The Southern Athletic Conference is an IHSAA-sanctioned athletic located within Clark, Harrison, and Jackson Counties in South Central Indiana. The conference began in 1974 as a four school conference, and grew to eight members within five years as other local conferences disbanded. The conference has lost two schools in the years since; both left for the Mid-Southern Conference. The Southern also had schools that had dual membership in other conferences at the same time, though by 1986, all of these schools entered full membership with a sole conference.
| School | Location | Mascot | Colors | Enrollment | IHSAA Class | County | Year joined | Previous conference |
|---|---|---|---|---|---|---|---|---|
| Borden* | Borden | Braves | 228 | A | 10 Clark | 1974 | Lost River | |
| Crothersville* | Crothersville | Tigers | 180 | A | 36 Jackson | 1974 | Mid-Hoosier | |
| Henryville | Henryville | Hornets | 347 | AA | 10 Clark | 1977 | Lost River | |
| Lanesville | Lanesville | Eagles | 237 | A | 31 Harrison | 1979 | Blue River | |
| New Washington | New Washington | Mustangs | 273 | A | 10 Clark | 1974 | Dixie-Monon | |
| South Central (Elizabeth) | Elizabeth | Rebels | 277 | A | 31 Harrison | 1979 | Blue River |
| School | Location | Mascot | Colors | County | Year joining | Previous conference |
|---|---|---|---|---|---|---|
| Clarksville | Clarksville | Generals | 10 Clark | 2025 | Independent | |
| Eastern (Pekin) | New Pekin | Musketeers | 88 Washington | 2025 | Mid-Southern |
| School | Location | Mascot | Colors | County | Year joined | Previous conference | Year left | Conference joined |
|---|---|---|---|---|---|---|---|---|
| Austin* | Austin | Eagles | 72 Scott | 1974 | Mid-Southern | 1986 | Mid-Southern | |
| Eastern (Pekin)* | New Pekin | Musketeers | 88 Washington | 1975 | Lost River | 2003 | Mid-Southern |