Streptomyces microflavus

Last updated

Streptomyces microflavus
Scientific classification
Domain:
Phylum:
Class:
Order:
Family:
Genus:
Species:
S. microflavus
Binomial name
Streptomyces microflavus
Waksman and Henrici 1948 [1]
Type strain
AS 4.1428, ATCC 13231, ATCC 25474, ATCC B-2888, BCRC 12084, CBS .884.69, CBS 124.18, CBS 884.69, CBS Krainsky, CCRC 12084, CGMCC 4.1428, DSM 40331, ETH 10206, ETH 31561, ETH 31582, HAMBI 1019, IFO 13062, IMRU 3332, IMSNU 21062, INA 3332, ISP 5331, JCM 4496, KCC S-0496, KCTC 19055, Lanoot R-8689, LMG 19327, NBRC 13062, NRRL B-2156, NRRL B-2888, NRRL B-B-2888, NRRL-ISP 5331, PSA 122, R-8689, RIA 1254, VKM Ac-971, VTT E-011975 [2]
Synonyms [3] [4]
  • "Actinomyces alboviridis" Duché 1934
  • "Actinomyces cretaceus" (Kruger 1905) Krasil'nikov 1941
  • "Actinomyces fulvissimus" Jensen 1930
  • "Actinomyces griseus subsp. alpha" Ciferri 1927
  • "Actinomyces lipmanii" Waksman and Curtis 1916
  • "Actinomyces microflavus" Krainsky 1914
  • "Actinomyces willmorei" Erikson 1935
  • Streptomyces alboviridis(Duché 1934) Pridham et al. 1958 (Approved Lists 1980)
  • Streptomyces fulvissimus(Jensen 1930) Waksman and Henrici 1948 (Approved Lists 1980)
  • Streptomyces griseus subsp. alpha(Ciferri 1927) Pridham 1970 (Approved Lists 1980)
  • Streptomyces griseus subsp. cretosusPridham 1970 (Approved Lists 1980)
  • Streptomyces lipmanii(Waksman and Curtis 1916) Waksman and Henrici 1948 (Approved Lists 1980)
  • Streptomyces luridiscabieiPark et al. 2003
  • Streptomyces willmorei(Erikson 1935) Waksman and Henrici 1948 (Approved Lists 1980)

Streptomyces microflavus is a bacterium species from the genus of Streptomyces which has been isolated from soil. [1] [3] Streptomyces microflavus produces nemadectin, fattiviracin A1, milbemycin and deoxyuridines. [5] [6] [7] Streptomyces microflavus also produces the ionophore valinomycin. [8] [9] [10] [11] Streptomyces microflavus is also known to cause potato common scab disease in Korea. [12]

Contents

See also

Related Research Articles

<i>Streptomyces</i> Genus of bacteria

Streptomyces is the largest genus of Actinobacteria and the type genus of the family Streptomycetaceae. Over 500 species of Streptomyces bacteria have been described. As with the other Actinobacteria, streptomycetes are gram-positive, and have genomes with high GC content. Found predominantly in soil and decaying vegetation, most streptomycetes produce spores, and are noted for their distinct "earthy" odor that results from production of a volatile metabolite, geosmin.

Amycolatopsis is a genus of high GC-content bacteria within the family Pseudonocardiaceae. The genus is known for producing many types of antibiotics, including

5-HT<sub>6</sub> receptor Protein-coding gene in the species Homo sapiens

The 5HT6 receptor is a subtype of 5HT receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5HT). It is a G protein-coupled receptor (GPCR) that is coupled to Gs and mediates excitatory neurotransmission. HTR6 denotes the human gene encoding for the receptor.

Metabotropic glutamate receptor 2

Metabotropic glutamate receptor 2 (mGluR2) is a protein that, in humans, is encoded by the GRM2 gene. mGluR2 is a G protein-coupled receptor (GPCR) that couples with the Gi alpha subunit. The receptor functions as an autoreceptor for glutamate, that upon activation, inhibits the emptying of vesicular contents at the presynaptic terminal of glutamatergic neurons.

Enediyne

Enediynes are organic compounds containing two triple bonds and one double bond.

9-Aminomethyl-9,10-dihydroanthracene

AMDA (9-Aminomethyl-9,10-dihydroanthracene) is an organic compound which acts as a potent and selective antagonist for the 5-HT2A receptor. It has been used to help study the shape of the 5-HT2A protein, and develop a large family of related derivatives with even higher potency and selectivity.

The Center for Pharmaceutical Research and Innovation (CPRI) is a University of Kentucky-based research center established by the University of Kentucky College of Pharmacy in 2012 to facilitate academic translational research and drug discovery/drug development. The UK CPRI specializes in natural product-based drug discovery from microbes found within unique environments including underground and surface coal mines, acid mine drainage and mine reclamation sites, thermal vents associated with underground coal mine fires and deep-well drilling for carbon sequestration. CPRI also provides core support for medicinal chemistry, assay development and screening, rational drug design, computational chemistry, and ADMET. The Center collaborates with investigators focused on drug discovery or development research in the areas of cancer, drug and alcohol addiction, cardiovascular disease, infectious disease, regenerative medicine and neurodegenerative disease.

Cyclothiazomycin Chemical compound

The cyclothiazomycins are a group of natural products, classified as thiopeptides, which are produced by various Streptomyces species of bacteria.

Streptomyces capoamus is a bacterium species from the genus of Streptomyces which has been isolated from soil from Iceland. Streptomyces capoamus produces capomycin, ciclamycin O, ciclamycin 4, anthracycline, ciclacidin A, ciclacidin B and ciclamicin.

Streptomyces flavoviridis is a bacterium species from the genus of Streptomyces which has been isolated from soil. Streptomyces flavoviridis produces phleomycin and zorbamycin.

Streptomyces heilongjiangensis is a bacterium species from the genus of Streptomyces which has been isolated from the root surface of the soybean Glycine max in Hulin in the Heilongjiang province in China. Streptomyces heilongjiangensis produces borrelidin.

Streptomyces sanglieri is a bacterium species from the genus of Streptomyces which has been isolated from soil from a hay meadow. Streptomyces sanglieri produces the antibiotic lactonamycin Z.

Embleya scabrispora is a bacterium species from the genus Embleya which has been isolated from soil from Japan. Embleya scabrispora produces the antibiotic hitachimycin.

Streptomyces xinghaiensis is a bacterium species from the genus of Streptomyces which has been isolated from marine sediments from Xinghai Bay near Dalian in China.

Streptomyces daqingensis is a bacterium species from the genus of Streptomyces which has been isolated from saline-alkaline soil in Heilongjiang in China.

Jadomycin Chemical compound

A jadomycin is a natural product produced by Streptomyces venezuelae ISP5230 (ATCC10712), the organism which is most well known for making the antibiotic chloramphenicol. The name jadomycin is applied to a family of related angucyclines which are distinguished by the E ring, which is derived from an amino acid. The amino acid incorporation which forms the E-ring is a chemical reaction, rather than enzymatic, an uncommon occurrence in biosynthesis. As such a number of jadomycins incorporating different amino acids have been discovered. Jadomycin A was the first compound of this family to be isolated and constitutes the angucylic backbone with L-isoleucine incorporated into the E-ring. A related analog, jadomycin B, is modified by glycosylation with a 2,6-dideoxy sugar, L-digitoxose. Jadomycins have cytotoxic and antibacterial properties.

Streptomyces lasiicapitis is a bacterium species from the genus of Streptomyces which has been isolated from the head of the ant Lasius fuliginosus. Streptomyces lasiicapitis produces the antibiotic kanchanamycin.

C-1027 Chemical compound

C-1027 or Lidamycin is an antitumor antibiotic consisting of a complex of an enediyne chromophore and an apoprotein. It shows antibiotic activity against most Gram-positive bacteria. It is one of the most potent cytotoxic molecules known, due to its induction of a higher ratio of DNA double-strand breaks than single-strand breaks.

Streptomyces durbertensis is a bacterium species from the genus of Streptomyces which has been isolated from saline-alkali soil from the Heilongjiang Province in China.

Lydicamycin is an organic compound with the molecular formula C47H74N4O10. Lydicamycin is an antibiotic with activity against Gram-positive bacteria. The bacteria Streptomyces lydicamycinicus and Streptomyces platensis produces lydicamycin.

References

  1. 1 2 LPSN bacterio.net
  2. Straininfo of Streptomyces microflavus
  3. 1 2 Deutsche Sammlung von Mikroorganismen und Zellkulturen
  4. UniProt
  5. Xiang, WS; Wang, JD; Wang, M; Wang, XJ (April 2010). "New nemadectin congener from Streptomyces microflavus neau3: fermentation, isolation, structure elucidation and biological activities". The Journal of Antibiotics. 63 (4): 171–5. doi:10.1038/ja.2010.12. PMID   20186170.
  6. Uyeda, M; Yokomizo, K; Miyamoto, Y; Habib, EE (September 1998). "Fattiviracin A1, a novel antiherpetic agent produced by Streptomyces microflavus Strain No. 2445. I. Taxonomy, fermentation, isolation, physico-chemical properties and structure elucidation". The Journal of Antibiotics. 51 (9): 823–8. doi: 10.7164/antibiotics.51.823 . PMID   9820232.
  7. Li, Ke; Li, Qiao-Lian; Ji, Nai-Yun; Liu, Bo; Zhang, Wei; Cao, Xu-Peng (26 April 2011). "Deoxyuridines from the Marine Sponge Associated Actinomycete Streptomyces microflavus". Marine Drugs. 9 (12): 690–695. doi:10.3390/md9050690. PMC   3111175 . PMID   21673882.
  8. www.abcam.com
  9. S., Huneck; Joachim, Thiem (2014). RÖMPP Lexikon Naturstoffe. Georg Thieme Verlag. ISBN   978-3-13-179541-0.
  10. Ternes, von Waldemar (2013). Biochemie der Elemente anorganische Chemie biologischer Prozesse. Berlin: Springer. ISBN   978-3-8274-3020-5.
  11. Jerry L. Atwood, ed. (2004). Encyclopedia of supramolecular chemistry. New York, NY [u.a.]: Dekker. ISBN   0-8247-4723-2.
  12. Park, D. H. (2003). "Streptomyces luridiscabiei sp. nov., Streptomyces puniciscabiei sp. nov. and Streptomyces niveiscabiei sp. nov., which cause potato common scab disease in Korea". International Journal of Systematic and Evolutionary Microbiology. 53 (6): 2049–2054. doi:10.1099/ijs.0.02629-0. ISSN   1466-5026. PMID   14657144.

Further reading