2,5-Dimethoxy-4-methylphenylcyclopropylamine

Last updated
DMCPA
DMCPA.svg
DMCPA-3d-sticks.png
Clinical data
Other names25D-CPA; 2,5-Dimethoxy-4-methylphenylcyclopropylamine
Routes of
administration 		Oral [1]
Drug class Serotonin receptor modulator; Serotonergic psychedelic; Hallucinogen
ATC code
  • None
Identifiers
  • 2-(2,5-dimethoxy-4-methylphenyl)cyclopropan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
Formula C12H17NO2
Molar mass 207.273 g·mol−1
3D model (JSmol)
  • O(c1c(cc(OC)c(c1)C2CC2N)C)C
  • InChI=1S/C12H17NO2/c1-7-4-12(15-3)9(6-11(7)14-2)8-5-10(8)13/h4,6,8,10H,5,13H2,1-3H3 Yes check.svgY
  • Key:HYVPPECPQRBJEQ-UHFFFAOYSA-N Yes check.svgY
   (verify)

2,5-Dimethoxy-4-methylphenylcyclopropylamine (DMCPA) is a lesser-known psychedelic drug and a substituted amphetamine and phenylcyclopropylamine. [1] DMCPA was first synthesized by Alexander Shulgin.[ citation needed ]

Contents

Use and effects

In Alexander Shulgin's book PiHKAL (Phenethylamines I Have Known and Loved), the dose range is listed as 15 to 20 mg and the duration is listed as 4 to 8 hours. [1] DMCPA produces open-eye visuals, anorexia, and psychedelic dreams. [1] One of the reports in PiHKAL gave it a +++ on the Shulgin Rating Scale. [1]

Interactions

Pharmacology

The receptor interactions of DMCPA have been studied. [2]

Society and culture

United Kingdom

This substance is a Class A drug in the Drugs controlled by the UK Misuse of Drugs Act. [3]

See also

References

  1. 1 2 3 4 5 DMCPA Entry in PiHKAL
  2. ↑ Jain MK, Gumpper RH, Slocum ST, Schmitz GP, Madsen JS, Tummino TA, Suomivuori CM, Huang XP, Shub L, DiBerto JF, Kim K, DeLeon C, Krumm BE, Fay JF, Keiser M, Hauser AS, Dror RO, Shoichet B, Gloriam DE, Nichols DE, Roth BL (July 2025). "The polypharmacology of psychedelics reveals multiple targets for potential therapeutics" (PDF). Neuron. doi:10.1016/j.neuron.2025.06.012. PMID   40683247.
  3. ↑ "UK Misuse of Drugs act 2001 Amendment summary". Isomer Design. Archived from the original on 22 October 2017. Retrieved 12 March 2014.
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