TMX1

TMX1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1X5E
Identifiers
Aliases	TMX1 , PDIA11, TMX, TXNDC, TXNDC1, thioredoxin related transmembrane protein 1
External IDs	OMIM: 610527 MGI: 1919986 HomoloGene: 12482 GeneCards: TMX1
Gene location (Human)
Chr.	Chromosome 14 (human)
End	51,257,655 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	70,514,814 bp
RNA expression pattern
	Top expressed in
	tibia; ; germinal epithelium; ; cancellous bone; ; cavity of mouth; ; jejunal mucosa; ; superficial temporal artery; ; secondary oocyte; ; retinal pigment epithelium; ; monocyte; ; periodontal fiber;
	Top expressed in
	retinal pigment epithelium; ; cumulus cell; ; ciliary body; ; Paneth cell; ; fossa; ; condyle; ; aortic valve; ; supraoptic nucleus; ; ascending aorta; ; iris;
	More reference expression data
	n/a
Gene ontology
Molecular function	disulfide oxidoreductase activity ; protein disulfide isomerase activity ;
Cellular component	integral component of membrane ; membrane ; endoplasmic reticulum membrane ; endoplasmic reticulum ;
Biological process	protein folding ; response to endoplasmic reticulum stress ; cell redox homeostasis ;
	Sources:Amigo / QuickGO
Orthologs
	81542
	72736
	ENSG00000139921
	ENSMUSG00000021072
	Q9H3N1
	Q8VBT0
	NM_030755
	NM_028339
	NP_110382
	NP_082615
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 17, 2022

Thioredoxin-related transmembrane protein 1 is a protein that in humans is encoded by the TMX1 gene.^[5]^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000139921 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021072 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Matsuo Y, Akiyama N, Nakamura H, Yodoi J, Noda M, Kizaka-Kondoh S (Mar 2001). "Identification of a novel thioredoxin-related transmembrane protein" (PDF). J Biol Chem. 276 (13): 10032–8. doi: 10.1074/jbc.M011037200 . PMID 11152479.
↑ "Entrez Gene: TXNDC1 thioredoxin domain containing 1".

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Heilig R, Eckenberg R, Petit JL, et al. (2003). "The DNA sequence and analysis of human chromosome 14". Nature. 421 (6923): 601–7. Bibcode:2003Natur.421..601H. doi: 10.1038/nature01348 . PMID 12508121.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697 . PMID 12975309.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC 514446 . PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi: 10.1093/dnares/12.2.117 . PMID 16303743.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129 . PMID 16344560.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID 17081983.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000139921 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021072 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11152479-5] Matsuo Y, Akiyama N, Nakamura H, Yodoi J, Noda M, Kizaka-Kondoh S (Mar 2001). "Identification of a novel thioredoxin-related transmembrane protein" (PDF). J Biol Chem. 276 (13): 10032–8. doi: 10.1074/jbc.M011037200 . PMID 11152479.

[entrez-6] "Entrez Gene: TXNDC1 thioredoxin domain containing 1".

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TMX1

Related Research Articles

References

Further reading