Signal peptidase II

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Signal peptidase II
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EC no. 3.4.23.36
CAS no. 171715-14-3
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Signal peptidase II (EC 3.4.23.36, premurein-leader peptidase, prolipoprotein signal peptidase, leader peptidase II, premurein leader proteinase) is an enzyme. [1] [2] [3]

This enzyme catalyses a chemical reaction. It releases signal peptides from murein prolipoprotein and other bacterial membrane prolipoproteins. It also hydrolyses -Xaa-Yaa-Zaa-(S,diacylglyceryl)Cys-, in which Yaa (Ala or Ser) and Zaa (Gly or Ala) have small neutral sidechains, and Xaa is hydrophobic (preferably Leu).

This enzyme is present in bacterial inner membranes.

Related Research Articles

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<span class="mw-page-title-main">DD-transpeptidase</span>

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<span class="mw-page-title-main">Thermolysin</span>

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<span class="mw-page-title-main">HM13</span> Protein-coding gene in the species Homo sapiens

Minor histocompatibility antigen H13 is a protein that in humans is encoded by the HM13 gene.

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Xaa-Pro dipeptidyl-peptidase (EC 3.4.14.11, X-prolyl dipeptidyl aminopeptidase, PepX, X-prolyl dipeptidyl peptidase is an enzyme. It catalyses the following chemical reaction

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Pyroglutamyl-peptidase II is an enzyme. This enzyme catalyses the following chemical reaction

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C-terminal processing peptidase is an enzyme. This enzyme catalyses the following chemical reaction

Adenain is an enzyme. This enzyme catalyses the following chemical reaction

References

  1. Dev IK, Ray PH (June 1990). "Signal peptidases and signal peptide hydrolases". Journal of Bioenergetics and Biomembranes. 22 (3): 271–90. doi:10.1007/bf00763168. PMID   2202720.
  2. Zhao XJ, Wu HC (March 1992). "Nucleotide sequence of the Staphylococcus aureus signal peptidase II (lsp) gene". FEBS Letters. 299 (1): 80–4. doi:10.1016/0014-5793(92)80105-p. PMID   1544479.
  3. Sankaran K, Wu HC (1995). Bacterial prolipoprotein signal peptidase. Methods in Enzymology. Vol. 248. pp. 169–80. doi:10.1016/0076-6879(95)48014-5. PMID   7674920.