Mycobacterium microti

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Mycobacterium microti
Scientific classification
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Species:
M. microti
Binomial name
Mycobacterium microti
Reed 1957, ATCC 19422

Mycobacterium microti is a member of the Mycobacterium tuberculosis complex (MTBC) known as the 'Vole bacillus', first described as a pathogen of field voles in England. [1]

Contents

Description

Gram-positive, nonmotile, acid-fast rods.

Colony characteristics

Physiology

Differential characteristics

Commercially available nucleic acid hybridisation assays are widely used to identify members of the M. tuberculosis complex..

Differentiation between individual members of the M tuberculosis complex is possible using a variety of molecular techniques, and individual strains within a species may be further distinguished using a variety of molecular typing methods.

Pathogenesis

Cause of naturally acquired generalized tuberculosis in voles and other mammals, including cats and new world camelids such as llamas. Human infections are rare, but do occur in both immunocompromised and apparently immunocompetent patients. [2] [3]

Type strain

Strain ATCC 19422 = CIP 104256 = NCTC 8710.

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References

  1. Wells, A Q (1937). "Tuberculosis in wild voles". Lancet. 229 (5934): 1221. doi:10.1016/S0140-6736(00)83505-9. S2CID   2364438.
  2. Emmanuel, FX (Dec 2007). "Human and animal infections with Mycobacterium microti, Scotland". Emerg Infect Dis. 13 (12): 1924–1927. doi:10.3201/eid1312.061536. PMC   2876740 . PMID   18258049 . Retrieved 26 August 2015.
  3. van Soolingen, D (Jul 1998). "Diagnosis of Mycobacterium microti infections among humans by using novel genetic markers". J Clin Microbiol. 36 (7): 1840–5. doi:10.1128/JCM.36.7.1840-1845.1998. PMC   104938 . PMID   9650922.