FUB-144

Last updated
FUB-144
FUB-144 structure.png
Legal status
Legal status
Identifiers
  • [1-(4-Fluorobenzyl)-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C23H24FNO
Molar mass 349.449 g·mol−1
3D model (JSmol)
  • Fc1ccc(cc1)Cn1cc(c2c1cccc2)C(=O)C1C(C1(C)C)(C)C
  • InChI=1S/C23H24FNO/c1-22(2)21(23(22,3)4)20(26)18-14-25(19-8-6-5-7-17(18)19)13-15-9-11-16(24)12-10-15/h5-12,14,21H,13H2,1-4H3
  • Key:UXOFEILQVZFLRH-UHFFFAOYSA-N

FUB-144 (also known as FUB-UR-144) is an indole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor [1] and has been sold online as a designer drug. [2] It is an analogue of UR-144 and XLR-11 where the pentyl chain has been replaced with fluorobenzyl.

Contents

In the United States, FUB-144 was temporarily emergency scheduled by the DEA in 2019. [3] and made a permanent Schedule I Controlled Substance on April 7, 2022. [4]

Sweden's public health agency suggested classifying FUB-144 as hazardous substance on March 24, 2015. [5]

See also

References

  1. Marusich JA, Gamage TF, Zhang Y, Akinfiresoye LR, Wiley JL (October 2022). "In vitro and in vivo pharmacology of nine novel synthetic cannabinoid receptor agonists". Pharmacology, Biochemistry, and Behavior. 220 173467. doi:10.1016/j.pbb.2022.173467. PMC   9837865 . PMID   36154844.
  2. "FUB-144". Southern Association of Forensic Scientists. Archived from the original on 27 September 2015. Retrieved 23 July 2015.
  3. "Schedules of Controlled Substances: Temporary Placement of 5F-EDMB-PINACA, 5F-MDMB-PICA, FUB-AKB48, 5F-CUMYL-PINACA, and FUB-144 into Schedule I". Federal Register. 16 April 2019.
  4. "Schedules of Controlled Substances: Placement of 5F-EDMB-PINACA, 5FMDMB-PICA, FUB-AKB48, 5F-CUMYLPINACA, and FUB-144 in Schedule I" (PDF). Federal Register . 87 (67). 7 April 2022.
  5. "Fler ämnen föreslås bli klassade som narkotika eller hälsofarlig vara". Folkhälsomyndigheten. Retrieved 23 July 2015.