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Clinical data | |
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Other names | ADX-48621 |
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Chemical and physical data | |
Formula | C16H12FN3 |
Molar mass | 265.291 g·mol−1 |
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Dipraglurant (INN; development code ADX-48621) is a negative allosteric modulator of the mGlu5 receptor which is under development by Addex Therapeutics for the treatment of Parkinson's disease levodopa-induced dyskinesia (PD-LID). [1] [2] [3] As of 2014, it is in phase II clinical trials for this indication. [1] Addex Therapeutics is also investigating an extended-release formulation of dipraglurant for the treatment of non-parkinsonian dystonia. [4]