Trifluoromethyldeschloroketamine

Last updated
Trifluoromethyldeschloroketamine
Trifluoromethyldeschloroketamine.svg
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
  • 2-(methylamino)-2-[2-(trifluoromethyl)phenyl]cyclohexan-1-one
CAS Number
PubChem CID
UNII
Chemical and physical data
Formula C14H16F3NO
Molar mass 271.283 g·mol−1
3D model (JSmol)
  • CNC1(CCCCC1=O)C2=CC=CC=C2C(F)(F)F
  • InChI=1S/C14H16F3NO/c1-18-13(9-5-4-8-12(13)19)10-6-2-3-7-11(10)14(15,16)17/h2-3,6-7,18H,4-5,8-9H2,1H3
  • Key:LETHPPJNGNSLDJ-UHFFFAOYSA-N

Trifluoromethyldeschloroketamine (TFMDCK) is a designer drug from the arylcyclohexylamine family, which is presumed to have similar properties to ketamine, a dissociative anesthetic drug with hallucinogenic and sedative effects. [1] It has been sold over the internet since around 2016, though genuine samples appear to be rare. [2] The o-trifluoromethyl analogue of hydroxynorketamine has also been researched as an antidepressant. [3]

See also

References

  1. ↑ Weber H, Drouvé N, Kortenbrede L, El Sheikh S. A Broadly Applicable Diels-Alder-Based Synthesis of Ketamine-Related Arylcyclohexylamines. J Org Chem. 2023 Aug 4;88(15):11372-11376. doi : 10.1021/acs.joc.3c01226 PMID   37463857
  2. ↑ Wallach J, Brandt SD (2018). "1,2-Diarylethylamine- and Ketamine-Based New Psychoactive Substances". New Psychoactive Substances. Handbook of Experimental Pharmacology. Vol. 252. pp. 305–352. doi:10.1007/164_2018_148. ISBN   978-3-030-10560-0. PMID   30196446.
  3. ↑ 种长效化合物的制备方法. Chinese patent CN 110540510A, 18 June 2019



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