The Southwest Football Conference is a five-member IHSAA-sanctioned conference currently spanning Daviess, Greene, Knox, and Putnam counties in Southwest and West Central Indiana. It was founded in 2004 as the Southwest Seven Conference, by teams in southwestern Indiana whose regular conferences do not play the sport. The conference lost a member in 2013, as Linton-Stockton pursued an independent schedule to better prepare themselves for the playoffs. The conference lost another in 2014, as Union (Dugger) was closed, then lost Wood Memorial in 2018 after the school's football program was shuttered. Cloverdale joined the conference in 2026, leaving the Western Indiana Conference.