Salinispora tropica

Salinispora tropica
Scientific classification
Domain:	Bacteria
Kingdom:	Bacillati
Phylum:	Actinomycetota
Class:	Actinomycetes
Order:	Micromonosporales
Family:	Micromonosporaceae
Genus:	Salinispora
Species:	S. tropica
Binomial name
Salinispora tropica Maldonado et al. 2005 [1]
Type strain
ATCC BAA-916 CNB-440 DSM 44818 JCM 13857

Salinispora tropica is an obligate marine actinomycete bacterium species. ^[1] It produces salinosporamide A and salinosporamide B, potential anti-cancer agents, ^{[2] [3]} as well as the polycyclic macrolides sporolide A and B. ^[4]

See also

• Salinispora arenicola
• Salinispora pacifica

References

1. Maldonado, L. A. (2005). "Salinispora arenicola gen. nov., sp. nov. and Salinispora tropica sp. nov., obligate marine actinomycetes belonging to the family Micromonosporaceae". International Journal of Systematic and Evolutionary Microbiology. 55 (5): 1759–1766. doi: 10.1099/ijs.0.63625-0 . ISSN   1466-5026. PMID   16166663.
2. Fenical, W.; Jensen, P.R.; Palladino, M.A.; Lam, K.S.; Lloyd, G.K.; Potts, B.C. (2009). "Discovery and development of the anticancer agent salinosporamide A (NPI-0052)". Bioorganic & Medicinal Chemistry. 17 (6): 2175–2180. doi:10.1016/j.bmc.2008.10.075. PMC   2814440 . PMID   19022674.
3. Williams PG; Buchanan GO; Feling RH; Kauffman CA; Jensen PR; Fenical W (August 2005). "New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica". The Journal of Organic Chemistry . 70 (16): 6196–203. doi:10.1021/jo050511+. PMID   16050677.
4. Buchanan, Greg O.; Williams, Philip G.; Feling, Robert H.; Kauffman, Christopher A.; Jensen, Paul R.; Fenical, William (2005). "Sporolides a and b: Structurally Unprecedented Halogenated Macrolides from the Marine Actinomycete Salinispora tropica". Organic Letters. 7 (13): 2731–2734. doi:10.1021/ol050901i. PMID   15957933.

Further reading

• Udwary DW, Zeigler L, Asolkar RN, et al. (June 2007). "Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica". Proceedings of the National Academy of Sciences of the United States of America . 104 (25): 10376–81. Bibcode:2007PNAS..10410376U. doi: 10.1073/pnas.0700962104 . PMC   1965521 . PMID   17563368.
• Bucarey, S. A.; Penn, K.; Paul, L.; Fenical, W.; Jensen, P. R. (2012). "Genetic Complementation of the Obligate Marine Actinobacterium Salinispora tropica with the Large Mechanosensitive Channel Gene mscL Rescues Cells from Osmotic Downshock". Applied and Environmental Microbiology. 78 (12): 4175–4182. doi:10.1128/AEM.00577-12. ISSN   0099-2240. PMC   3370544 . PMID   22492446.
• Thuan, Nguyen Huy; Yamaguchi, Tokutaro; Lee, Joo Ho; Sohng, Jae Kyung (2013). "Characterization of sterol glucosyltransferase from Salinispora tropica CNB-440: Potential enzyme for the biosynthesis of sitosteryl glucoside". Enzyme and Microbial Technology. 52 (4–5): 234–240. doi:10.1016/j.enzmictec.2013.02.004. ISSN   0141-0229. PMID   23540924.

External links

• LPSN
• "Salinispora tropica". The Encyclopedia of Life .
• WORMS entry
• Type strain of Salinispora tropica at BacDive - the Bacterial Diversity Metadatabase