Methoxpropamine

Last updated
Methoxpropamine
Methoxpropamine.svg
Legal status
Legal status
Identifiers
  • 2-(3-Methoxyphenyl)-2-(propylamino)cyclohexanone
CAS Number
PubChem CID
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C16H23NO2
Molar mass 261.365 g·mol−1
3D model (JSmol)
  • COc1cccc(c1)C2(NCCC)CCCCC2=O
  • InChI=1S/C16H23NO2/c1-3-11-17-16(10-5-4-9-15(16)18)13-7-6-8-14(12-13)19-2/h6-8,12,17H,3-5,9-11H2,1-2H3
  • Key:AAVOSBAXDRASAH-UHFFFAOYSA-N

Methoxpropamine (MXPr, 2-Oxo-3'-methoxy-PCPr) is a dissociative anesthetic drug of the arylcyclohexylamine class and NMDA receptor antagonist [1] that is closely related to substances such as methoxetamine and PCPr. [2] It has been sold online as a designer drug, first being identified in Denmark in October 2019, [3] and is illegal in Finland. [4]

See also

References

  1. Irie T, Yamazaki D, Kikura-Hanajiri R (July 2021). "A potential of methoxpropamine to be a widespread recreational drug: it blocks NMDA receptors and inhibits NMDA receptor-mediated synaptic transmission in a brain preparation of mice". Forensic Toxicology. 39 (2): 474–80. doi:10.1007/s11419-021-00571-0. S2CID   232273277.
  2. Goncalves R, Castaing N, Richeval C, Ducint D, Titier K, Morvan E, et al. (April 2022). "Methoxpropamine (MXPr) in powder, urine and hair samples: Analytical characterization and metabolite identification of a new threat". Forensic Science International. 333: 111215. doi: 10.1016/j.forsciint.2022.111215 . PMID   35151938. S2CID   246685658.
  3. "EU Early Warning System Situation Report. Situation report 1" (PDF). European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). June 2020.
  4. "Valtioneuvoston asetus kuluttajamarkkinoilta kielletyistä psykoaktiivisista aineista" [Government decree on psychoactive substances banned from the consumer market]. Finlex Data Bank (in Finnish). Finnish Ministry of Justice.