Setaria cervi

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Setaria cervi
Scientific classification
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S. cervi
Binomial name
Setaria cervi
Rudolphi, 1819

Setaria cervi is a species of parasitic roundworms belonging to the genus Setaria . It infects cattle, bison, yak, reindeer, buffalo, moose, and sheep all over the world. It is most prevalent in Europe and Asia. [1] Different species of Aedes mosquito can transmit the filarial worm. Stable fly Haematobia stimulans is the major vector. The mature roundworms are primarily present in the abdominal (peritoneal) cavity, but are capable of migrating to central nervous system causing serious neurological disease.

Contents

Description

Setaria cervi shows sexual dimorphism as a typical roundworm. Males are relatively smaller measuring 50 mm long and 40 μm wide, while females are much larger measuring 100 mm long and 750 μm wide. Males can be distinguished from those of other species from showing horn-like lateral appendages and characteristic striated bands on the ventral side of the tail. [2] The larvae (microfilariae) are very small and only about 200 μm long. The infective larvae are about 2 mm. [3]

Life cycle

Setaria cervi is transmitted between mammals as definitive hosts and insects as intermediate hosts. Microfilariae are ingested by insect vector when they bite infected host. Once inside the gut of the insect, the larvae shed off their protective covering, a process called exsheathing. This generally take place within 90 minutes of initial ingestion. They penetrate the stomach wall and migrate to the body cavity, haemocoel. After 48 hours they move to fat bodies, where they undergo development by moulting. Second moulting follows after 11 days of infection. Soon after, the juveniles move back to haemocoel to become fully infective larvae. Then they move towards the proboscis from where they are readily released. Infective larvae are characterised by numerous projections called tubercles on the tail end. [4]

The infective larvae are injected into the mammalian host, where they undergo third moulting. By this the size of the body is greatly enlarged. Full maturation into reproductive adults require about a year. The average lifespan of an adult is 1.5 years. [1]

Pathogenicity

Setaria cervi in the body cavity is generally harmless. But the young larvae upon infection can move to the nervous system, where they induce severe neurological disease, as well as in the eye, where they can cause eye damage resulting in blindness. [3]

Treatment

Albendazole is very effective on the microfilariae. [5] Hetrazan, tetramisole and levamisole are most commonly used. [6]

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Microfilaria

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Dirofilaria repens is a filarial nematode that affects dogs and other carnivores such as cats, wolves, coyotes, foxes, and sea lions, as well as muskrats. It is transmitted by mosquitoes. Although humans may become infected as aberrant hosts, the worms fail to reach adulthood while infecting a human body.

Mansonella streptocerca,, is a filarial (arthropod-borne) nematode (roundworm) causing the disease streptocerciasis. It is a common parasite in the skin of humans in the rain forests of Africa, where it is thought to be a parasite of chimpanzees, as well.

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Setaria is a genus of parasitic roundworms that infect domesticated mammals such as pigs, camels, cattle and horses. Some species also infect wild mammals such as deer and antelope. The genus consists of about 43 species. Members of the genus are uniquely parasites in the abdominal cavity of the body. They are mostly large-sized roundworms, possessing an elaborate head (cephalic) region that is characterised by spines, presence of four lips, and well-guarded mouth. Little is known about their pathogenic effects, but some are known to affect nervous system and eye. The larval infective forms are transmitted from one animal to another by the bite of mosquitoes and flies. In addition Setaria marshalli can be transmitted from the womb to new-born calf.

<i>Brugia</i> Genus of roundworms

Brugia is a genus for a group of small roundworms. They are among roundworms that cause the parasitic disease filariasis. Specifically, of the three species known, Brugia malayi and Brugia timori cause lymphatic filariasis in humans; and Brugia pahangi and Brugia patei infect domestic cats, dogs and other animals. They are transmitted by the bite of mosquitos.

References

  1. 1 2 Anderson, R.C. (2000). Nematode Parasites of Vertebrates Their Development and Transmission (2nd ed.). Wallingford: CAB International. pp. 479–480. ISBN   978-0-8519-9786-5.
  2. Almeida, Andrew J.; Deobhankar, Kedar P.; Bhopale, Mahendra K.; Zaman, Viquar; Renapurkar, Dinkar M. (1991). "Scanning electron microscopy of Setaria cervi adult male worms". International Journal for Parasitology. 21 (1): 119–121. doi:10.1016/0020-7519(91)90130-Y. PMID   2040560.
  3. 1 2 Cheng, Thomas C. (1986). General Parasitology (2nd ed.). Oxford: Elsevier Science. p. 546. ISBN   978-0-3231-4010-2.
  4. Ashford, R.W. (2001). Encyclopedia of Arthropod-transmitted Infections of Man and Domesticated Animals. Wallingford, Oxon, UK: CABI Publishing. pp. 465–467. ISBN   9781845933166.
  5. Nayak, A.; Gayen, P.; Saini, P.; Maitra, S.; Sinha Babu, S.P. (2011). "Albendazole induces apoptosis in adults and microfilariae of Setaria cervi". Experimental Parasitology. 128 (3): 236–242. doi:10.1016/j.exppara.2011.03.005.
  6. Khatoon, H; Baqui, A; Wajihullah; Ansari, JA (1983). "Effect of anthelmintics on the enzyme activities of Setaria cervi (Nematoda: Filarioidea)". Angewandte Parasitologie. 24 (2): 72–5. PMID   6614575.