Nova Southeastern University College of Dental Medicine

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Nova Southeastern University College of Dental Medicine
NSUcrestvector.png
Type Private university
Established1997
Dean Dr. Steven I. Kaltman (Interim)
Location,
FL
,
Website dental.nova.edu
Exterior of Dental School Building. NSU College of Dental Medicine.JPG
Exterior of Dental School Building.

The Nova Southeastern University College of Dental Medicine is the dental school of Nova Southeastern University. It is located in Fort Lauderdale, Florida, United States. When it opened in 1997, it was the first new dental school to open in the United States in 24 years. [1] It is the largest dental school in Florida. The school is accredited by the American Dental Association. [2]

Contents

Academics

In recent years, it has received more applications for admittance than any other dental school in the United States.[ citation needed ] There are approximately 3,500 applicants for the entering class size of 110. Entering first year students averaged in the 95th percentile nationally on the Dental Admission Test.[ citation needed ] It offers a four-year D.M.D. program, along with postdoctoral programs in: Advanced Education in General Dentistry (AEGD), Endodontics, Orthodontics, Pedodontics (Pediatric Dentistry), Periodontology, Prosthodontics, Oral and Maxillofacial Surgery (four years program), and Master of Science in Craniofacial Research. [1] [3]

Research

The NSU College of Dental Medicine is currently involved in Biomaterials development and research in Oral Biology. Some of the research being conducted:

Biomaterials Development

Microtensile fracture strength testing Profilometer fracture mode testing Fatigue, thermocycling and load testing Scanning electron microscope evaluation Leakage testing Hybrid layer evaluation Remineralization and demineralization studies ColorEye and Gloss analysis

Clinical Testing

Whitening kits Restorative materials Endodontic materials Periodontal therapies Prosthodontic devices Toothpaste Mouthwash Adhesives Disinfectants Analgesics Drugs Lasers Dental instruments and devices Toothbrushes (manual or power) Ortho appliances/devices Dental floss

Toothbrushing Dentifrice testing Abrasion testing Wear testing Clinical testing

Biocompatibility Testing Drugs and biomaterials In vitro cytotoxicity In vivo biocompatibility Histological assessment

Molecular Assays Protein/Gene activation PCR Gene silencing Gene isolation Molecular pathway elucidation

Pulp Biology

For over 50 years, from the 1950s until his death in 2002, oral pathologist Harold Stanley DDS, MS collected extracted teeth from across the world. Recently the histological archive was located at Nova Southeastern College of Dental Medicine. It is reportedly the largest and most compete histological archive in the world containing over 200,000 specimens and weighing more than 3 tons of teeth!

Dr. Stanley can be credited with establishing Oral Biology as the science we know today, prior to his efforts, the practice of dentistry and treatment planning had little regard for the biology of the oral tissues.

Dr. Stanley specialized in the soft tissue in the core of teeth called 'pulp'. The pulp is responsible for creating tooth dentin and for maintaining the vitality of the tooth throughout life. It is also responsible for the pain experienced if the tooth is diseased or damaged, and also for hot and cold sensitivity.

Dr. Stanley studied pulp death and regeneration. The photograph opposite shows the ability of the pulp cells to mineralize more tooth substance in response to injury. The purpose of the increased mineralization is to protect the pulp tissue from disease, injury and trauma. Dr. Stanley also showed that the bacterial invasion of teeth could destroy the cells and cause a loss of tooth vitality. The invasion of tooth dentinal tubules by bacteria can be seen in the photograph opposite. The bacteria is present in the mouth saliva. If bacteria reaches the pulp it can cause severe inflammation called 'pulpitis'. The pulpitis is normally painful and will require endodontic treatment. This involves the removal of the pulp and the cleaning and shaping of the root canals. The faculty and staff of Nova Southeastern are preparing the extensive histological archive of Dr. Stanley for on-line use. This will enable anyone to access his archive of teeth from anywhere in the world.

Stem Cells

Stem cells have the ability to continuously divide and differentiate (develop) into various other kinds of cells/tissues. All tissues originate from fetal stem cells. Recently adult stem cells have been identified with the ability to create new tissues. We investigate stem cells that are taken from donor adult tissues, we do not conduct any research using fetal stem cells. Tissue engineering is the creation of new replacement tissues Potential patients that could benefit from stem cell therapies (millions): Cardiovascular disease 58 Autoimmune diseases 30 Diabetes 16 Osteoporosis 10 Cancer 8.2 Alzheimer's disease 4.5 Parkinson's disease 1.5 Severe burns 0.3 Spinal cord injuries 0.25 Birth defects 0.15

Potential Therapies

Stem cells will be used as part of tissue engineering to create new tissues to replace diseased, missing and lost tissues: Disabled Accidents Cleft Palate Diabetes

Tissue Engineering

Tissue engineering is the creation of new tissues in the laboratory using stem cells, bioactive molecules and scaffolds. How we will use stem cells therapeutically: 1.Isolate stem cells from blood transfusion or cell culture (flow cytometer) 2.Proliferate the cells in culture using growth factors 3. Grow the cells around scaffold materials 4.Create organ culture conditions for a specific cell and tissue type 5.Transplant the new replacement tissues into patients

Elderly Oral Health

The incidence of diseases, and oral problems in the elderly requiring dental treatment is uncertain. In this study, the oral health of 265 South Florida nursing home residents aged between 45 and 98 years was assessed. The levels of tooth loss, oral hygiene scores, oral status, and the status of existing dentures are summarized.

See also

Related Research Articles

<span class="mw-page-title-main">Dentistry</span> Branch of medicine

Dentistry, also known as dental medicine and oral medicine, is the branch of medicine focused on the teeth, gums, and mouth. It consists of the study, diagnosis, prevention, management, and treatment of diseases, disorders, and conditions of the mouth, most commonly focused on dentition as well as the oral mucosa. Dentistry may also encompass other aspects of the craniofacial complex including the temporomandibular joint. The practitioner is called a dentist.

<span class="mw-page-title-main">Human tooth</span> Calcified whitish structure in humans mouths used to break down food

Human teeth function to mechanically break down items of food by cutting and crushing them in preparation for swallowing and digesting. As such, they are considered part of the human digestive system. Humans have four types of teeth: incisors, canines, premolars, and molars, which each have a specific function. The incisors cut the food, the canines tear the food and the molars and premolars crush the food. The roots of teeth are embedded in the maxilla or the mandible and are covered by gums. Teeth are made of multiple tissues of varying density and hardness.

<span class="mw-page-title-main">Dentist</span> Health care occupations caring for the mouth and teeth

A dentist, also known as a dental surgeon, is a health care professional who specializes in dentistry, the branch of medicine focused on the teeth, gums, and mouth. The dentist's supporting team aids in providing oral health services. The dental team includes dental assistants, dental hygienists, dental technicians, and sometimes dental therapists.

<span class="mw-page-title-main">Toothache</span> Medical condition of the teeth

Toothache, also known as dental pain or tooth pain, is pain in the teeth or their supporting structures, caused by dental diseases or pain referred to the teeth by non-dental diseases. When severe it may impact sleep, eating, and other daily activities.

<span class="mw-page-title-main">Pulp (tooth)</span> Part in the center of a tooth made up of living connective tissue and cells called odontoblasts

The pulp is the connective tissue, nerves, blood vessels, and odontoblasts that comprise the innermost layer of a tooth. The pulp's activity and signalling processes regulate its behaviour.

<span class="mw-page-title-main">Enamel organ</span> Aggregate of cells involved in tooth development

The enamel organ, also known as the dental organ, is a cellular aggregation seen in a developing tooth and it lies above the dental papilla. The enamel organ which is differentiated from the primitive oral epithelium lining the stomodeum. The enamel organ is responsible for the formation of enamel, initiation of dentine formation, establishment of the shape of a tooth's crown, and establishment of the dentoenamel junction.

Pulpitis is inflammation of dental pulp tissue. The pulp contains the blood vessels, the nerves, and connective tissue inside a tooth and provides the tooth's blood and nutrients. Pulpitis is mainly caused by bacterial infection which itself is a secondary development of caries. It manifests itself in the form of a toothache.

<span class="mw-page-title-main">Boston University Henry M. Goldman School of Dental Medicine</span>

The Boston University Henry M. Goldman School of Dental Medicine is the dental school of Boston University. Its curriculum is based on the Applied Professional Experience (APEX) Program, which gives students practical experience at a dental practice as part of clinical training. The School has about 800 students in predoctoral and postdoctoral programs.

<span class="mw-page-title-main">Veterinary dentistry</span> Branch of veterinary medicine

Veterinary dentistry is the field of dentistry applied to the care of animals. It is the art and science of prevention, diagnosis, and treatment of conditions, diseases, and disorders of the oral cavity, the maxillofacial region, and its associated structures as it relates to animals.

A pulp polyp, also known as chronic hyperplastic pulpitis, is a "productive" inflammation of dental pulp in which the development of granulation tissue is seen in response to persistent, low-grade mechanical irritation and bacterial invasion of the pulp.

<span class="mw-page-title-main">Root canal treatment</span> Dental treatment

Root canal treatment is a treatment sequence for the infected pulp of a tooth which is intended to result in the elimination of infection and the protection of the decontaminated tooth from future microbial invasion. Root canals, and their associated pulp chamber, are the physical hollows within a tooth that are naturally inhabited by nerve tissue, blood vessels and other cellular entities. Together, these items constitute the dental pulp.

Dental pertains to the teeth, including dentistry. Topics related to the dentistry, the human mouth and teeth include:

<span class="mw-page-title-main">Columbia University College of Dental Medicine</span>

The Columbia University College of Dental Medicine, often abbreviated CDM, is one of the twenty graduate and professional schools of Columbia University. It is located at 630 West 168th Street in Manhattan, New York City. According to American Dental Education Association, CDM is one of the most selective dental schools in the United States based on average DAT score, GPA, and acceptance rate. In 2014, 2,029 people applied for 80 positions in its entering class. The median undergraduate GPA and average DAT score for successful applicants in 2020 were 3.62 and 22.8, respectively.

<span class="mw-page-title-main">Pulpotomy</span>

Pulpotomy is a minimally invasive procedure performed in children on a primary tooth with extensive caries but without evidence of root pathology. The minimally invasive endodontic techniques of vital pulp therapy (VPT) are based on improved understanding of the capacity of pulp (nerve) tissues to heal and regenerate plus the availability of advanced endodontic materials. During the caries removal, this results in a carious or mechanical pulp exposure (bleeding) from the cavity. During pulpotomy, the inflamed/diseased pulp tissue is removed from the coronal pulp chamber of the tooth leaving healthy pulp tissue which is dressed with a long-term clinically successful medicament that maintains the survival of the pulp and promotes repair. There are various types of medicament placed above the vital pulp such as Buckley's Solution of formocresol, ferric sulfate, calcium hydroxide or mineral trioxide aggregate (MTA). MTA is a more recent material used for pulpotomies with a high rate of success, better than formocresol or ferric sulfate. It is also recommended to be the preferred pulpotomy agent in the future. After the coronal pulp chamber is filled, the tooth is restored with a filling material that seals the tooth from microleakage, such as a stainless steel crown which is the most effective long-term restoration. However, if there is sufficient remaining supporting tooth structure, other filling materials such as amalgam or composite resin can provide a functional alternative when the primary tooth has a life span of two years or less. The medium- to long-term treatment outcomes of pulpotomy in symptomatic permanent teeth with caries, especially in young people, indicate that pulpotomy can be a potential alternative to root canal therapy (RCT).

Pulp necrosis is a clinical diagnostic category indicating the death of cells and tissues in the pulp chamber of a tooth with or without bacterial invasion. It is often the result of many cases of dental trauma, caries and irreversible pulpitis.

Dental pulpal testing is a clinical and diagnostic aid used in dentistry to help establish the health of the dental pulp within the pulp chamber and root canals of a tooth. Such investigations are important in aiding dentists in devising a treatment plan for the tooth being tested.

<span class="mw-page-title-main">Pulp stone</span>

Pulp stones are nodular, calcified masses appearing in either or both the coronal and root portion of the pulp organ in teeth. Pulp stones are not painful unless they impinge on nerves.

<span class="mw-page-title-main">Regenerative endodontics</span> Dental specialty

Regenerative endodontic procedures is defined as biologically based procedures designed to replace damaged structures such as dentin, root structures, and cells of the pulp-dentin complex. This new treatment modality aims to promote normal function of the pulp. It has become an alternative to heal apical periodontitis. Regenerative endodontics is the extension of root canal therapy. Conventional root canal therapy cleans and fills the pulp chamber with biologically inert material after destruction of the pulp due to dental caries, congenital deformity or trauma. Regenerative endodontics instead seeks to replace live tissue in the pulp chamber. The ultimate goal of regenerative endodontic procedures is to regenerate the tissues and the normal function of the dentin-pulp complex.

<span class="mw-page-title-main">Pulp capping</span>

Pulp capping is a technique used in dental restorations to prevent the dental pulp from necrosis, after being exposed, or nearly exposed during a cavity preparation, from a traumatic injury, or by a deep cavity that reaches the center of the tooth causing the pulp to die. When dental caries is removed from a tooth, all or most of the infected and softened enamel and dentin are removed. This can lead to the pulp of the tooth either being exposed or nearly exposed which causes pulpitis (inflammation). Pulpitis, in turn, can become irreversible, leading to pain and pulp necrosis, and necessitating either root canal treatment or extraction. The ultimate goal of pulp capping or stepwise caries removal is to protect a healthy dental pulp and avoid the need for root canal therapy.

Platelet-rich fibrin (PRF) or leukocyte- and platelet-rich fibrin (L-PRF) is a derivative of PRP where autologous platelets and leukocytes are present in a complex fibrin matrix to accelerate the healing of soft and hard tissue and is used as a tissue-engineering scaffold for endodontics. PRF falls under FDA Product Code KST, labeling it as a blood draw/Hematology product classifying it as 510(k) exempt.

References

  1. 1 2 "First Look 2008" (PDF). Nova Southeastern University. Retrieved 16 August 2012.
  2. "Search DDS/DMD Programs". American Dental Association. Retrieved 9 July 2012.
  3. "MS in Dentistry". Nova Southeastern University College of Dental Medicine. 2012. Retrieved 15 August 2012.

26°4′44″N80°14′37″W / 26.07889°N 80.24361°W / 26.07889; -80.24361