that orbit it. It formed 4.6 billion years ago from the gravitational collapse of a giant interstellar molecular cloud. The vast majority (99.86%) of the system's mass is in the Sun, with most of the remaining mass contained in the planet Jupiter. The planetary system around the Sun contains eight planets. The four inner system planets—Mercury, Venus, Earth and Mars—are terrestrial planets, being composed primarily of rock and metal. The four giant planets of the outer system are substantially larger and more massive than the terrestrials. The two largest, Jupiter and Saturn, are gas giants, being composed mainly of hydrogen and helium; the next two, Uranus and Neptune, are ice giants, being composed mostly of volatile substances with relatively high melting points compared with hydrogen and helium, such as water, ammonia, and methane. All eight planets have nearly circular orbits that lie near the plane of Earth's orbit, called the ecliptic.
A supernova is a powerful and luminous explosion of a star. A supernova occurs during the last evolutionary stages of a massive star or when a white dwarf is triggered into runaway nuclear fusion. The original object, called the progenitor, either collapses to a neutron star or black hole, or is completely destroyed to form a diffuse nebula. The peak optical luminosity of a supernova can be comparable to that of an entire galaxy before fading over several weeks or months.
The leopard is one of the five extant species in the genus Panthera, a member of the cat family, Felidae. It occurs in a wide range in sub-Saharan Africa, in some parts of Western and Central Asia, Southern Russia, and on the Indian subcontinent to Southeast and East Asia. It is listed as Vulnerable on the IUCN Red List because leopard populations are threatened by habitat loss and fragmentation, and are declining in large parts of the global range. The leopard is considered locally extinct in Hong Kong, Singapore, South Korea, Jordan, Morocco, Togo, the United Arab Emirates, Uzbekistan, Lebanon, Mauritania, Kuwait, Syria, Libya, Tunisia and most likely in North Korea, Gambia, Laos, Lesotho, Tajikistan, Vietnam and Israel. Contemporary records suggest that the leopard occurs in only 25% of its historical global range.
Panthera is a genus within the family Felidae that was named and described by Lorenz Oken in 1816 who placed all the spotted cats in this group. Reginald Innes Pocock revised the classification of this genus in 1916 as comprising the tiger, lion, jaguar, and leopard on the basis of common cranial features. Results of genetic analysis indicate that the snow leopard also belongs to the genus Panthera, a classification that was accepted by IUCN Red List assessors in 2008.
To help compare different orders of magnitude, the following lists describe various mass levels between 10−59 kg and 1052 kg. The least massive thing listed here is a graviton, and the most massive thing is the observable universe. Typically, an object having greater mass will also have greater weight (see mass versus weight), especially if the objects are subject to the same gravitational field strength.
Eumetazoa, also known as diploblasts, Epitheliozoa, or Histozoa, are a proposed basal animal clade as a sister group of the Porifera (sponges). The basal eumetazoan clades are the Ctenophora and the ParaHoxozoa. Placozoa is now also seen as a eumetazoan in the ParaHoxozoa.
In statistics, the Kendall rank correlation coefficient, commonly referred to as Kendall's τ coefficient, is a statistic used to measure the ordinal association between two measured quantities. A τ test is a non-parametric hypothesis test for statistical dependence based on the τ coefficient.
The R-type calcium channel is a type of voltage-dependent calcium channel. Like the others of this class, the α1 subunit forms the pore through which calcium enters the cell and determines most of the channel's properties. This α1 subunit is also known as the calcium channel, voltage-dependent, R type, alpha 1E subunit (CACNA1E) or Cav2.3 which in humans is encoded by the CACNA1E gene. They are strongly expressed in cortex, hippocampus, striatum, amygdala and interpeduncular nucleus.
Protein C-ETS2 is a protein that in humans is encoded by the ETS2 gene. The protein encoded by this gene belongs to the ETS family of transcription factors.
Protein CBFA2T1 is a protein that in humans is encoded by the RUNX1T1 gene.
Signaling lymphocytic activation molecule 1 is a protein that in humans is encoded by the SLAMF1 gene. Recently SLAMF1 has also been designated CD150.
Krueppel-like factor 11 is a protein that in humans is encoded by the KLF11 gene.
T-lymphocyte surface antigen Ly-9 is a protein that in humans is encoded by the LY9 gene. LY9 has also recently been designated CD229.
Colin Cooper is a British psychologist and was a senior lecturer in the School of Psychology at Queen's University Belfast until 2012, when he took early retirement and moved to Picton, and latterly London Ontario, Canada. Cooper also devised the multiple-choice IQ tests for the BBC television programme Test the Nation. Among the questions, Cooper said that he had managed to "sneak in a few things that interested me", including questions "exploring the link between intelligence and genetics, height and the number of accidents they have had."
Jean-Pierre Boissel is the co-founder and Chief Scientific Officer of Novadiscovery. He is an internationally recognized researcher in the field of therapeutic evaluation, cardiology and systems medicine. Emeritus Professor of Clinical Pharmacology, he is considered one of the founding fathers of systems medicine alongside Prof. Leroy Hood (US), Prof. Denis Noble (UK) and Prof. Charles Auffray (France).