Primary interventricular foramen | |
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Details | |
Location | Embryonic heart |
Identifiers | |
Latin | foramen interventriculare primarium |
TE | E5.11.1.3.2.0.14 |
Anatomical terminology |
In human embryology, the primary interventricular foramen is a temporary opening between the developing ventricles of the heart. The ventricles arise as a single cavity that is divided by the developing interventricular septum. Before the septum closes completely, the remaining opening between the two ventricles is termed the interventricular foramen.
In some individuals, the foramen fails to close, leading to an interventricular septal defect known as a patent interventricular foramen. [1]
Coronary circulation is the circulation of blood in the blood vessels that supply the heart muscle (myocardium). Coronary arteries supply oxygenated blood to the heart muscle, and cardiac veins drain away the blood once it has been deoxygenated. Because the rest of the body, and most especially the brain, needs a steady supply of oxygenated blood that is free of all but the slightest interruptions, the heart is required to function continuously. Therefore its circulation is of major importance not only to its own tissues but to the entire body and even the level of consciousness of the brain from moment to moment. Interruptions of coronary circulation quickly cause heart attacks, in which the heart muscle is damaged by oxygen starvation. Such interruptions are usually caused by ischemic heart disease and sometimes by embolism from other causes like obstruction in blood flow through vessels.
The ventricular system is a set of four interconnected cavities (ventricles) in the brain, where the cerebrospinal fluid (CSF) is produced. Within each ventricle is a region of choroid plexus, a network of ependymal cells involved in the production of CSF. The ventricular system is continuous with the central canal of the spinal cord, allowing for the flow of CSF to circulate. All of the ventricular system and the central canal of the spinal cord are lined with ependyma, a specialised form of epithelium.
In anatomy, a foramen is any opening. Foramina inside the body of humans and other animals typically allow muscles, nerves, arteries, veins, or other structures to connect one part of the body with another.
The pulmonary circulation is the portion of the circulatory system which carries deoxygenated blood away from the right ventricle, to the lungs, and returns oxygenated blood to the left atrium and ventricle of the heart. The term pulmonary circulation is readily paired and contrasted with the systemic circulation. The vessels of the pulmonary circulation are the pulmonary arteries and the pulmonary veins.
Atrial septal defect (ASD) is a congenital heart defect in which blood flows between the atria of the heart. Some flow is a normal condition both pre-birth and immediately post-birth via the foramen ovale; however, when this does not naturally close after birth it is referred to as a patent (open) foramen ovale (PFO).
The atrium is the upper chamber through which blood enters the ventricles of the heart. There are two atria in the human heart – the left atrium receives blood from the pulmonary (lung) circulation, and the right atrium receives blood from the venae cavae. The atria receive blood while relaxed (diastole), then contract (systole) to move blood to the ventricles. All animals with a closed circulatory system have at least one atrium. Humans have two atria.
The lateral ventricles are the two largest cavities of the ventricular system of the human brain and contain cerebrospinal fluid (CSF). Each cerebral hemisphere contains a lateral ventricle, known as the left or right ventricle, respectively.
In the brain, the interventricular foramina are channels that connect the paired lateral ventricles with the third ventricle at the midline of the brain. As channels, they allow cerebrospinal fluid (CSF) produced in the lateral ventricles to reach the third ventricle and then the rest of the brain's ventricular system. The walls of the interventricular foramina also contain choroid plexus, a specialized CSF-producing structure, that is continuous with that of the lateral and third ventricles above and below it.
In the fetal heart, the foramen ovale, also foramen Botalli, or the ostium secundum of Born, allows blood to enter the left atrium from the right atrium. It is one of two fetal cardiac shunts, the other being the ductus arteriosus. Another similar adaptation in the fetus is the ductus venosus. In most individuals, the foramen ovale closes at birth. It later forms the fossa ovalis.
The interventricular septum is the stout wall separating the ventricles, the lower chambers of the heart, from one another.
The interatrial septum is the wall of tissue that separates the right and left atria of the heart.
The primitive ventricle or embryonic ventricle of the developing heart, together with the bulbus cordis that lies in front of it, gives rise to the left and right ventricles. The primitive ventricle provides the trabeculated parts of the walls, and the bulbus cordis the smooth parts.
The hypothalamic sulcus is a groove in the lateral wall of the third ventricle, marking the boundary between the thalamus and hypothalamus. The upper and lower portions of the lateral wall of the third ventricle correspond to the alar lamina and basal lamina, respectively, of the lateral wall of the fore-brain vesicle and are separated from each other by a furrow, the hypothalamic sulcus, which extends from the interventricular foramen to the cerebral aqueduct.
The foramen secundum, or ostium secundum is a foramen in the septum primum, a precursor to the interatrial septum of the human heart.
In the developing heart, the atria are initially open to each other, with the opening known as the primary interatrial foramen or ostium primum. The foramen lies beneath the edge of septum primum and the endocardial cushions. It progressively decreases in size as the septum grows downwards, and disappears with the formation of the atrial septum.
The aorticopulmonary septum is developmentally formed from neural crest, specifically the cardiac neural crest, and actively separates the aorta and pulmonary arteries and fuses with the interventricular septum within the heart during heart development.
Ventricular inversion, is a condition in which the anatomic right ventricle of the heart is on the left side of the interventricular septum and the anatomic left ventricle is on the right.
The heart is the first functional organ in a vertebrate embryo. There are 5 stages to heart development.
Heart development refers to the prenatal development of the human heart. This begins with the formation of two endocardial tubes which merge to form the tubular heart, also called the primitive heart tube, that loops and septates into the four chambers and paired arterial trunks that form the adult heart. The heart is the first functional organ in vertebrate embryos, and in the human, beats spontaneously by week 4 of development.
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