Capsinolol

Last updated
Capsinolol
Capsinolol.svg
Clinical data
ATC code
  • none
Identifiers
  • N-{4-[2-Hydroxy-3-(isopropylamino)propoxy]-3-methoxybenzyl}nonanamide
CAS Number
PubChem CID
ChemSpider
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
Formula C23H40N2O4
Molar mass 408.583 g·mol−1
3D model (JSmol)
  • CCCCCCCCC(=O)NCC1=CC(=C(C=C1)OCC(CNC(C)C)O)OC
  • InChI=1S/C23H40N2O4/c1-5-6-7-8-9-10-11-23(27)25-15-19-12-13-21(22(14-19)28-4)29-17-20(26)16-24-18(2)3/h12-14,18,20,24,26H,5-11,15-17H2,1-4H3,(H,25,27)
  • Key:REOKPCLNKKXKDT-UHFFFAOYSA-N

Capsinolol is a beta blocker derived from nonivamide. It is the first beta blocker with an associated calcitonin gene-related peptide releasing activity in the heart. [1]

References

  1. ↑ Chen IJ, Yeh JL, Lo YC, Sheu SH, Lin YT (Sep 1996). "Capsinolol: the first beta-adrenoceptor blocker with an associated calcitonin gene-related peptide releasing activity in the heart". Br J Pharmacol. 119 (1): 7–14. doi:10.1111/j.1476-5381.1996.tb15670.x. PMC   1915742 . PMID   8872350.
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