AB-PICA

AB-PICA
Legal status
Legal status	CA: Schedule II ; DE: NpSG (Industrial and scientific use only); UK: Class B ;
Identifiers
	IUPAC name N-[(1S)-1-(aminocarbonyl)-2-methylpropyl]-1-pentyl-1H-indole-3-carboxamide;
CAS Number	1801338-24-8 ; 1445583-48-1 (racemate);
PubChem CID	137332257 ;
ChemSpider	57427399 ;
UNII	BWQ0BJ2OGX ; Q71G788A6H ;
Chemical and physical data
Formula	C19H27N3O2
Molar mass	329.444 g·mol−1
3D model (JSmol)	Interactive image ;
	SMILES O=C(N[C@H](C(N)=O)C(C)C)C1=CN(CCCCC)C2=CC=CC=C21;
	InChI InChI=1S/C19H27N3O2/c1-4-5-8-11-22-12-15(14-9-6-7-10-16(14)22)19(24)21-17(13(2)3)18(20)23/h6-7,9-10,12-13,17H,4-5,8,11H2,1-3H3,(H2,20,23)(H,21,24)/t17-/m0/s1; Key:GOLDNQQANLFVSP-KRWDZBQOSA-N;

Last updated July 30, 2025

AB-PICA is a potent agonist for the CB₁ receptor (EC₅₀ = 12 nM) and CB₂ receptor (EC₅₀ = 12 nM).^[1]

References

↑ Banister SD, Moir M, Stuart J, Kevin RC, Wood KE, Longworth M, et al. (September 2015). "Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA". ACS Chemical Neuroscience. 6 (9): 1546–59. doi:10.1021/acschemneuro.5b00112. PMID 26134475.

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[1] Banister SD, Moir M, Stuart J, Kevin RC, Wood KE, Longworth M, et al. (September 2015). "Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA". ACS Chemical Neuroscience. 6 (9): 1546–59. doi:10.1021/acschemneuro.5b00112. PMID 26134475.

[1]

Legal status

Legal status	CA: Schedule II DE: NpSG (Industrial and scientific use only) UK: Class B
Identifiers
IUPAC name N-[(1S)-1-(aminocarbonyl)-2-methylpropyl]-1-pentyl-1H-indole-3-carboxamide
CAS Number	1801338-24-8 ^Y 1445583-48-1 (racemate)
PubChem CID	137332257
ChemSpider	57427399
UNII	BWQ0BJ2OGX Q71G788A6H ^Y
Chemical and physical data
Formula	C₁₉H₂₇N₃O₂
Molar mass	329.444 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(N[C@H](C(N)=O)C(C)C)C1=CN(CCCCC)C2=CC=CC=C21
InChI InChI=1S/C19H27N3O2/c1-4-5-8-11-22-12-15(14-9-6-7-10-16(14)22)19(24)21-17(13(2)3)18(20)23/h6-7,9-10,12-13,17H,4-5,8,11H2,1-3H3,(H2,20,23)(H,21,24)/t17-/m0/s1 Key:GOLDNQQANLFVSP-KRWDZBQOSA-N

AB-PICA

See also

References