Quintuple bond

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The structure of [CrC6H3-2,6-(C6H3-2,6-(CHMe2)2)2]2 Ar2Cr2PP.svg
The structure of [CrC6H3-2,6-(C6H3-2,6-(CHMe2)2)2]2

A quintuple bond in chemistry is an unusual type of chemical bond, first reported in 2005 for a dichromium compound. Single bonds, double bonds, and triple bonds are commonplace in chemistry. Quadruple bonds are rarer but are currently known only among the transition metals, especially for Cr, Mo, W, and Re, e.g. [Mo2Cl8]4− and [Re2Cl8]2−. In a quintuple bond, ten electrons participate in bonding between the two metal centers, allocated as σ2π4δ4.


In some cases of high-order bonds between metal atoms, the metal-metal bonding is facilitated by ligands that link the two metal centers and reduce the interatomic distance. By contrast, the chromium dimer with quintuple bonding is stabilized by a bulky terphenyl (2,6-[(2,6-diisopropyl)phenyl]phenyl) ligands. The species is stable up to 200 °C. [1] [2] The chromium–chromium quintuple bond has been analyzed with multireference ab initio and DFT methods, [3] which were also used to elucidate the role of the terphenyl ligand, in which the flanking aryls were shown to interact very weakly with the chromium atoms, causing only a small weakening of the quintuple bond. [4] A 2007 theoretical study identified two global minima for quintuple bonded RMMR compounds: a trans-bent molecular geometry and surprisingly another trans-bent geometry with the R substituent in a bridging position. [5]

In 2005, a quintuple bond was postulated to exist in the hypothetical uranium molecule U2 based on computational chemistry. [6] [7] Diuranium compounds are rare, but do exist; for example, the U

In 2007 the shortest-ever metal–metal bond (180.28 pm) was reported to exist also in a compound containing a quintuple chromium-chromium bond with diazadiene bridging ligands. [8] Other metal–metal quintuple bond containing complexes that have been reported include quintuply bonded dichromium with [6-(2,4,6-triisopropylphenyl)pyridin-2-yl](2,4,6-trimethylphenyl)amine bridging ligands [9] and a dichromium complex with amidinate bridging ligands. [10]

Synthesis of quintuple bonds is usually achieved through reduction of a dimetal species using potassium graphite. This adds valence electrons to the metal centers, giving them the needed number of electrons to participate in quintuple bonding. Below is a figure of a typical quintuple bond synthesis.

Cr-Cr quintuple bond synthesis Quintuple bond synthesis.png
Cr–Cr quintuple bond synthesis

Dimolybdenum quintuple bonds

In 2009 a dimolybdenum compound with a quintuple bond and two diamido bridging ligands was reported with a Mo–Mo bond length of 202 pm. [11] The compound was synthesised starting from potassium octachlorodimolybdate (which already contains a Mo2 quadruple bond) and a lithium amidinate, followed by reduction with potassium graphite:

dimolybdenum quintuple bond synthesis Mo quintuple bond synthesis3.png
dimolybdenum quintuple bond synthesis


As stated above metal-metal quintuple bonds have a σ2π4δ4 configuration. Among the five bonds present between the metal centers, one is a sigma bond, two are pi bonds, and two are delta bonds. The σ-bond is the result of mixing between the dz2 orbital on each metal center. The first π-bond comes from mixing of the dyz orbitals from each metal while the other π-bond comes from the dxz orbitals on each metal mixing. Finally the δ-bonds come from mixing of the dxy orbitals as well as mixing between the dx2y2 orbitals from each metal.

Molecular orbital calculations have elucidated the relative energies of the orbitals created by these bonding interactions. As shown in the figure below, the lowest energy orbitals are the π bonding orbitals followed by the σ bonding orbital. The next highest are the δ bonding orbitals which represent the HOMO. Because the 10 valence electrons of the metals are used to fill these first 5 orbitals, the next highest orbital becomes the LUMO which is the δ* antibonding orbital. Though the π and δ orbitals are represented as being degenerate, they in fact are not. This is because the model shown here is a simplification and that hybridization of s, p, and d orbitals is believed to take place, causing a change in the orbital energy levels.[ citation needed ]

MO diagram of a metal-metal quintuple bond Quintuple bond MO diagram.png
MO diagram of a metal–metal quintuple bond

Ligand role in metal–metal quintuple bond length

Quintuple bond lengths are heavily dependent on the ligands bound to the metal centers. Nearly all complexes containing a metal–metal quintuple bond have bidentate bridging ligands, and even those that do not, such as the terphenyl complex mentioned earlier, have some bridging characteristic to it through metal–ipso-carbon interactions.

The bidentate ligand can act as a sort of tweezer in that in order for chelation to occur the metal atoms must move closer together, thereby shortening the quintuple bond length. The two ways in which to obtain shorter metal–metal distances is to either reduce the distance between the chelating atoms in the ligand by changing the structure, or by using steric effects to force a conformational change in the ligand that bends the molecule in a way that forces the chelating atoms closer together. An example of the latter is shown below:

Steric effects on a bidentate ligand Bidentate ligand steric effects.png
Steric effects on a bidentate ligand

The above example shows the ligand used in the dimolybdenum complex shown earlier. When the carbon between the two nitrogens in the ligand has a hydrogen bound to it, the steric repulsion is small. However, when the hydrogen is replaced with a much more bulky phenyl ring the steric repulsion increases dramatically and the ligand "bows" which causes a change in the orientation of the lone pairs of electrons on the nitrogen atoms. These lone pairs are what is responsible for forming bonds with the metal centers so forcing them to move closer together also forces the metal centers to be positioned closer together. Thus, decreasing the length of the quintuple bond. In the case where this ligand is bound to quintuply bonded dimolybdenum the quintuple bond length goes from 201.87 pm to 201.57 pm when the hydrogen in replaced with a phenyl group. Similar results have also been demonstrated in dichromium quintuple bond complexes as well. [12]

Efforts continue to prepare shorter quintuple bonds. [13] [14]

Quintuple-bonded dichromium complexes appear to act like magnesium to produce Grignard reagents. [15]

Related Research Articles

<span class="mw-page-title-main">Aromaticity</span> Phenomenon of chemical stability in resonance hybrids of cyclic organic compounds

In chemistry, aromaticity is a property of cyclic (ring-shaped), typically planar (flat) molecular structures with pi bonds in resonance that gives increased stability compared to saturated compounds having single bonds, and other geometric or connective non-cyclic arrangements with the same set of atoms. Aromatic rings are very stable and do not break apart easily. Organic compounds that are not aromatic are classified as aliphatic compounds—they might be cyclic, but only aromatic rings have enhanced stability.

<span class="mw-page-title-main">Sigma bond</span> Covalent chemical bond

In chemistry, sigma bonds are the strongest type of covalent chemical bond. They are formed by head-on overlapping between atomic orbitals. Sigma bonding is most simply defined for diatomic molecules using the language and tools of symmetry groups. In this formal approach, a σ-bond is symmetrical with respect to rotation about the bond axis. By this definition, common forms of sigma bonds are s+s, pz+pz, s+pz and dz2+dz2 . Quantum theory also indicates that molecular orbitals (MO) of identical symmetry actually mix or hybridize. As a practical consequence of this mixing of diatomic molecules, the wavefunctions s+s and pz+pz molecular orbitals become blended. The extent of this mixing depends on the relative energies of the MOs of like symmetry.

In chemistry, bond order, as introduced by Linus Pauling, is defined as the difference between the number of bonds and anti-bonds.

<span class="mw-page-title-main">Delta bond</span> Type of Chemical Bond

In chemistry, delta bonds are covalent chemical bonds, where four lobes of one involved atomic orbital overlap four lobes of the other involved atomic orbital. This overlap leads to the formation of a bonding molecular orbital with two nodal planes which contain the internuclear axis and go through both atoms.

In organic chemistry, a carbyne is a general term for any compound whose structure consists of an electrically neutral carbon atom connected by a single covalent bond and has three non-bonded electrons. The carbon atom has either one or three unpaired electrons, depending on its excitation state; making it a radical. The chemical formula can be written R−C· or R−C, or just CH.

A transition metal carbene complex is an organometallic compound featuring a divalent organic ligand. The divalent organic ligand coordinated to the metal center is called a carbene. Carbene complexes for almost all transition metals have been reported. Many methods for synthesizing them and reactions utilizing them have been reported. The term carbene ligand is a formalism since many are not derived from carbenes and almost none exhibit the reactivity characteristic of carbenes. Described often as M=CR2, they represent a class of organic ligands intermediate between alkyls (−CR3) and carbynes (≡CR). They feature in some catalytic reactions, especially alkene metathesis, and are of value in the preparation of some fine chemicals.

<span class="mw-page-title-main">Chromium(II) acetate</span> Chemical compound

Chromium(II) acetate hydrate, also known as chromous acetate, is the coordination compound with the formula Cr2(CH3CO2)4(H2O)2. This formula is commonly abbreviated Cr2(OAc)4(H2O)2. This red-coloured compound features a quadruple bond. The preparation of chromous acetate once was a standard test of the synthetic skills of students due to its sensitivity to air and the dramatic colour changes that accompany its oxidation. It exists as the dihydrate and the anhydrous forms.

<span class="mw-page-title-main">Persistent carbene</span> Type of carbene demonstrating particular stability

A persistent carbene (also known as stable carbene) is a type of carbene demonstrating particular stability. The best-known examples and by far largest subgroup are the N-heterocyclic carbenes (NHC) (sometimes called Arduengo carbenes), for example diaminocarbenes with the general formula (R2N)2C:, where the four R moieties are typically alkyl and aryl groups. The groups can be linked to give heterocyclic carbenes, such as those derived from imidazole, imidazoline, thiazole or triazole.

A spectrochemical series is a list of ligands ordered by ligand "strength", and a list of metal ions based on oxidation number, group and element. For a metal ion, the ligands modify the difference in energy Δ between the d orbitals, called the ligand-field splitting parameter in ligand field theory, or the crystal-field splitting parameter in crystal field theory. The splitting parameter is reflected in the ion's electronic and magnetic properties such as its spin state, and optical properties such as its color and absorption spectrum.

<span class="mw-page-title-main">Quadruple bond</span> Chemical bond involving eight electrons; has one sigma, two pi, and one delta bond

A quadruple bond is a type of chemical bond between two atoms involving eight electrons. This bond is an extension of the more familiar types double bonds and triple bonds. Stable quadruple bonds are most common among the transition metals in the middle of the d-block, such as rhenium, tungsten, technetium, molybdenum and chromium. Typically the ligands that support quadruple bonds are π-donors, not π-acceptors.

The 18-electron rule is a chemical rule of thumb used primarily for predicting and rationalizing formulas for stable transition metal complexes, especially organometallic compounds. The rule is based on the fact that the valence orbitals in the electron configuration of transition metals consist of five (n−1)d orbitals, one ns orbital, and three np orbitals, where n is the principal quantum number. These orbitals can collectively accommodate 18 electrons as either bonding or nonbonding electron pairs. This means that the combination of these nine atomic orbitals with ligand orbitals creates nine molecular orbitals that are either metal-ligand bonding or non-bonding. When a metal complex has 18 valence electrons, it is said to have achieved the same electron configuration as the noble gas in the period. The rule is not helpful for complexes of metals that are not transition metals, and interesting or useful transition metal complexes will violate the rule because of the consequences deviating from the rule bears on reactivity. The rule was first proposed by American chemist Irving Langmuir in 1921.

<span class="mw-page-title-main">Sextuple bond</span> Covalent bond involving 12 bonding electrons

A sextuple bond is a type of covalent bond involving 12 bonding electrons and in which the bond order is 6. The only known molecules with true sextuple bonds are the diatomic dimolybdenum (Mo2) and ditungsten (W2), which exist in the gaseous phase and have boiling points of 4,639 °C (8,382 °F) and 5,930 °C (10,710 °F) respectively.

Organochromium chemistry is a branch of organometallic chemistry that deals with organic compounds containing a chromium to carbon bond and their reactions. The field is of some relevance to organic synthesis. The relevant oxidation states for organochromium complexes encompass the entire range of possible oxidation states from –4 (d10) in Na4[Cr–IV(CO)4] to +6 (d0) in oxo-alkyl complexes like Cp*CrVI(=O)2Me.

<span class="mw-page-title-main">Organomolybdenum chemistry</span>

Organomolybdenum chemistry is the chemistry of chemical compounds with Mo-C bonds. The heavier group 6 elements molybdenum and tungsten form organometallic compounds similar to those in organochromium chemistry but higher oxidation states tend to be more common.

<span class="mw-page-title-main">Molybdenum(II) acetate</span> Chemical compound

Molybdenum(II) acetate is a coordination compound with the formula Mo2(O2CCH3)4. It is a yellow, diamagnetic, air-stable solid that is slightly soluble in organic solvents. Molybdenum(II) acetate is an iconic example of a compound with a metal-metal quadruple bond.

Potassium octachlorodirhenate(III) is an inorganic compound with the formula K2Re2Cl8. This dark blue salt is well known as an early example of a compound featuring quadruple bond between its metal centers. Although the compound has no practical value, its characterization was significant in opening a new field of research into complexes with quadruple bonds.

<span class="mw-page-title-main">Borylene</span>

A borylene is the boron analogue of a carbene. The general structure is R-B: with R an organic residue and B a boron atom with two unshared electrons. Borylenes are of academic interest in organoboron chemistry. A singlet ground state is predominant with boron having two vacant sp2 orbitals and one doubly occupied one. With just one additional substituent the boron is more electron deficient than the carbon atom in a carbene. For this reason stable borylenes are more uncommon than stable carbenes. Some borylenes such as boron monofluoride (BF) and boron monohydride (BH) the parent compound also known simply as borylene, have been detected in microwave spectroscopy and may exist in stars. Other borylenes exist as reactive intermediates and can only be inferred by chemical trapping.

<span class="mw-page-title-main">Phosphasilene</span>

Phosphasilenes or silylidenephosphanes are a class of compounds with silicon-phosphorus double bonds. Since the electronegativity of phosphorus (2.1) is higher than that of silicon (1.9), the "Si=P" moiety of phosphasilene is polarized. The degree of polarization can be tuned by altering the coordination numbers of the Si and P centers, or by modifying the electronic properties of the substituents. The phosphasilene Si=P double bond is highly reactive, yet with the choice of proper substituents, it can be stabilized via donor-acceptor interaction or by steric congestion.

<span class="mw-page-title-main">Metal–metal bond</span>

In inorganic chemistry, metal–metal bonds describe attractive interactions between metal centers. The simplest examples are found in bimetallic complexes. Metal–metal bonds can be "supported", i.e. be accompanied by one or more bridging ligands, or "unsupported". They can also vary according to bond order. The topic of metal–metal bonding is usually discussed within the framework of coordination chemistry, but the topic is related to extended metallic bonding, which describes interactions between metals in extended solids such as bulk metals and metal subhalides.

Intrinsic bond orbitals (IBO) are localized molecular orbitals giving exact and non-empirical representations of wave functions. They are obtained by unitary transformation and form an orthogonal set of orbitals localized on a minimal number of atoms. IBOs present an intuitive and unbiased interpretation of chemical bonding with naturally arising Lewis structures. For this reason IBOs have been successfully employed for the elucidation of molecular structures and electron flow along the intrinsic reaction coordinate (IRC).


  1. Ritter, Steve (26 September 2005). "Quintuple Bond Makes Its Debut: First stable molecule with fivefold metal–metal bonding is synthesized". Chemical & Engineering News . 83 (39).
  2. Nguyen, Tailuan; Sutton, Andrew D.; Brynda, Marcin; Fettinger, James C.; Long, Gary J.; Power, Philip P. (2005). "Synthesis of a Stable Compound with Fivefold Bonding Between Two Chromium(I) Centers". Science . 310 (5749): 844–847. Bibcode:2005Sci...310..844N. doi:10.1126/science.1116789. PMID   16179432. S2CID   42853922.
  3. Brynda, Marcin; Gagliardi, Laura; Widmark, Per-Olof; Power, Philip P.; Roos, Björn O. (2006). "Quantum Chemical Study of the Quintuple Bond between Two Chromium Centers in [PhCrCrPh]: trans-Bent versus Linear Geometry". Angew. Chem. Int. Ed. 45 (23): 3804–3807. doi:10.1002/anie.200600110. PMID   16671122. Open Access logo PLoS transparent.svg
  4. La Macchia, Giovanni; Gagliardi, Laura; Power, Philip P.; Brynda, Marcin (2008). "Large Differences in Secondary Metal−Arene Interactions in the Transition-Metal Dimers ArMMAr (Ar = Terphenyl; M = Cr, Fe, or Co): Implications for Cr−Cr Quintuple Bonding". J. Am. Chem. Soc. 130 (15): 5104–5114. doi:10.1021/ja0771890. PMID   18335988. S2CID   207046428.
  5. Merino, Gabriel; Donald, Kelling J.; D'Acchioli, Jason S.; Hoffmann, Roald (2007). "The Many Ways To Have a Quintuple Bond". J. Am. Chem. Soc. 129 (49): 15295–15302. doi:10.1021/ja075454b. PMID   18004851. S2CID   18838267.
  6. Gagliardi, Laura; Roos, Björn O. (24 February 2005). "Quantum chemical calculations show that the uranium molecule U2 has a quintuple bond". Nature . 433 (7028): 848–851. Bibcode:2005Natur.433..848G. doi:10.1038/nature03249. PMID   15729337. S2CID   421380.
  7. Dumé, Belle (23 February 2005). "New look for chemical bonds". PhysicsWeb.
  8. Kreisel, Kevin A.; Yap, Glenn P. A.; Dmitrenko, Olga; Landis, Clark R.; Theopold, Klaus H. (2007). "The Shortest Metal–Metal Bond Yet: Molecular and Electronic Structure of a Dinuclear Chromium Diazadiene Complex". J. Am. Chem. Soc. (Communication). 129 (46): 14162–14163. doi:10.1021/ja076356t. PMID   17967028.
  9. Noor, Awal; Wagner, Frank R.; Kempe, Rhett (2008). "Metal–Metal Distances at the Limit: A Coordination Compound with an Ultrashort Chromium–Chromium Bond". Angew. Chem. Int. Ed. 47 (38): 7246–7249. doi:10.1002/anie.200801160. PMID   18698657. S2CID   30480347.
  10. Tsai, Yi-Chou; Hsu, Chia-Wei; Yu, Jen-Shiang K.; Lee, Gene-Hsiang; Wang, Yu; Kuo, Ting-Shen (2008). "Remarkably Short Metal–Metal Bonds: A Lantern-Type Quintuply Bonded Dichromium(I) Complex". Angew. Chem. Int. Ed. 47 (38): 7250–7253. doi:10.1002/anie.200801286. PMID   18683844. S2CID   5510753.
  11. Tsai, Yi-Chou; Chen, Hong-Zhang; Chang, Chie-Chieh; Yu, Jen-Shiang K.; Lee, Gene-Hsiang; Wang, Yu; Kuo, Ting-Shen (2009). "Journey from Mo–Mo Quadruple Bonds to Quintuple Bonds". J. Am. Chem. Soc. 131 (35): 12534–12535. doi:10.1021/ja905035f. PMID   19685872. S2CID   207144833.
  12. Hsu, Chai-Wei; Yu, Jen-Shiang K.; Yen, Chun-Hsu; Lee, Gene-Hsiang; Wang, Yu; Tsa, Yi-Chou (2008). "Quintuply-Bonded Dichromium(I) Complexes Featuring Metal–Metal Bond Lengths of 1.74 Å". Angew. Chem. Int. Ed. 47 (51): 9933–9936. doi:10.1002/anie.200803859. PMID   19016281. S2CID   46033904.
  13. Noor, Awal; Glatz, Germund; Muller, Robert; Kaupp, Martin; Demeshko, Serhiy; Kempe, Rhett (2009). "Carboalumination of a chromium–chromium quintuple bond". Nature Chemistry . 1 (4): 322–325. Bibcode:2009NatCh...1..322N. doi:10.1038/NCHEM.255. PMID   21500603.
  14. Ni, Chengbao; Ellis, Bobby D.; Long, Gary J.; Power, Philip P. (2009). "Reactions of Ar′CrCrAr′ with N2O or N3(1-Ad): complete cleavage of the Cr–Cr quintuple bond interaction". Chemical Communications . 2009 (17): 2332–2334. doi:10.1039/b901494b. PMID   19377676.
  15. Noor, Awal; Schwarz, Stefan; Kempe, Rhett (9 Feb 2015). "Low-Valent Aminopyridinato Chromium Methyl Complexes via Reductive Alkylation and via Oxidative Addition of Iodomethane by a Cr–Cr Quintuple Bond". Organometallics. 34 (11): 2122–2125. doi:10.1021/om501230g.

See also