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A genetically modified potato is a potato that has had its genes modified, using genetic engineering. Goals of modification include introducing pest resistance, tweaking the amounts of certain chemicals produced by the plant, and to prevent browning or bruising of the tubers. Varieties modified to produce large amounts of starches may be approved for industrial use only, not for food.
The genetically modified Innate potato was approved by the United States Department of Agriculture in 2014 [1] and the US FDA in 2015. [2] [3] [4] The cultivar was developed by J. R. Simplot Company. It is designed to resist blackspot bruising, browning and to contain less of the amino acid asparagine that turns into acrylamide during the frying of potatoes. Acrylamide is a probable human carcinogen, so reduced levels of it in fried potato foods is desirable. [5] [6] Though, browning does not affect the quality of the potato, it is simply that consumers tend to not want to purchase "damaged" or possibly spoiled [7] goods. The 'Innate' name comes from the fact that this variety does not contain any genetic material from other species (the genes used are "innate" to potatoes) and uses RNA interference to switch off genes. Simplot hopes that not including genes from other species will assuage consumer fears about biotechnology. [5]
The "Innate" potato is not a single cultivar; rather, it is a group of potato varieties that have had the same genetic alterations applied using the same process. Five different potato varieties have been transformed, creating "innate" versions of the varieties, with all of the original traits, plus the engineered ones. Ranger Russet, Russet Burbank, and Atlantic potatoes have all been transformed by Simplot, as well as two proprietary varieties. Modifications of each variety involved two transformations, one for each of the two new traits. Thus there was a total of ten transformation events in developing the different Innate varieties. [8]
McDonald's is a major consumer of potatoes in the US. The Food and Water Watch has petitioned the company to reject the newly marketed Innate potatoes. [9] McDonald's has announced that they have ruled out using Innate. [10]
In 1995, Monsanto introduced the NewLeaf variety of potato which was their first genetically modified crop. It was designed to resist attack from the Colorado potato beetle due to the insertion of Bt toxin producing genes from the bacterium Bacillus thuringiensis . The insect-resistant potatoes found only a small market, and Monsanto discontinued the sale of seed in 2001. [11]
'Amflora' (also known as EH92-527-1) was a cultivar developed by BASF Plant Science for production of pure amylopectin starch for processing into waxy potato starch. [12] It was approved for industrial applications in the European Union market on 2 March 2010 by the European Commission, [13] but was withdrawn from the EU market in January 2012 due to a lack of acceptance from farmers and consumers. [14]
A modified Désirée potato was developed in the 1990s by biochemist [15] John Gatehouse at Cambridge Agricultural Genetics (later renamed Axis Genetics) and had gone through two years of field trials at Rothamsted Experimental Station. [16] The potatoes were modified to express the Galanthus nivalis agglutinin (GNA) gene from the Galanthus (snowdrop) plant, which caused them to produce GNA lectin protein that is toxic to some insects. [17] [18] This variety of potatoes is the one which was involved in the Pusztai affair.
Other similar research - into transgenic Désirées, with antifeedant chemicals transferred from other plants, a few years before, with a researcher from Axis - was also done by a team including Gatehouse and his wife Angharad. At this time the Gatehouses were both at the University of Durham. [19]
In 2014, a team of British scientists published a paper about three-year field trial showing that another genetically modified version of the Désirée cultivar can resist infection after exposure to late blight, one of the most serious diseases of potatoes. They developed this potato for blight resistance by inserting a gene (Rpi-vnt1.1), into the DNA of Désirée potatoes. This gene, which conferred the resistance to blight, was isolated from a wild relative of potatoes, Solanum venturii , which is a native of South America. [20] [21]
In 2017 scientists in Bangladesh developed their own variety of blight resistant GM potato. [22]
Genetically modified maize (corn) is a genetically modified crop. Specific maize strains have been genetically engineered to express agriculturally-desirable traits, including resistance to pests and to herbicides. Maize strains with both traits are now in use in multiple countries. GM maize has also caused controversy with respect to possible health effects, impact on other insects and impact on other plants via gene flow. One strain, called Starlink, was approved only for animal feed in the US but was found in food, leading to a series of recalls starting in 2000.
The potato is a starchy root vegetable native to the Americas that is consumed as a staple food in many parts of the world. Potatoes are tubers of the plant Solanum tuberosum, a perennial in the nightshade family Solanaceae.
Agricultural biotechnology, also known as agritech, is an area of agricultural science involving the use of scientific tools and techniques, including genetic engineering, molecular markers, molecular diagnostics, vaccines, and tissue culture, to modify living organisms: plants, animals, and microorganisms. Crop biotechnology is one aspect of agricultural biotechnology which has been greatly developed upon in recent times. Desired trait are exported from a particular species of Crop to an entirely different species. These transgene crops possess desirable characteristics in terms of flavor, color of flowers, growth rate, size of harvested products and resistance to diseases and pests.
Genetically modified foods, also known as genetically engineered foods, or bioengineered foods are foods produced from organisms that have had changes introduced into their DNA using various methods of genetic engineering. Genetic engineering techniques allow for the introduction of new traits as well as greater control over traits when compared to previous methods, such as selective breeding and mutation breeding.
Flavr Savr, a genetically modified tomato, was the first commercially grown genetically engineered food to be granted a license for human consumption. It was developed by the Californian company Calgene in the 1980s. The tomato has an improved shelf-life, increased fungal resistance and a slightly increased viscosity compared to its non-modified counterpart. It was meant to be harvested ripe for increased flavor for long-distance shipping. The Flavr Savr contains two genes added by Calgene; a reversed antisense polygalacturonase gene which inhibits the production of the aforementioned rotting enzyme and a gene responsible for the creation of APH(3')II, which confers resistance to certain aminoglycoside antibiotics including kanamycin and neomycin. On May 18, 1994, the FDA completed its evaluation of the Flavr Savr tomato and the use of APH(3')II, concluding that the tomato "is as safe as tomatoes bred by conventional means" and "that the use of aminoglycoside 3'-phosphotransferase II is safe for use as a processing aid in the development of new varieties of tomato, rapeseed oil, and cotton intended for food use." It was first sold in 1994, and was only available for a few years before production ceased in 1997. Calgene made history, but mounting costs prevented the company from becoming profitable, and it was eventually acquired by Monsanto Company.
The J. R. Simplot Company is an agribusiness company headquartered in Boise, Idaho.
Árpád János Pusztai was a Hungarian-born British biochemist and nutritionist who spent 36 years at the Rowett Research Institute in Aberdeen, Scotland. He was a world expert on plant lectins, authoring 270 papers and three books on the subject.
Genetically modified crops are plants used in agriculture, the DNA of which has been modified using genetic engineering methods. Plant genomes can be engineered by physical methods or by use of Agrobacterium for the delivery of sequences hosted in T-DNA binary vectors. In most cases, the aim is to introduce a new trait to the plant which does not occur naturally in the species. Examples in food crops include resistance to certain pests, diseases, environmental conditions, reduction of spoilage, resistance to chemical treatments, or improving the nutrient profile of the crop. Examples in non-food crops include production of pharmaceutical agents, biofuels, and other industrially useful goods, as well as for bioremediation.
Galanthus nivalis, the snowdrop or common snowdrop, is the best-known and most widespread of the 20 species in its genus, Galanthus. Snowdrops are among the first bulbs to bloom in spring and can form impressive carpets of white in areas where they are native or have been naturalised. They should not be confused with the snowflakes, in the genera Leucojum and Acis.
Genetically modified food controversies are disputes over the use of foods and other goods derived from genetically modified crops instead of conventional crops, and other uses of genetic engineering in food production. The disputes involve consumers, farmers, biotechnology companies, governmental regulators, non-governmental organizations, and scientists. The key areas of controversy related to genetically modified food are whether such food should be labeled, the role of government regulators, the objectivity of scientific research and publication, the effect of genetically modified crops on health and the environment, the effect on pesticide resistance, the impact of such crops for farmers, and the role of the crops in feeding the world population. In addition, products derived from GMO organisms play a role in the production of ethanol fuels and pharmaceuticals.
The United States is the largest grower of commercial crops that have been genetically engineered in the world, but not without domestic and international opposition.
Genetically modified wheat is wheat that has been genetically engineered by the direct manipulation of its genome using biotechnology. As of 2020, no GM wheat is grown commercially, although many field tests have been conducted, with one wheat variety, Bioceres HB4 Wheat, obtaining regulatory approval from the Argentinean government.
Genetically modified rice are rice strains that have been genetically modified. Rice plants have been modified to increase micronutrients such as vitamin A, accelerate photosynthesis, tolerate herbicides, resist pests, increase grain size, generate nutrients, flavors or produce human proteins.
A genetically modified soybean is a soybean that has had DNA introduced into it using genetic engineering techniques. In 1996, the first genetically modified soybean was introduced to the U.S. by Monsanto. In 2014, 90.7 million hectares of GM soybeans were planted worldwide, this is almost 82% of the total soybeans cultivation area.
BASF Plant Science is a subsidiary of BASF in which all plant biotechnology activities are consolidated. The company was founded in 1998 and employs approximately 700 people at 6 different locations worldwide. The headquarters of BASF Plant Science is located in Research Triangle Park and has research sites in the US, Canada, and Europe. The company mainly develops genetically modified seeds at these locations.
The Pusztai affair is a controversy that began in 1998. The protein scientist Árpád Pusztai went public with the initial results of unpublished research he was conducting at the Rowett Institute in Aberdeen, Scotland, investigating the possible effects of genetically modified potatoes upon rats. Pusztai claimed that the genetically modified potatoes had stunted growth and repressed the rats' immune systems while thickening their gut mucosa. Initially supported by the Rowett Institute, his comments on a British television programme caused a storm of controversy, and the Rowett Institute withdrew its support. Pusztai was suspended and misconduct procedures were used to seize his data and ban him from speaking publicly. The institute did not renew his annual contract and Pusztai was criticized by the Royal Society and some other scientists for making an announcement before his experiment was complete or peer-reviewed and for the experiment's design, methodology and analysis. Some of the data from the study was eventually published in The Lancet in 1999 after five out of six peer reviewers approved of the study – triggering further controversy.
Genetic engineering in the European Union has varying degrees of regulation.
Genetic engineering in Hawaii is a hotly contested political topic. The Hawaiian islands counties of Kauai, Hawaii and Maui passed or considered laws restricting the practice within their borders due to concerns about the health, the environment and impacts on conventional and organic agriculture.
Lenape (B5141-6) is a potato cultivar first released in 1967 and named after the Lenape Native American tribe, which had to be pulled from the market in 1970 after findings of its high glycoalkaloid content. It was bred by Wilford Mills of Pennsylvania State University in collaboration with the Wise Potato Chip Company. The Lenape potato was produced by crossing Delta Gold with a wild Peruvian potato known for its resistance to insects. It was selected for its high specific gravity and low sugar content which made it ideal for producing potato chips but it was also immune to potato virus A and resistant to common strains of late blight. It is of medium-late maturity and produces round, white tubers with shallow eyes.
Genetic engineering in North America is any genetic engineering activities in North America