Company type | Private |
---|---|
Industry | |
Founded | 2014 |
Founder |
|
Headquarters | , United States |
Key people | Jon Brennan-Badal (CEO) |
Products |
|
Number of employees | 328 (2023) |
Website | opentrons |
Opentrons Labworks, Inc. (or Opentrons) is a biotechnology company that manufactures liquid handling robots that use open-source software, which at one point used open-source hardware but no longer does.[ citation needed ] Their robots can be used by scientists to manipulate small volumes of liquids for the purpose of undertaking biochemical or chemical reactions. Currently, they offer the OT-2 and Flex robots. These robots are used primarily by researchers and scientists interested in DIY biology, but they are increasingly being used by other biologists. [1]
Current:
Discontinued:
The company originated from Genspace, a community biology laboratory in Brooklyn, New York. Will Canine, a biohacker and former Occupy Wall Street organizer, partnered with Nicholas Wagner and Chiu Chau as his eventual co-founders who he found from a DIY-bio listserve. [14]
In 2014, the startup officially launched with financial backing from HAXLR8TR, a hardware accelerator in Shenzhen, China. In late 2014, they launch a Kickstarter campaign. [10] [14] They show their machine inserting DNA inside E. coli after their campaign successfully gets funded. [15] Jonathan Brennan-Badal, who was VP of strategy at ComiXology and a board member of Genspace, joined Opentrons in 2014 and is the current CEO. [16]
In 2016, Opentrons was part of Y Combinator's Winter cohort of startups. [17]
Opentrons robots have had a variety of uses in the scientific and DIY community. Scientists at UCSD modified an existing OT-1 robot to automate adding in reagents and imaging their cell signaling experiments. [1] Scientists at Carnegie Mellon University used the OT-2, Opentrons Python API, and OpenAI's GPT-4 to autonomously design, plan, and perform experiments. [18]
During the COVID-19 pandemic, Opentrons helped set up the Pandemic Response Lab (PRL), a sequencing facility located in Queens, New York. [19] Opentrons' robots at the PRL helped speed up turnaround time for COVID-19 testing, going from 7 to 14 days to 12 hours, and reducing costs from $2,000 to under $28. [20] Institutions that made use of Opentrons' robots for COVID-19 testing include: Mayo Clinic, Harvard, Stanford, Caltech, MIT, and BioNTech. [14]
As a company, Opentrons has a number of subsidiaries. [21]
A pipette is a type of laboratory tool commonly used in chemistry and biology to transport a measured volume of liquid, often as a media dispenser. Pipettes come in several designs for various purposes with differing levels of accuracy and precision, from single piece glass pipettes to more complex adjustable or electronic pipettes. Many pipette types work by creating a partial vacuum above the liquid-holding chamber and selectively releasing this vacuum to draw up and dispense liquid. Measurement accuracy varies greatly depending on the instrument.
Laboratory robotics is the act of using robots in biology, chemistry or engineering labs. For example, pharmaceutical companies employ robots to move biological or chemical samples around to synthesize novel chemical entities or to test pharmaceutical value of existing chemical matter. Advanced laboratory robotics can be used to completely automate the process of science, as in the Robot Scientist project.
Open-source hardware consists of physical artifacts of technology designed and offered by the open-design movement. Both free and open-source software (FOSS) and open-source hardware are created by this open-source culture movement and apply a like concept to a variety of components. It is sometimes, thus, referred to as FOSH. The term usually means that information about the hardware is easily discerned so that others can make it – coupling it closely to the maker movement. Hardware design, in addition to the software that drives the hardware, are all released under free/libre terms. The original sharer gains feedback and potentially improvements on the design from the FOSH community. There is now significant evidence that such sharing can drive a high return on investment for the scientific community.
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Do-it-yourself biology is a biotechnological social movement in which individuals, communities, and small organizations study biology and life science using the same methods as traditional research institutions. DIY biology is primarily undertaken by individuals with limited research training from academia or corporations, who then mentor and oversee other DIY biologists with little or no formal training. This may be done as a hobby, as a not-for-profit endeavor for community learning and open-science innovation, or for profit, to start a business.
The maker culture is a contemporary subculture representing a technology-based extension of DIY culture that intersects with hardware-oriented parts of hacker culture and revels in the creation of new devices as well as tinkering with existing ones. The maker culture in general supports open-source hardware. Typical interests enjoyed by the maker culture include engineering-oriented pursuits such as electronics, robotics, 3-D printing, and the use of computer numeric control tools, as well as more traditional activities such as metalworking, woodworking, and, mainly, its predecessor, traditional arts and crafts.
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Jonathan "Joe" Betts-LaCroix is an American scientist and entrepreneur known for his discoveries in biophysics and for creating the world's smallest personal computer. He is working to optimize medical research priorities in the U.S.
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Genspace is a non-profit organization and a community biology laboratory located in Brooklyn, New York. Stemming from the hacking, biohacking, and DIYbio movements, Genspace has focused on supporting citizen science and public access to biotechnology. Genspace opened the first community biology lab in 2010 and a Biosafety Level One laboratory in December of that year. Since its opening, Genspace has supported projects, events, courses, art, and general community resources concerning biology, biotechnology, synthetic biology, genetic engineering, citizen science, open source software, open source hardware, and more.
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Ellen D. Jorgensen is a New York-based molecular biologist and serial entrepreneur. In addition to her long career in the biotechnology industry she is also credited with playing a leading role in promoting the do-it-yourself biology movement where she has worked to increase scientific literacy in the general population, particularly in the fields of molecular and synthetic biology. She is a co-founder of both non-profit and for-profit biotechnology-based companies. In 2017, Ellen Jorgensen was named one of the Most Creative Leaders in Business by Fast Company. Her current focus is on combating climate change through her role as Vice President of Biotechnology at CarbonBridge, a biotech startup that uses bacteria to remove environmental methane and create liquid fuel.
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