DMeOB

Last updated
DMeOB
DMeOB structure.png
DMeOB 3D spacefill.png
Identifiers
  • 1-(3-methoxyphenyl)-N-[(3-methoxyphenyl)methylideneamino]methanimine
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
ECHA InfoCard 100.164.778 OOjs UI icon edit-ltr-progressive.svg
Chemical and physical data
Formula C16H16N2O2
Molar mass 268.316 g·mol−1
3D model (JSmol)
  • COc2cc(ccc2)C=NN=Cc1cccc(OC)c1
  • InChI=1S/C16H16N2O2/c1-19-15-7-3-5-13(9-15)11-17-18-12-14-6-4-8-16(10-14)20-2/h3-12H,1-2H3/b17-11+,18-12+ X mark.svgN
  • Key:FBNPHFBYHYNMHC-JYFOCSDGSA-N X mark.svgN
 X mark.svgNYes check.svgY  (what is this?)    (verify)

DMeOB is a drug used in scientific research which acts as a negative allosteric modulator of the metabotropic glutamate receptor subtype mGluR5. [1]

References

  1. O'Brien JA, Lemaire W, Chen TB, Chang RS, Jacobson MA, Ha SN, Lindsley CW, Schaffhauser HJ, Sur C, Pettibone DJ, Conn PJ, Williams DL (September 2003). "A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5". Molecular Pharmacology. 64 (3): 731–40. doi:10.1124/mol.64.3.731. PMID   12920211.