Roxana Moslehi is an Iranian-born genetic epidemiologist.
Genetic epidemiology is the study of the role of genetic factors in determining health and disease in families and in populations, and the interplay of such genetic factors with environmental factors. Genetic epidemiology seeks to derive a statistical and quantitative analysis of how genetics work in large groups.
Sir Bruce Anthony John Ponder FMedSci FAACR FRS FRCP is an English geneticist and cancer researcher. He is Emeritus Professor of Oncology at the University of Cambridge and former director of the Cancer Research UK Cambridge Institute and of the Cancer Research UK Cambridge Cancer Centre.
Stephen Jacob Chanock is an American physician and geneticist. He currently serves as Director of the Division of Cancer Epidemiology and Genetics at the U.S. National Cancer Institute (NCI).
In genetics, a polygenic score (PGS) is a number that summarizes the estimated effect of many genetic variants on an individual's phenotype. The PGS is also called the polygenic index (PGI) or genome-wide score; in the context of disease risk, it is called a polygenic risk score or genetic risk score. The score reflects an individual's estimated genetic predisposition for a given trait and can be used as a predictor for that trait. It gives an estimate of how likely an individual is to have a given trait based only on genetics, without taking environmental factors into account; and it is typically calculated as a weighted sum of trait-associated alleles.
Douglas F. Easton FMedSci is a British epidemiologist who conducts research on the genetics of human cancers. He is Professor of Genetic Epidemiology and Centre for Cancer Genetic Epidemiology at the University of Cambridge. He founded Cambridge's Cancer Research UK Genetic Epidemiology Unit in 1995, and was a Principal Research Fellow there from 2001 to 2011. He is a Professorial Fellow of Homerton College, Cambridge.
Bhramar Mukherjee is an Indian-American biostatistician, data scientist, professor and researcher. She is the John D. Kalbfleisch Distinguished University Professor of Biostatistics, Siobán D. Harlow Collegiate Professor of Public Health and the Chair of Department of Biostatistics, a professor of epidemiology and global public health at the University of Michigan. She serves as the associate director for Quantitative Data Sciences at University of Michigan Rogel Cancer Center. Mukherjee holds a Senior Honorary Visiting Fellow position at the Biostatistics Unit of the Medical Research Council, working on the theme of population health at the University of Cambridge, UK. She has served as the past Chair for Committee of Presidents of Statistical Societies (COPSS) for a three-year term 2019-2021.
Montserrat García-Closas, M.D., M.P.H., Dr.P.H., is a Spanish researcher and academic who is best known for her works on identifying cancer biomarkers and genetic susceptibility to cancer. Dr. García-Closas serves as the deputy director of the Division of Cancer Epidemiology & Genetics (DCEG) of the National Cancer Institute, as well as the Acting Chief of the Integrative Tumor Epidemiology Branch of the DCEG.
Xiaohong Rose Yang is an American biomedical scientist researching the genetics of dysplastic nevus syndrome and chordoma, and etiologic heterogeneity of breast cancer. She is a senior investigator at the National Cancer Institute. Yang leads breast cancer studies in mainland China, Hong Kong, and Malaysia.
Stephanie J. London is an American epidemiologist and physician-scientist specializing in environmental health, respiratory diseases, and genetic susceptibility. She is the deputy chief of the epidemiology branch at the National Institute of Environmental Health Sciences.
Transcriptome-wide association study (TWAS) is a genetic methodology that can be used to compare the genetic components of gene expression and the genetic components of a trait to determine if an association is present between the two components. TWAS are useful for the identification and prioritization of candidate causal genes in candidate gene analysis following genome-wide association studies. TWAS looks at the RNA products of a specific tissue and gives researchers the abilities to look at the genes being expressed as well as gene expression levels, which varies by tissue type. TWAS are valuable and flexible bioinformatics tools that looks at the associations between the expressions of genes and complex traits and diseases. By looking at the association between gene expression and the trait expressed, genetic regulatory mechanisms can be investigated for the role that they play in the development of specific traits and diseases.
Katrina A. Blouke Goddard is an American genetic epidemiologist and biostatistician specializing in public health genomics and the translation of genomic applications into clinical practice. Goddard is the director of the division of cancer control and population sciences (DCCPS) at the National Cancer Institute (NCI). She was previously the distinguished investigator and director of translational and applied genomics at the Kaiser Permanente Center for Health Research and a faculty member at Case Western Reserve University.
Rachael Zoe Stolzenberg-Solomon is an American epidemiologist and dietitian. She is a senior investigator and head of the metabolic epidemiology branch at the National Cancer Institute.
Patricia A. Hartge is an American cancer epidemiologist who conducted genome-wide association studies on ovarian cancer, non-Hodgkin lymphoma, melanoma, and other malignancies. From 1996 to 2013, Hartge was deputy director of the epidemiology and biostatistics program in the division of cancer epidemiology and genetics at the National Cancer Institute.
Hannah P. Yang is an American cancer epidemiologist who is a staff scientist and associate director of scientific operations in the National Cancer Institute's division of cancer epidemiology and genetics.
Maria Teresa Landi is an Italian epidemiologist and oncologist who researches genetic and environmental determinants of lung cancer and melanoma. At the National Cancer Institute, she is a senior investigator in the integrative tumor epidemiology branch and a senior advisor for genomic epidemiology. Landi is an associate professor of epidemiology at the Johns Hopkins Bloomberg School of Public Health.
Ruth Maria Pfeiffer is a biostatistician who researches risk prediction, molecular and genetic epidemiology, and electronic medical records. She is a senior investigator in the biostatistics branch at the National Cancer Institute. Pfeiffer is an elected member of the International Statistical Institute and the American Statistical Association.
Aimée Rebecca Kreimer is an American cancer epidemiologist who researches the etiology and prevention of human papillomavirus infection (HPV) and cancer prevention. She is a senior investigator in the infections and immunoepidemiology branch at the National Cancer Institute.
Ludmila Prokunina-Olsson is a molecular medical geneticist who conducts genetic and functional analyses downstream of genome-wide association studies (GWAS) for various human traits, including cancer, immune and infectious diseases. She is chief of the Laboratory of Translational Genomics (LTG) at the National Cancer Institute.
Sonja Ingrid Berndt is an American pharmacologist and cancer epidemiologist who researches non-Hodgkin lymphoma, prostate cancer, and anthropometric traits that are cancer risk factors. She is a senior investigator in the occupational and environmental epidemiology branch at the National Cancer Institute.
