Nitric oxide reductase (menaquinol)

Nitric oxide reductase (menaquinol)
Identifiers
EC no.	1.7.5.2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Nitric oxide reductase (menaquinol) (EC 1.7.5.2) is an enzyme. ^{[1] [2] [3]} This enzyme catalyses the following chemical reaction

2 nitric oxide + menaquinol ${\displaystyle \rightleftharpoons }$ nitrous oxide + menaquinone + H₂O

Nitric oxide reductase contains copper.

In 2015 the laboratory that had characterized the Bacillus azotoformans enzyme wrote, "The copper-A-dependent Nor from Bacillus azotoformans uses cytochrome c₅₅₁ as electron donor but lacks menaquinol activity, in contrast to our earlier report." ^[4]

References

1. Cramm R, Pohlmann A, Friedrich B (October 1999). "Purification and characterization of the single-component nitric oxide reductase from Ralstonia eutropha H16". FEBS Letters. 460 (1): 6–10. Bibcode:1999FEBSL.460....6C. doi:10.1016/s0014-5793(99)01315-0. PMID   10571051.
2. Strampraad MJ, Schröder I, de Vries S (February 2001). "A novel copper A containing menaquinol NO reductase from Bacillus azotoformans". Biochemistry. 40 (8): 2632–9. doi:10.1021/bi0020067. PMID   11327887.
3. Heering HA, de Vries S (October 2004). "NO reductase from Bacillus azotoformans is a bifunctional enzyme accepting electrons from menaquinol and a specific endogenous membrane-bound cytochrome c551". Biochemistry. 43 (42): 13487–95. doi:10.1021/bi0488101. PMID   15491156.
4. Al-Attar S, de Vries S (July 2015). "An electrogenic nitric oxide reductase". FEBS Letters. 589 (16): 2050–7. Bibcode:2015FEBSL.589.2050A. doi:10.1016/j.febslet.2015.06.033. PMID   26149211.

External links

• Nitric+oxide+reductase+(menaquinol) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)