TXNDC5

Last updated
TXNDC5
Protein TXNDC5 PDB 2diz.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases TXNDC5 , ENDOPDI, ERP46, HCC-2, PDIA15, STRF8, UNQ364, HCC2, thioredoxin domain containing 5
External IDs OMIM: 616412; MGI: 2145316; HomoloGene: 11125; GeneCards: TXNDC5; OMA:TXNDC5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_030810
NM_001145549
NM_022085

NM_001289598
NM_001289599
NM_145367

RefSeq (protein)

NP_001139021
NP_110437

NP_001276527
NP_001276528
NP_663342

Location (UCSC) Chr 6: 7.88 – 7.91 Mb Chr 13: 38.68 – 38.71 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Thioredoxin domain-containing protein 5 is a protein that in humans is encoded by the TXNDC5 gene. [5]

Contents

Function

This gene encodes a protein disulfide-isomerase. [6] Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. This gene can be co-transcribed with the upstream gene MUTED. [5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000239264 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000038991 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "Entrez Gene: TXNDC5 thioredoxin domain containing 5".
  6. Galligan JJ, Petersen DR (July 2012). "The human protein disulfide isomerase gene family". Human Genomics. 6 (6): 6. doi: 10.1186/1479-7364-6-6 . PMC   3500226 . PMID   23245351.

Further reading