Eticyclidine

Eticyclidine

Clinical data
ATC code	none
Legal status
Legal status	AU: S9 (Prohibited substance) BR: Class F2 (Prohibited psychotropics) [1] CA: Schedule III DE: Anlage I (Authorized scientific use only) UK: Class B US: Schedule I UN: Psychotropic Schedule I
Identifiers
IUPAC name N-Ethyl-1-phenylcyclohexylamine
CAS Number	2201-15-2  Y
PubChem CID	16622
ChemSpider	15759  Y
UNII	O8I1LL6A89
KEGG	C22716  Y
ChEMBL	ChEMBL279924  Y
CompTox Dashboard (EPA)	DTXSID2062248
Chemical and physical data
Formula	C14H21N
Molar mass	203.329 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCNC1(CCCCC1)C2=CC=CC=C2
InChI InChI=1S/C14H21N/c1-2-15-14(11-7-4-8-12-14)13-9-5-3-6-10-13/h3,5-6,9-10,15H,2,4,7-8,11-12H2,1H3 Y Key:IFYLVUHLOOCYBG-UHFFFAOYSA-N Y
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PCE (Eticyclidine, CI-400) is a dissociative anesthetic drug with hallucinogenic effects. It is similar in effects to phencyclidine but is slightly more potent. PCE was developed by Parke-Davis in the 1970s and evaluated for anesthetic potential under the code name CI-400, ^[2] but research into PCE was not continued after the development of ketamine, a similar drug with more favourable properties. ^[3] Due to its similarity in effects to PCP, PCE was placed into the Schedule 1 list of illegal drugs in the 1970s, although it was only briefly abused in the 1970s and 1980s and is now little known. ^[4]

See also

• Arylcyclohexylamine
• 3-MeO-PCE
• 3-MeO-PCP
• 4-MeO-PCP
• Phencyclidine
• PCPr
• Methoxetamine

References

1. Anvisa (2023-07-24). "RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-07-25). Archived from the original on 2023-08-27. Retrieved 2023-08-27.
2. Levy L, Cameron DE, Aitken RC (March 1960). "Observation on two psychotomimetic drugs of piperidine derivation--CI 395 (sernyl) and CI 400". The American Journal of Psychiatry. 116 (9): 843–844. doi:10.1176/ajp.116.9.843. PMID   14416411.
3. Kalir A, Edery H, Pelah Z, Balderman D, Porath G (May 1969). "1-Phenycycloalkylamine derivatives. II. Synthesis and pharmacological activity". Journal of Medicinal Chemistry. 12 (3): 473–477. doi:10.1021/jm00303a030. PMID   4977945.
4. Morris H, Wallach J (July 2014). "From PCP to MXE: a comprehensive review of the non-medical use of dissociative drugs". Drug Testing and Analysis. 6 (7–8): 614–632. doi:10.1002/dta.1620. PMID   24678061.