Eticlopride

Last updated
Eticlopride
Eticlopride.svg
Clinical data
ATC code
  • none
Identifiers
  • 5-chloro-3-ethyl-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-6-methoxybenzamide
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
Formula C17H25ClN2O3
Molar mass 340.85 g·mol−1
3D model (JSmol)
  • CCC1=CC(=C(C(=C1O)C(=O)NCC2CCCN2CC)OC)Cl
 X mark.svgNYes check.svgY  (what is this?)    (verify)

Eticlopride is a selective dopamine antagonist that acts on D2 dopamine receptor. It is primarily used in pharmacological research. [1] [2] [3] [4]

References

  1. ↑ "Eticlopride hydrochloride". Abcam.
  2. ↑ Claytor R, Lile JA, Nader MA (March 2006). "The effects of eticlopride and the selective D3-antagonist PNU 99194-A on food- and cocaine-maintained responding in rhesus monkeys". Pharmacology, Biochemistry, and Behavior. 83 (3): 456–64. doi:10.1016/j.pbb.2006.03.007. PMID   16631246. S2CID   39482275.
  3. ↑ Hemby SE, Smith JE, Dworkin SI (June 1996). "The effects of eticlopride and naltrexone on responding maintained by food, cocaine, heroin and cocaine/heroin combinations in rats". The Journal of Pharmacology and Experimental Therapeutics. 277 (3): 1247–58. doi:10.1016/S0022-3565(25)13070-X. PMID   8667185.
  4. ↑ Haile CN, Kosten TA (November 2001). "Differential effects of D1- and D2-like compounds on cocaine self-administration in Lewis and Fischer 344 inbred rats". The Journal of Pharmacology and Experimental Therapeutics. 299 (2): 509–18. doi:10.1016/S0022-3565(24)29257-0. PMID   11602661.
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.