Odd-Arne Olsen

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Odd-Arne Olsen
Odd Arne Olsen.jpg
Odd-Arne Olsen, Norwegian plant scientist
Born (1947-06-07) June 7, 1947 (age 78)
OccupationPlant scientist
EmployerNorwegian University of Life Sciences (Professor Emeritus)

Odd-Arne Olsen (born in 1947) is a Norwegian plant geneticist and molecular biologist. [1] [2]

Contents

He is recognized for his work on the development of cereal endosperm and research on foods with increased nutritional content [3] [4] and for leading Norway´s contribution to the sequencing of bread wheat chromosome 7B as part of the International Wheat Genome Sequencing Consortium where Olsen´s group at the Norwegian University of Life Sciences sequenced chromosome 7B. [5] [6]

This work has been described in international science media, such as Nature, The Atlantic, Phys.org and Science and Aftenposten as a key step toward understanding the wheat genome [7] [8] [9] and helping scientists develop better, more resilient and potentially less allergenic crop varieties, with possible long-term benefits for global food security. [10] [11] [12]

Olsen's team identified hundreds of wheat genes, including many linked to allergenic proteins, highlighting the potential for improved crop varieties. [7] The wheat genome sequencing project — including contributions from Olsen's group — was reported in Nature as a breakthrough in understanding the complex history and structure of bread wheat's genome. [13] Olsen is a professor emeritus at NMBU. [14]

Over a decades of research work Olsen´s work had impact shown through scholarly citations [15] [16] and public coverage.

Odd-Arne Olsen is educated in genetics from the University of Oslo (UiO) with a PhD in agricultural science from the Norwegian University of Life Sciences (NLH now NMBU). He worked in the Norwegian biotechnology program at UiO and NLH for a decade, and from 2001 at the companies Pioneer Hi-Bred DuPont and Monsanto in the USA, before returning to the Norwegian University of Life Sciences (NMBU). [17] [18] [19]

Books and Science Communication

He is the editor of Endosperm: Developmental and Molecular Biology, a comprehensive volume on cereal endosperm published by Springer.[ citation needed ] [20]

He is also the author of the book På genjakt etter mer og bedre mat (2024) [21] , which provides a comprehensive overview of plant biotechnology, including methods of genetic modification and gene editing, with examples drawn from industrial applications and research history in Norway and internationally. [22] [23] [24]

Olsen has participated in and contributed to public debates [25] and discussions on genetically modified food (GMO) and food security in Norway, including in leading newspapers such as Nationen, NRK and Aftenposten. [26] [27] [28] [29] [30]

Career and Research

Olsen´s research focused on the development of cereal endosperm. [31] [32] including the genetic regulation of aleurone cell development, the role of the cytoskeleton in endosperm morphogenesis. [33] Olsen and his collaborators demonstrated that ADP-glucose for starch synthesis in barley endosperm is produced in the cytosol rather than in the amyloplasts, a discovery that later formed the basis for patents. [34] [35] He also led studies that revealed the essential role of DEK1 in several developmental processes, including in the moss Physcomitrium patens. [36]

Olsen´s research group at NMBU contributed to the International Wheat Genome Sequencing Consortium by sequencing wheat chromosome 7B in collaboration with Graminor and several national and international partners. [37] Using the new reference genome, Olsen´s research group mapped seed-borne allergens and immunoresponsive proteins across bread wheat´s 21 chromosomes [38] and provided light on the origin of wheat [39] and characterized transcriptome of wheat endosperm. [40]

Olsen is also a co-inventor on several patents in plant biotechnology. [41] [42] In collaboration with Danisco A/S, Olsen is co-inventor on a patent for transgenic plants, including genetically modified potatoes that contain integrated nucleotide sequences enabling the production of specific sugar derivatives from sucrose within plant cells, a tool used in plant biotechnology research involving crop metabolic engineering. [43] [44]

He also collaborated with Pioneer Hi-Bred International on a gene expression system and was co-inventor of a patent for an aleurone-tissue-specific promoter (LTP2), which directs gene expression in the aleurone layer of developing cereal seeds such as maize, rice and barley and can be applied in research involving tissue-specific expression of genes in crop plants. [45] He now serves as Professor emeritus at NMBU.[ citation needed ] [46] [47]

References

  1. "Odd-Arne Olsen". scholar.google.com. Retrieved 2025-12-10.
  2. "Odd-Arne Olsen | Norwegian University of Life Sciences (NMBU), Ås | Department of Plant and Environmental Sciences (IPM)". ResearchGate. Archived from the original on 2022-11-07. Retrieved 2025-12-10.
  3. forskningsråd, Norges; Jakobsen, Siw Ellen (2001-06-01). "Genteknologi kan mette verden". www.forskning.no (in Norwegian Bokmål). Retrieved 2025-12-16.
  4. Røhme, Marianne (2011-02-25). "Identifisering av hvetegenomet vil revolusjonere planteavlen". Norsk Landbruk (in Norwegian). Retrieved 2025-12-16.
  5. International Wheat Genome Sequencing Consortium (2014-07-18). "A chromosome-based draft sequence of the hexaploid bread wheat (Triticum aestivum) genome". Science (New York, N.Y.). 345 (6194) 1251788. doi:10.1126/science.1251788. ISSN   1095-9203. PMID   25035500.
  6. The International Wheat Genome Sequencing Consortium; Appels, Rudi; Eversole, Kellye; Stein, Nils; Feuillet, Catherine; Keller, Beat; Rogers, Jane; Pozniak, Curtis J.; Choulet, Frédéric; Distelfeld, Assaf; Poland, Jesse; Ronen, Gil; Sharpe, Andrew G.; Barad, Omer; Baruch, Kobi (2018-08-17). "Shifting the limits in wheat research and breeding using a fully annotated reference genome". Science. 361 (6403) eaar7191. doi:10.1126/science.aar7191. PMID   30115783.
  7. 1 2 Yong, Ed (2018-08-16). "Scientists Finally Crack Wheat's Absurdly Complex Genome". The Atlantic. Retrieved 2025-12-11.
  8. Ledford, Heidi (2014-07-17). "Fiendish wheat genome reveals grain's history" . Nature. doi:10.1038/nature.2014.15577. ISSN   1476-4687.
  9. "Breakthrough will help increase food security with better, more robust wheat varieties". Phys.org. January 27, 2015.
  10. "Wheat's complex genome finally deciphered, offering hope for better harvests and nonallergenic varieties". www.science.org. Retrieved 2025-12-11.
  11. Eversole, Kellye; Feuillet, Catherine; Mayer, Klaus F. X.; Rogers, Jane (2014). "Slicing the wheat genome" . Science. 345 (6194): 285–287. Bibcode:2014Sci...345..285E. doi:10.1126/science.1257983 . Retrieved 2025-12-11.
  12. "Gener i hvete som forårsaker cøliaki er kartlagt. Det kan være ett skritt nærmere allergifri hvete". www.aftenposten.no (in Norwegian Bokmål). 2018-08-29. Retrieved 2025-12-11.
  13. "「曲者」のパンコムギゲノム、解読! | Nature ダイジェスト | Nature Portfolio". www.natureasia.com (in Japanese). Retrieved 2025-12-11.
  14. Aune, Ayla (2025-02-20). "SmåGENialt: Jakten på de gode genene". Bioteknologirådet (in Norwegian Bokmål). Retrieved 2025-12-11.
  15. "Odd-Arne Olsen". scholar.google.com. Retrieved 2025-12-17.
  16. Scopus https://www.scopus.com/authid/detail.uri?authorId=7102547804.{{cite web}}: Missing or empty |title= (help)
  17. "Folkeopplysning om plantebioteknologiens historie | NMBU". www.nmbu.no (in Norwegian Bokmål). Retrieved 2025-12-18.
  18. "Nasjonalbiblioteket". www.nb.no. Retrieved 2025-12-18.
  19. www.naturaoz.org http://web.archive.org/web/20240401053623/http://www.naturaoz.org/seminare_files/Odd-Arne_Olsen_Pozvanka.pdf. Archived from the original (PDF) on 2024-04-01. Retrieved 2025-12-18.{{cite web}}: Missing or empty |title= (help)
  20. Olsen, Odd-Arne, ed. (2007). "Endosperm" . Plant Cell Monographs. 8. doi:10.1007/978-3-540-71235-0. ISBN   978-3-540-71234-3. ISSN   1861-1370.
  21. "Nasjonalbiblioteket". www.nb.no. Retrieved 2025-12-11.
  22. Vitenparken (2025-01-16). Bokbad med professor Odd Arne Olsen: På genjakt etter mer og bedre mat . Retrieved 2025-12-11 via YouTube.
  23. "Bioteknologirådet (The Norwegian Biotechnology Advisory Board)" (PDF). January 2025. Retrieved December 14, 2025.
  24. "Folkeopplysning om plantebioteknologiens historie". www.nmbu.no (in Norwegian Bokmål). Retrieved 2025-12-11.
  25. "Debatter på tvers 15.2.: Genteknologi i en bærekraftig framtid? | NMBU". www.nmbu.no (in Norwegian Bokmål). Retrieved 2025-12-16.
  26. Olsen, Av Odd-Arne; Plantevitenskap, prof emeritus Institutt for; NMBU; Plantevitenskap, Åsmund Bjørnstad prof emeritus Institutt for; Graminor, NMBU og Muath Alsheikh Forskningssjef; Plantevitenskap, Institutt for; NMBU (2024-01-25). "Naturen «genredigerer» plantene våre hele tiden". Nationen (in Norwegian). Retrieved 2025-12-16.
  27. "Klimaforandring utfordrer norsk brødkornproduksjon". www.aftenposten.no (in Norwegian Bokmål). 2017-09-27. Retrieved 2025-12-16.
  28. biovitenskap, Universitetet for miljø-og; Solem, Trond (2008-06-03). "- Genmaten vil komme". www.forskning.no (in Norwegian Bokmål). Retrieved 2025-12-16.
  29. Hagen, Jon Georg (2008-09-04). "Forgiftet av GMO-mat". NRK (in Norwegian Bokmål). Retrieved 2025-12-16.
  30. "Fra Mayafolkets mais til GMO mais". Det Norske Videnskaps-Akademi (in Norwegian Bokmål). 2007-12-31. Retrieved 2025-12-16.
  31. Olsen, Odd-Arne (2004). "Nuclear endosperm development in cereals and Arabidopsis thaliana". The Plant Cell. 16 Suppl (Suppl): S214–227. Bibcode:2004PlanC..16S.214O. doi:10.1105/tpc.017111. ISSN   1040-4651. PMC   2643391 . PMID   15010513.
  32. Olsen, Odd-Arne (March 2020). "The Modular Control of Cereal Endosperm Development". Trends in Plant Science. 25 (3): 279–290. Bibcode:2020TPS....25..279O. doi:10.1016/j.tplants.2019.12.003. ISSN   1878-4372. PMID   31956036.
  33. Brown, R. C.; Lemmon, B. E.; Olsen, O. A. (September 1994). "Endosperm Development in Barley: Microtubule Involvement in the Morphogenetic Pathway". The Plant Cell. 6 (9): 1241–1252. doi:10.1105/tpc.6.9.1241. ISSN   1532-298X. PMC   160516 . PMID   12244271.
  34. Thorbjørnsen, T.; Villand, P.; Kleczkowski, L. A.; Olsen, O. A. (1996-01-01). "A single gene encodes two different transcripts for the ADP-glucose pyrophosphorylase small subunit from barley (Hordeum vulgare)". The Biochemical Journal. 313 ( Pt 1) (Pt 1): 149–154. doi:10.1042/bj3130149. ISSN   0264-6021. PMC   1216875 . PMID   8546676.
  35. Doan, D. N.; Rudi, H.; Olsen, O. A. (September 1999). "The Allosterically Unregulated Isoform of ADP-Glucose Pyrophosphorylase from Barley Endosperm Is the Most Likely Source of ADP-Glucose Incorporated into Endosperm Starch". Plant Physiology. 121 (3): 965–975. Bibcode:1999PlanP.121..965D. doi:10.1104/pp.121.3.965. ISSN   1532-2548. PMC   59461 . PMID   10557246.
  36. Demko, Viktor; Belova, Tatiana; Messerer, Maxim; Hvidsten, Torgeir R.; Perroud, Pierre-François; Ako, Ako Eugene; Johansen, Wenche; Mayer, Klaus F. X.; Olsen, Odd-Arne; Lang, Daniel (2024-03-04). "Regulation of developmental gatekeeping and cell fate transition by the calpain protease DEK1 in Physcomitrium patens". Communications Biology. 7 (1): 261. doi:10.1038/s42003-024-05933-z. ISSN   2399-3642. PMC   10912778 . PMID   38438476.
  37. Kjelby, Daniel (2016-01-25). "Forskningsprosjekt for over 16 millioner til Graminor". Graminor (in Norwegian Bokmål). Retrieved 2025-12-11.
  38. Juhász, Angéla; Belova, Tatiana; Florides, Chris G.; Maulis, Csaba; Fischer, Iris; Gell, Gyöngyvér; Birinyi, Zsófia; Ong, Jamie; Keeble-Gagnère, Gabriel; Maharajan, Amudha; Ma, Wujun; Gibson, Peter; Jia, Jizeng; Lang, Daniel; Mayer, Klaus F. X. (2018-08-03). "Genome mapping of seed-borne allergens and immunoresponsive proteins in wheat". Science Advances. 4 (8) eaar8602. Bibcode:2018SciA....4.8602J. doi:10.1126/sciadv.aar8602. ISSN   2375-2548. PMC   6097586 . PMID   30128352.
  39. Marcussen, Thomas; Sandve, Simen R.; Heier, Lise; Spannagl, Manuel; Pfeifer, Matthias; Jakobsen, Kjetill S.; Wulff, Brande B. H.; Steuernagel, Burkhard; Mayer, Klaus F. X.; Olsen, Odd-Arne; Rogers, Jane; Doležel, Jaroslav; Pozniak, Curtis; Eversole, Kellye; Feuillet, Catherine (2014-07-18). "Ancient hybridizations among the ancestral genomes of bread wheat". Science. 345 (6194) 1250092. doi:10.1126/science.1250092. ISSN   0036-8075. PMID   25035499.
  40. Pfeifer, Matthias; Kugler, Karl G.; Sandve, Simen R.; Zhan, Bujie; Rudi, Heidi; Hvidsten, Torgeir R.; International Wheat Genome Sequencing Consortium; Mayer, Klaus F. X.; Olsen, Odd-Arne (2014-07-18). "Genome interplay in the grain transcriptome of hexaploid bread wheat". Science. 345 (6194) 1250091. Bibcode:2014Sci...34550091P. doi:10.1126/science.1250091. ISSN   0036-8075. PMID   25035498.
  41. US5525716A,Olsen, Odd-Arne&Kalla, Roger,"LPT2 promoter having aleurone-tissue-specific activity",issued 1996-06-11
  42. US6031152A,Olsen, Odd-Arne; Kalla, Roger& Linnestad, Casper,"Promoter from a lipid transfer protein gene",issued 2000-02-29
  43. US5977437A,Villand, Per; Kleczkowski, Leszek& Olsen, Odd-Arneet al.,"Transgenic plants or algae expressing an AGP enzyme coupled to a transit peptide",issued 1999-11-02
  44. Olsen, Av Odd-Arne; Plantevitenskap, prof emeritus Institutt for; NMBU; Plantevitenskap, Åsmund Bjørnstad prof emeritus Institutt for; Graminor, NMBU og Muath Alsheikh Forskningssjef; Plantevitenskap, Institutt for; NMBU (2024-01-25). "Naturen «genredigerer» plantene våre hele tiden". Nationen (in Norwegian). Retrieved 2025-12-11.
  45. US5525716A,Olsen, Odd-Arne&Kalla, Roger,"LPT2 promoter having aleurone-tissue-specific activity",issued 1996-06-11
  46. Aune, Ayla (2025-02-20). "SmåGENialt: Jakten på de gode genene". Bioteknologirådet (in Norwegian Bokmål). Retrieved 2025-12-12.
  47. "Odd-Arne Olsen". scholar.google.com. Retrieved 2025-12-12.