National Institute of Nutrition, Hyderabad

Last updated

ICMR - National Institute of Nutrition
National Institute of Nutrition, Hyderabad Logo.png
National Institute of Nutrition, Hyderabad.jpg
Established1918 (Coonoor)
1958 (Hyderabad)
Research type Public
Budget ₹ 6.43 billion (US$81 million)
Field of research
 Nutrition
Micronutrients
Director Dr. R. Hemalatha
AddressJamai-Osmania
Location Tarnaka, Hyderabad
Campus Urban
Affiliations K.N.R.U.H.S.
N.T.R.U.H.S.
University of Hyderabad
Osmania University
Operating agency
 ICMR
Website www.nin.res.in

The National Institute of Nutrition (NIN) is an Indian public health, nutrition and translational research centre located in Hyderabad, India. [1] [2] The institute is one of the oldest research centres in India, and the largest centre, under the Indian Council of Medical Research, located in the vicinity of Osmania University. The institute has associated clinical and paediatric nutrition research wards at various hospitals such as the Niloufer Hospital for Women and Children, the Government Maternity Hospital, the Gandhi Medical College and the Osmania General Hospital in Hyderabad.

Contents

The National Centre for Laboratory Animal Science (to be integrated into the National Animal Resource Facility for Biomedical Research ), the Food and Drug Toxicology Research Centre, the National Nutrition Monitoring Bureau are the other wings of NIN, [3] for India's Ministry of Health and Family Welfare. [4] The institute also derives funding from the Indian Department of Biotechnology. The institute majorly conducts research in obesity, [5] [6] diabetes, food chemistry, dietetics, clinical toxicology, and micronutrient deficiency [7] [8] in collaboration with centres such as the Rockefeller University, University of Colorado School of Medicine, Washington University School of Medicine, and the Johns Hopkins Bloomberg School of Public Health in the US, [9] [10] [11] and the University of Wollongong in Australia. [12] [13]

History

Pasteur Institute at Coonoor in 1927 PasteurInstituteCoonoor.jpg
Pasteur Institute at Coonoor in 1927
NIN at Hyderabad Image of NIN.jpg
NIN at Hyderabad

The institute was founded in 1918 by Sir Robert McCarrison. It was originally a single room laboratory at the Pasteur Institute, Coonoor, Tamil Nadu for the study of Beriberi, and was called the Beri-Beri Enquiry Unit. [14] McCarrison was invalided to Britain from 1920–1922, and in 1923 the enquiry was axed on financial grounds. It was restored two years later as the Deficiency Disease Inquiry, which McCarrison headed from 1925–1929. [15] The scope of the laboratory expanded to include all deficiency diseases, and around 1928–1929 became the Nutrition Research Laboratories (NRL), with McCarrison as its first director, until his retirement in 1935, when he was succeeded by Dr. W.R. Ackroyd. [14] [15] [16] The facility moved to Hyderabad in 1958 and in 1969 was renamed the National Institute of Nutrition. [14]

Research

High-throughput sequencing platform - Molecular Biology NIN hyderabad NGS platform.jpg
High-throughput sequencing platform – Molecular Biology
Flow cytometry - Immunology BD FACS ARIA II NIN, Hyderabad.jpg
Flow cytometry – Immunology
Primate Experimental Medicine & Surgery Unit NCLAS - NIN primate surgery unit.jpg
Primate Experimental Medicine & Surgery Unit
National Center for Laboratory Animal Sciences ICMR - NIN - NCLAS.jpg
National Center for Laboratory Animal Sciences
Microscopy - Biochemistry Microscopy at National Institute of Nutrition, Hyderabad.jpg
Microscopy – Biochemistry
Confocal Microscopy - Biochemistry Confocal microscopy at NIN.jpg
Confocal Microscopy – Biochemistry

The institute carries out research and patent development in clinical nutrition, outcomes research, pharmacology, [17] pathology, toxicology, food chemistry, [18] endocrinology, [8] molecular biology, [19] regenerative medicine, [20] [21] community nutrition, [22] [23] ophthalmology, [24] and sports nutrition. [25] [26] Agencies such as WHO and FAO recognised the institute as a Centre for excellence in food quality, safety and nutrition research. [27] [28] [29] [30] [31]

The institute is equipped with facilities including animal housing, In vivo imaging, automated electrophoresis, flow cytometry, DNA Microarray, liquid chromatography–mass spectrometry, atomic absorption spectroscopy, matrix-assisted laser desorption/ionization, scanning electron microscope, confocal laser scanning microscopy, Transmission electron microscopy, DNA sequencers, cryogenic equipment, thermal cyclers, etc. [32] [33] [34]

National Centre for Laboratory Animal Sciences

The National Centre for Laboratory Animal Sciences (NCLAS) was established in India in 1957 for spreading knowledge on Care, Breeding, Management and Experimentation using laboratory animals in biomedical research. It started as a unit called Laboratory Animal Information Service (LAIS) at the Indian Cancer Research Centre, Bombay, in 1957 and this unit was later shifted to National Institute of Nutrition (NIN), Hyderabad in 1976. it was renamed then as Laboratory Animal Information Service Centre (LAISC). In 1998, during the 7th Five Year Plan, additional support came from Department of Biotechnology (DBT) under the Ministry of Science and Technology, Government of India, which helped the unit to become the NCLAS. On 5 January 2016, the NCLAS is merged with NARF-BR and the former Unit becomes the NIN-animal facility. [35] The scientists of NCLAS Developed obese and diabetic mutant rat models: WNIN/GR-Ob, WNIN/Ob, WNIN/Ob-IGT, to serve as pre-clinical animal models in drug development for chronic diseases like Obesity and Diabetes. Established a state of the art non-human primate facility with provision for experiments based on monkeys. [33] [34] NCLAS also came into the limelight due to the WNIN/Ob obese rat strain which is the heaviest inbred rat model available. [5] It has been reported to reach up to 1.47 kg in body weight [36] and shows various signs of increased DNA damage and significantly decreased lifespan. [6]

NIN and FSSAI

The Food Safety and Standards Authority of India (FSSAI) largely sources science-based knowledge and information for formulating the food regulations in the country. Many scientists of NIN are a part of various committee, panels and scientific groups that guide the FSSAI. The director is the co-chair of the three member panel that is looking into upcoming the front-of-pack labelling regulations. [37] The FSSAI is responsible for protecting and promoting public health through the regulation and supervision of food safety. [37] The FSSAI has been established under the Food Safety and Standards Act, 2006 which is a consolidating statute related to food safety and regulation in India. [37]

Education

NIN offers advanced education courses and MS-MD-PhD program(s) for nutrition, biochemistry, dietetics and laboratory animal sciences. The Centre is recognised by Dr. N.T.R. University of Health Sciences and Kaloji Narayana Rao University of Health Sciences for pursuing post graduation in Applied Nutrition. Recently NIN has started awarding Research Fellowships to the toppers in the MSc course to pursue PhD in the institution. The institute is well recognised by Osmania University, University of Hyderabad, Jawaharlal Nehru Technological University, for pursuing PhD in various streams of Life Sciences especially Biochemistry and Nutrition. The institute has trained over 1600 health professionals from more than 35 countries. More than 150 candidates have successfully obtained PhD and MD degrees from NIN.

Achievements

See also

Related Research Articles

<span class="mw-page-title-main">Health in India</span> Overview of health in India

India's population in 2021 as per World Bank is 1.39 billion. Being the world's second-most-populous country and one of its fastest-growing economies, India experiences both challenges and opportunities in context of public health. India is a hub for pharmaceutical and biotechnology industries; world-class scientists, clinical trials and hospitals yet country faces daunting public health challenges like child undernutrition, high rates of neonatal and maternal mortality, growth in noncommunicable diseases, high rates of road traffic accidents and other health related issues.

<span class="mw-page-title-main">Genome Valley</span> Science Parks

Genome Valley is an Indian high-technology business district spread across 2,000-acre (8.1 km2)/(3.1 sq mi) in Hyderabad, India. It is located across the suburbs, Turakapally, Shamirpet, Medchal, Uppal, Patancheru, Jeedimetla, Gachibowli and Keesara. The Genome Valley has developed as a cluster for Biomedical research, training and manufacturing. Genome Valley is now into its Phase III, which is about 11 kms from the Phase I and II with the total area approximately 2,000-acre (8.1 km2).

<span class="mw-page-title-main">Centre for Cellular and Molecular Biology</span>

The Centre for Cellular and Molecular Biology or CCMB is an Indian fundamental life science research establishment located in Hyderabad that operates under the aegis of the Council of Scientific and Industrial Research. CCMB is a designated "Centre of Excellence" by the Global Molecular and Cell Biology Network, UNESCO.

<span class="mw-page-title-main">Indian Council of Medical Research</span> Government organization

The Indian Council of Medical Research (ICMR), the apex body in India for the formulation, coordination and promotion of biomedical research, is one of the oldest and largest medical research bodies in the world.

<span class="mw-page-title-main">Jeffrey M. Friedman</span>

Jeffrey M. Friedman is a molecular geneticist at New York City's Rockefeller University and an Investigator of the Howard Hughes Medical Institute. His discovery of the hormone leptin and its role in regulating body weight has had a major role in the area of human obesity. Friedman is a physician scientist studying the genetic mechanisms that regulate body weight. His research on various aspects of obesity received national attention in late 1994, when it was announced that he and his colleagues had isolated the mouse ob gene and its human homologue. They subsequently found that injections of the encoded protein, leptin, decreases body weight of mice by reducing food intake and increasing energy expenditure. Current research is aimed at understanding the genetic basis of obesity in human and the mechanisms by which leptin transmits its weight-reducing signal.

<span class="mw-page-title-main">International Life Sciences Institute</span>

The International Life Sciences Institute (ILSI) is a global nonprofit 501(c)(3) organization headquartered in Washington, DC, United States that publishes peer-reviewed studies on nutrition and food safety. It was founded in 1978 by Alex Malaspina, a former Coca-Cola executive, and it is partially financed by its 300+ members, which includes food and chemical corporations like BASF, McDonald’s, Syngenta and Pepsi. In 2020, the organization's revenue was $10.1 million.

The National Institute of Virology in Pune, India is an Indian virology research institute and part of the Indian Council of Medical Research (ICMR). It was previously known as 'Virus Research Centre' and was founded in collaboration with the Rockefeller Foundation. It has been designated as a WHO H5 reference laboratory for SE Asia region.

The Department of Biotechnology (DBT) is an Indian government department, under the Ministry of Science and Technology responsible for administrating development and commercialisation in the field of modern biology and biotechnology in India. It was set up in 1986.

Despite India's 50% increase in GDP since 2013, more than one third of the world's malnourished children live in India. Among these, half of the children under three years old are underweight.

<span class="mw-page-title-main">Robert McCarrison</span> Irish physician and nutritionist

Major-General Sir Robert McCarrison, CIE, FRCP was a Northern Ireland physician and nutritionist in the Indian Medical Service, who was made a Companion of the Indian Empire (CIE) in 1923, received a knighthood in July 1933, and was appointed as Honourable Physician to the King in 1935.

<span class="mw-page-title-main">Coluthur Gopalan</span> Indian nutritionist (1918–2019)

Coluthur Gopalan FRCP, FRS, FAMS, FASc was an Indian nutritionist. He was responsible for initiating nutrition research in independent India, leading to a number of interventions such as the Integrated Child Development Services, the midday meal scheme for school children, goiter prevention programme, etc. The burning feet syndrome is also known as Grierson-Gopalan syndrome. While the condition was described in 1826 by a British medical officer James Grierson, Gopalan also described this condition in 1946 when he observed it, "chiefly in females between the ages of 20 and 40 years, among the poor in South India".

<span class="mw-page-title-main">Food Safety and Standards Authority of India</span> Government body in India

Food Safety and Standards Authority of India (FSSAI) is a statutory body established under the Ministry of Health & Family Welfare, Government of India. The FSSAI has been established under the Food Safety and Standards Act, 2006, which is a consolidating statue related to food safety and regulation in India. FSSAI is responsible for protecting and promoting public health through the regulation and supervision of food safety.

The National Animal Resource Facility for Biomedical Research is an Indian Biomedical research facility, and vivarium under the Indian Council of Medical Research. The new 33rd flagship institute of ICMR was founded in 2015, at Genome Valley in Hyderabad, India. The center is a state of the art Animal house and Animal sciences facility located near Turkapally, Shamirpet spread over 102 acres of land.

<span class="mw-page-title-main">Central Institute of Fisheries Technology</span> Research center in Kochi, India

The Central Institute of Fisheries Technology (CIFT) is an autonomous organization established by the government of India, engaged in research related to fishing and fish processing in the country. The institute has its headquarters in Matsyapuri, Willingdon Island, Kochi and is a subsidiary of Indian Council of Agricultural Research (ICAR), New Delhi, under the Ministry of Agriculture, India.

Kamala Krishnaswamy is an Indian scientist in nutrition. She is the former director of the National institute of Nutrition. She was also president of the Nutrition Society of India.

Undurti Narasimha Das shortly Undurti N. Das and U. N. Das is an Indian clinical immunologist, endocrinologist and the founder president and chief executive officer of UND Life Sciences. Additionally, he serves as the Chief Medical Officer and the Chairman of the Scientific Advisory Board of Asha Nutrition Sciences, Inc. An elected fellow of the National Academy of Medical Sciences, Das is known for his researches in the fields of Immunology, Endocrinology and Rheumatology. He holds a number of patents for his work The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 1992.

<span class="mw-page-title-main">Pasteur Institute of India</span>

Pasteur Institute of India, Coonoor is one of the pioneer institutes in India in the production of Anti Rabies Vaccine and DPT vaccine for the Expanded Programme of Immunization of Government of India. This institute started functioning as Pasteur Institute of Southern India, on 6 April 1907 and was officially opened by H. E. Sir Arthur Lawley, Governor of Madras, on 25 April 1907. The first President of the Society is Surgeon-General W.R. Browne, C.I.E., I.M.S., Surgeon-General with the Government of Madras. The first Honorary Secretary cum Director is Captain J.W. Cornwall, I.M.S., in his remembrance, the road starting from the adjacent area of main gate of the Pasteur Institute of India to Alwarpet named as Cornwall Road. The institute later renamed as Pasteur Institute of India and started functioning as an autonomous body under the Ministry of Health and Family Welfare, Government of India, from 10 February 1977. The affairs of the institute are managed by a governing body.

<span class="mw-page-title-main">Harsh Vardhan Batra</span> Indian scientist (born 1955)

Harsh Vardhan Batra is an Indian scientist working in animal biotechnology at the Department of Biotechnology (DBT), of the Indian Ministry of Science and Technology. He is a former director of the Defence Food Research Laboratory (DFRL), a Defence Research and Development Organisation (DRDO) establishment at Mysore. As a specialist in infectious diseases, he participated in the DRDO biodefence preparedness program, and was an expert member of the technical advisory committee on plague constituted by the government of India in September 1994. He served as technical consultant for the design and construction of high containment laboratories for DRDO, the Indian Council for Agricultural Research (ICAR) and Indian Council of Medical Research (ICMR). He participated in the United Nations Biological Weapons Convention (BTWC) ad hoc group meetings in Geneva as a member of the Indian delegation, and conducted World Health Organization (WHO) Southeast Asia Regional Office meetings and workshops on infectious diseases.

References

  1. ↑ Bhargava, Pushpa M (12 November 2011). "Could they buy salt and spices, fuel and milk, and pay rent... with Rs. 2.33 a day?". The Hindu. Chennai, India.
  2. ↑ "International Conference on Translational Research" (PDF). Retrieved 21 August 2012.
  3. ↑ About ICMR, Indian Council of Medical Research, retrieved 15 August 2010 ICMR's Institutes/Centres Archived 7 June 2015 at the Wayback Machine (scroll down page to find NIN)
  4. ↑ Special Correspondent (11 October 2012). "NATIONAL / ANDHRA PRADESH : Governor for review of PDS". The Hindu. Chennai, India. Retrieved 7 December 2012.
  5. 1 2 K. S. Jayaraman (2005). "'Sumo' rats set researchers on hunt for obesity genes". Nature Medicine. 11 (2): 108. doi: 10.1038/nm0205-108a . PMID   15692582. S2CID   5424331.
  6. 1 2 Sinha, Jitendra Kumar; Ghosh, Shampa; Swain, Umakanta; Giridharan, Nappan Veethil; Raghunath, Manchala (2014). "Increased macromolecular damage due to oxidative stress in the neocortex and hippocampus of WNIN/Ob, a novel rat model of premature aging". Neuroscience. 269: 256–264. doi:10.1016/j.neuroscience.2014.03.040. PMID   24709042. S2CID   9934178.
  7. ↑ Venu, L; Harishankar, N; Krishna, T. P.; Raghunath, M (2004). "Does maternal dietary mineral restriction per se predispose the offspring to insulin resistance?". European Journal of Endocrinology. 151 (2): 287–94. doi: 10.1530/eje.0.1510287 . PMID   15296486.
  8. 1 2 Ghosh S, Sinha JK, Putcha UK, Raghunath M (2016). "Severe but Not Moderate Vitamin B12 Deficiency Impairs Lipid Profile, Induces Adiposity, and Leads to Adverse Gestational Outcome in Female C57BL/6 Mice". Frontiers in Nutrition. 3 (1): 1–10. doi: 10.3389/fnut.2016.00001 . PMC   4722109 . PMID   26835453.
  9. ↑ Fernandez-Rao, Sylvia; Hurley, Kristen M.; Nair, Krishnapillai Madhavan; Balakrishna, Nagalla; Radhakrishna, Kankipati V.; Ravinder, Punjal; Tilton, Nicholas; Harding, Kimberly B.; Reinhart, Greg A.; Black, Maureen M. (2014). "Integrating nutrition and early child-development interventions among infants and pre-schoolers in rural India". Annals of the New York Academy of Sciences. 1308 (1): 218–231. Bibcode:2014NYASA1308..218F. doi: 10.1111/nyas.12278 . PMID   24673168.
  10. ↑ "National conference on nutrition security at NIN, Hyderabad – The Times of India". The Times of India.
  11. ↑ "Mice to reveal key to human obesity". The Times of India . Archived from the original on 16 June 2013.
  12. ↑ "Australia-India food research partnerships on the menu – News & Media @ UOW". Media.uow.edu.au. 27 March 2008. Retrieved 1 September 2012.{{cite journal}}: Cite journal requires |journal= (help)
  13. ↑ "Director in charge of NIN". The Hindu. 31 August 2012. Retrieved 3 September 2012.
  14. 1 2 3 Down the memory lane, National Institute of Nutrition, Hyderabad, India, retrieved 12 August 2010
  15. 1 2 Arnold, David (2000), Science, technology, and medicine in Colonial India, The New Cambridge History of India. Part III, Volume 5, Cambridge, UK: Cambridge University Press, pp. 201, 215, ISBN   978-0-521-56319-2 , retrieved 12 August 2010
  16. ↑ NIN origins (28 May 1960), "Obituary: Sir ROBERT McCARRISON, C.I.E., M.D., D.Sc. L.L.D., F.R.C.P", British Medical Journal, 1 (5186): 1663–1664, doi:10.1136/bmj.1.5186.1663, PMC   1967996 , PMID   13856887 , retrieved 10 August 2010
  17. ↑ "Pyridoxal 5' phosphate protects islets against streptozotocin-induced beta-cell dysfunction – in vitro and in vivo". Ebm.rsmjournals.com. 4 April 2011. Retrieved 30 August 2012.{{cite journal}}: Cite journal requires |journal= (help)
  18. ↑ T. Longvah; Y.G. Deosthale; P. Uday Kumar (2000). "Nutritional and short term toxicological evaluation of Perilla seed oil". Food Chemistry. 70: 13–16. doi:10.1016/S0308-8146(99)00263-0.
  19. ↑ Dutta, R. C. (24 May 2012). "In search of optimal scaffold for regenerative medicine and therapeutic delivery". Ther Deliv. 2 (2): 231–4. doi:10.4155/tde.10.100. PMID   22833949.
  20. ↑ Rajarathna (2010). "advancements in stem cell research: an Indian perspective-II | T". Annals of Neurosciences. 17 (3): 110–112. doi:10.5214/ans.0972-7531.1017303. PMC   4116989 . PMID   25205885 . Retrieved 30 August 2012.
  21. ↑ Tissue and Cell, v.43, no.4, 2011 August, p.266(5) ( ISSN   0040-8166)
  22. ↑ "Hyderabad to host national meet on diet". The Times of India . 11 April 2012. Archived from the original on 16 October 2013.
  23. ↑ "Landes Bioscience Journals: Islets". Landesbioscience.com. Retrieved 21 August 2012.
  24. ↑ "A novel mutation (F71L) in αA-Crystallin with defective chaperone-like function associated with age-related cataract" . Retrieved 1 September 2012.{{cite journal}}: Cite journal requires |journal= (help)
  25. ↑ "Nutrition and Hydration guidelines for excellence in sports" (PDF). Retrieved 21 August 2012.
  26. ↑ "Nagaland News | Current News | Latest News | Breaking News – India: Olympic Medals?". The Morung Express. Retrieved 21 August 2012.
  27. ↑ "NIN introduces indigenous developed cost effective pathogen detection kit". Pharmabiz.com. Retrieved 21 August 2012.
  28. ↑ "NIN bags 'City Strategist' award". The Hindu . Chennai, India. 26 April 2010. Archived from the original on 1 May 2010.
  29. ↑ "National Institute of Nutrition develops food contamination detection kits". The Times of India . 27 April 2012. Archived from the original on 4 January 2013. Retrieved 21 August 2012.
  30. ↑ "Leadership in Nutrition" (PDF). Retrieved 21 August 2012.
  31. ↑ Patent file No.IPD/PA/96022/97 Microbiological Identification kit.
  32. ↑ "National Institute of Nutrition Hyderabad". Icmr.nic.in. Retrieved 21 August 2012.
  33. 1 2 "Annual Report 2007–2008" (PDF). Indian Council of Medical Research. Retrieved 21 August 2012.
  34. 1 2 "Analysis of Reproductive Health, ICMR" (PDF). Retrieved 21 August 2012.
  35. ↑ NARF-BR, ICMR. "NCLAS". NARF-BR. Retrieved 3 October 2019.
  36. ↑ Sinha, Jitendra Kumar; Giridharan, Nappan Veethil; Raghunath, Manchala (2012). "Can systemic and central IGF1 and BDNF levels play a role in decreasing the longevity of WNIN obese mutant rats?". International Journal of Developmental Neuroscience. 30 (8): 648–49. doi:10.1016/j.ijdevneu.2012.03.253. S2CID   221849429.
  37. 1 2 3 "About FSSAI > Introduction". Archived from the original on 2 April 2012. Retrieved 29 April 2012.
  38. ↑ "Tata group – Tata Chemicals – Media releases – India's first iodine plus iron fortified salt launched by Tata Chemicals". tata.com. Archived from the original on 6 February 2013. Retrieved 8 June 2013.

Nutrition Content in Food Items, Anurag Mishra, Jagran Prime []

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.